Annotation Categories of the Plasmid Cluster
Summary of the plasmid cluster
Basic Information about the Plasmid Cluster
Cluster Information |
Plasmid Cluster ID |
C192 |
Reference Plasmid |
CP103219.1 |
Reference Plasmid Size |
35266 |
Reference Plasmid GC Content |
0.36 |
Reference Plasmid Mobility Type |
non-mobilizable |
Mutation sites in the plasmid cluster
The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..
mutid |
gname |
pos |
count |
tissue |
frequnt |
biotype |
consequence |
impact |
nucchange |
aachange |
M0147312 |
ENGMLIPH_00002 |
719 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
43T>C |
Leu15Leu |
M0147313 |
ENGMLIPH_00003 |
1314 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
33T>C |
Pro11Pro |
M0147314 |
ENGMLIPH_00004 |
1369 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
678T>C |
Ile226Ile |
M0147315 |
ENGMLIPH_00004 |
1555 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
492C>T |
Asn164Asn |
M0147316 |
ENGMLIPH_00004 |
1558 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
489T>C |
Pro163Pro |
M0147317 |
ENGMLIPH_00004 |
1702 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
345A>G |
Leu115Leu |
M0147318 |
ENGMLIPH_00004 |
1909 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
138C>T |
Val46Val |
M0147319 |
ENGMLIPH_00002 |
2049 |
10 |
Gut |
0.53 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1288G>A |
None |
M0147320 |
ENGMLIPH_00002 |
2163 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1402A>G |
None |
M0147321 |
ENGMLIPH_00002 |
2195 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1434A>G |
None |
M0147322 |
ENGMLIPH_00002 |
2199 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1438C>T |
None |
M0147323 |
ENGMLIPH_00002 |
2228 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1467T>C |
None |
M0147324 |
ENGMLIPH_00002 |
2268 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1507T>C |
None |
M0147325 |
ENGMLIPH_00002 |
2283 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1522A>G |
None |
M0147326 |
ENGMLIPH_00002 |
2288 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1527T>A |
None |
M0147327 |
ENGMLIPH_00002 |
2289 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1528T>A |
None |
M0147328 |
ENGMLIPH_00002 |
2301 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1540A>G |
None |
M0147329 |
ENGMLIPH_00002 |
2351 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1590C>T |
None |
M0147330 |
ENGMLIPH_00002 |
2472 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1711A>G |
None |
M0147331 |
ENGMLIPH_00002 |
2495 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1734T>G |
None |
M0147332 |
ENGMLIPH_00005 |
2594 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
46A>G |
Lys16Glu |
M0147333 |
ENGMLIPH_00005 |
2758 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
210T>C |
His70His |
M0147334 |
ENGMLIPH_00005 |
2785 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
237T>C |
Asn79Asn |
M0147335 |
ENGMLIPH_00005 |
2792 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
244C>A |
Leu82Ile |
M0147336 |
ENGMLIPH_00005 |
2812 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
264G>A |
Glu88Glu |
M0147337 |
ENGMLIPH_00006 |
2872 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
19A>G |
Asn7Asp |
M0147338 |
ENGMLIPH_00006 |
3100 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
247G>A |
Val83Ile |
M0147339 |
ENGMLIPH_00006 |
3117 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
264G>A |
Leu88Leu |
M0147340 |
ENGMLIPH_00006 |
3171 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
318G>A |
Lys106Lys |
M0147341 |
ENGMLIPH_00006 |
3320 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
467T>C |
Phe156Ser |
M0147342 |
ENGMLIPH_00006 |
3585 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
732A>G |
Leu244Leu |
M0147343 |
ENGMLIPH_00006 |
3620 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
767G>A |
Gly256Asp |
M0147344 |
ENGMLIPH_00006 |
3723 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
870G>A |
Arg290Arg |
M0147345 |
ENGMLIPH_00006 |
3795 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
942A>G |
Gln314Gln |
M0147346 |
ENGMLIPH_00006 |
3822 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
969T>C |
Tyr323Tyr |
M0147347 |
ENGMLIPH_00006 |
3864 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1011C>T |
Ser337Ser |
M0147348 |
ENGMLIPH_00006 |
3907 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1054C>T |
Leu352Leu |
M0147349 |
ENGMLIPH_00006 |
3915 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1062A>G |
Glu354Glu |
M0147350 |
ENGMLIPH_00006 |
4013 |
7 |
Gut |
0.37 |
protein_coding |
missense_variant |
MODERATE |
1160C>A |
Thr387Asn |
M0147351 |
ENGMLIPH_00006 |
4035 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1182C>T |
Phe394Phe |
M0147352 |
ENGMLIPH_00006 |
4085 |
4 |
Gut |
0.21 |
protein_coding |
missense_variant |
MODERATE |
1232C>T |
Thr411Met |
M0147353 |
ENGMLIPH_00006 |
4104 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1251C>T |
Ile417Ile |
M0147354 |
ENGMLIPH_00006 |
4230 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1377C>T |
Asp459Asp |
M0147355 |
ENGMLIPH_00002 |
4291 |
8 |
Gut |
0.42 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3530T>C |
None |
M0147356 |
ENGMLIPH_00009 |
4921 |
3 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
129G>A |
Glu43Glu |
M0147357 |
ENGMLIPH_00009 |
5044 |
3 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
252G>A |
Glu84Glu |
M0147358 |
ENGMLIPH_00009 |
5161 |
3 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
369C>T |
Ile123Ile |
M0147359 |
ENGMLIPH_00009 |
5512 |
3 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
720G>A |
Lys240Lys |
M0147360 |
ENGMLIPH_00009 |
5627 |
3 |
Gut |
0.16 |
protein_coding |
missense_variant |
MODERATE |
835C>G |
Leu279Val |
M0147361 |
ENGMLIPH_00009 |
5695 |
3 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
903A>G |
Ala301Ala |
M0147362 |
ENGMLIPH_00016 |
10878 |
6 |
Gut |
0.32 |
protein_coding |
missense_variant |
MODERATE |
1164A>G |
Ile388Met |
M0147363 |
ENGMLIPH_00016 |
10892 |
6 |
Gut |
0.32 |
protein_coding |
missense_variant |
MODERATE |
1150T>C |
Ser384Pro |
M0147364 |
ENGMLIPH_00016 |
11472 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
570C>T |
Pro190Pro |
M0147365 |
ENGMLIPH_00016 |
11586 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
456T>C |
Ser152Ser |
M0147366 |
ENGMLIPH_00016 |
11607 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
435A>G |
Thr145Thr |
M0147367 |
ENGMLIPH_00016 |
11868 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
174T>G |
Val58Val |
M0147368 |
ENGMLIPH_00016 |
11916 |
4 |
Gut |
0.21 |
protein_coding |
synonymous_variant |
LOW |
126C>T |
Thr42Thr |
M0147369 |
ENGMLIPH_00017 |
12122 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
1142A>G |
Glu381Gly |
M0147370 |
ENGMLIPH_00017 |
12139 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1125A>G |
Leu375Leu |
M0147371 |
ENGMLIPH_00017 |
12193 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
1071G>A |
Leu357Leu |
M0147372 |
ENGMLIPH_00017 |
12427 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
837G>A |
Glu279Glu |
M0147373 |
ENGMLIPH_00017 |
12637 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
627A>G |
Leu209Leu |
M0147374 |
ENGMLIPH_00017 |
12832 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
432A>G |
Pro144Pro |
M0147375 |
ENGMLIPH_00017 |
12949 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
315T>C |
Thr105Thr |
M0147376 |
ENGMLIPH_00017 |
13009 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
255A>G |
Glu85Glu |
M0147377 |
ENGMLIPH_00017 |
13108 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
156G>A |
Gly52Gly |
M0147378 |
ENGMLIPH_00018 |
13373 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
630A>T |
Gly210Gly |
M0147379 |
ENGMLIPH_00018 |
13484 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
519A>G |
Lys173Lys |
M0147380 |
ENGMLIPH_00018 |
13523 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
480A>G |
Pro160Pro |
M0147381 |
ENGMLIPH_00018 |
13535 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
468A>C |
Ile156Ile |
M0147382 |
ENGMLIPH_00018 |
13637 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
366T>C |
Thr122Thr |
M0147383 |
ENGMLIPH_00018 |
13658 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
345T>A |
Pro115Pro |
M0147384 |
ENGMLIPH_00018 |
13911 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
92A>G |
Asn31Ser |
M0147385 |
ENGMLIPH_00015 |
14006 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3918G>T |
None |
M0147386 |
ENGMLIPH_00015 |
14032 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3944G>A |
None |
M0147387 |
ENGMLIPH_00015 |
14093 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4005C>T |
None |
M0147388 |
ENGMLIPH_00019 |
14148 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
591A>C |
Arg197Ser |
M0147389 |
ENGMLIPH_00019 |
14184 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
555G>A |
Lys185Lys |
M0147390 |
ENGMLIPH_00019 |
14207 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
532G>A |
Val178Ile |
M0147391 |
ENGMLIPH_00019 |
14292 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
447G>A |
Arg149Arg |
M0147392 |
ENGMLIPH_00019 |
14403 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
336A>G |
Ala112Ala |
M0147393 |
ENGMLIPH_00019 |
14442 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
297A>T |
Pro99Pro |
M0147394 |
ENGMLIPH_00019 |
14529 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
210C>T |
Thr70Thr |
M0147395 |
ENGMLIPH_00019 |
14559 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
180A>G |
Val60Val |
M0147396 |
ENGMLIPH_00015 |
14800 |
10 |
Gut |
0.53 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4712T>A |
None |
M0147397 |
ENGMLIPH_00020 |
14894 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
60T>C |
Tyr20Tyr |
M0147398 |
ENGMLIPH_00020 |
14957 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
123T>A |
Gly41Gly |
M0147399 |
ENGMLIPH_00020 |
15059 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
225T>C |
Ser75Ser |
M0147400 |
ENGMLIPH_00020 |
15065 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
231A>G |
Glu77Glu |
M0147401 |
ENGMLIPH_00020 |
15075 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
241G>A |
Ala81Thr |
M0147402 |
ENGMLIPH_00020 |
15113 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
279A>G |
Ala93Ala |
M0147403 |
ENGMLIPH_00020 |
15128 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
294T>C |
Ile98Ile |
M0147404 |
ENGMLIPH_00020 |
15248 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
414A>G |
Leu138Leu |
M0147405 |
ENGMLIPH_00021 |
15439 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
39C>T |
Asp13Asp |
M0147406 |
ENGMLIPH_00021 |
15457 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
57T>C |
Gly19Gly |
M0147407 |
ENGMLIPH_00021 |
15526 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
126T>C |
His42His |
M0147408 |
ENGMLIPH_00021 |
15531 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
131A>G |
Lys44Arg |
M0147409 |
ENGMLIPH_00021 |
15544 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
144T>C |
Ala48Ala |
M0147410 |
ENGMLIPH_00022 |
15710 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
125G>A |
Gly42Glu |
M0147411 |
ENGMLIPH_00022 |
15726 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
141G>T |
Thr47Thr |
M0147412 |
ENGMLIPH_00022 |
15757 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
172A>G |
Lys58Glu |
M0147413 |
ENGMLIPH_00022 |
15903 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
318A>G |
Pro106Pro |
M0147414 |
ENGMLIPH_00022 |
15905 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
320T>C |
Phe107Ser |
M0147415 |
ENGMLIPH_00022 |
15911 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
326A>T |
His109Leu |
M0147416 |
ENGMLIPH_00023 |
16153 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
120C>T |
Ser40Ser |
M0147417 |
ENGMLIPH_00023 |
16154 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
121G>T |
Ala41Ser |
M0147418 |
ENGMLIPH_00023 |
16177 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
144C>T |
Ser48Ser |
M0147419 |
ENGMLIPH_00023 |
16208 |
11 |
Gut |
0.58 |
protein_coding |
missense_variant |
MODERATE |
175A>G |
Asn59Asp |
M0147420 |
ENGMLIPH_00023 |
16303 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
270C>T |
His90His |
M0147421 |
ENGMLIPH_00023 |
16312 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
279G>A |
Glu93Glu |
M0147422 |
ENGMLIPH_00023 |
16315 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
282T>C |
Tyr94Tyr |
M0147423 |
ENGMLIPH_00023 |
16318 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
285G>T |
Leu95Leu |
M0147424 |
ENGMLIPH_00023 |
16324 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
291C>A |
Gly97Gly |
M0147425 |
ENGMLIPH_00024 |
16495 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
120G>A |
Val40Val |
M0147426 |
ENGMLIPH_00024 |
16603 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
228T>C |
Thr76Thr |
M0147427 |
ENGMLIPH_00016 |
16704 |
10 |
Gut |
0.53 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4663T>C |
None |
M0147428 |
ENGMLIPH_00025 |
17156 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
375A>G |
Lys125Lys |
M0147429 |
ENGMLIPH_00025 |
17184 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
403T>A |
Cys135Ser |
M0147430 |
ENGMLIPH_00025 |
17231 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
450A>G |
Lys150Lys |
M0147431 |
ENGMLIPH_00025 |
17525 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
744A>G |
Gly248Gly |
M0147432 |
ENGMLIPH_00025 |
17636 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
855A>G |
Pro285Pro |
M0147433 |
ENGMLIPH_00025 |
17681 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
900A>T |
Leu300Leu |
M0147434 |
ENGMLIPH_00025 |
18002 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1221T>C |
Asn407Asn |
M0147435 |
ENGMLIPH_00025 |
18050 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1269A>G |
Gly423Gly |
M0147436 |
ENGMLIPH_00025 |
18309 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1528C>T |
Leu510Leu |
M0147437 |
ENGMLIPH_00025 |
18389 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
1608T>C |
Asn536Asn |
M0147438 |
ENGMLIPH_00025 |
18466 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
1685A>C |
Tyr562Ser |
M0147439 |
ENGMLIPH_00025 |
18500 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1719C>T |
Pro573Pro |
M0147440 |
ENGMLIPH_00025 |
18636 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
1855T>A |
Tyr619Asn |
M0147441 |
ENGMLIPH_00025 |
18637 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
1856A>G |
Tyr619Cys |
M0147442 |
ENGMLIPH_00025 |
18986 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
2205G>A |
Thr735Thr |
M0147443 |
ENGMLIPH_00026 |
19542 |
10 |
Gut |
0.53 |
protein_coding |
synonymous_variant |
LOW |
171C>A |
Val57Val |
M0147444 |
ENGMLIPH_00027 |
19916 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
311G>A |
Ser104Asn |
M0147445 |
ENGMLIPH_00028 |
20369 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
156G>A |
Gln52Gln |
M0147446 |
ENGMLIPH_00028 |
20379 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
166T>G |
Ser56Ala |
M0147447 |
ENGMLIPH_00029 |
21545 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
273C>T |
Ser91Ser |
M0147448 |
ENGMLIPH_00029 |
21555 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
283A>G |
Asn95Asp |
M0147449 |
ENGMLIPH_00029 |
21591 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
319C>A |
Arg107Arg |
M0147450 |
ENGMLIPH_00029 |
21755 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
483A>G |
Arg161Arg |
M0147451 |
ENGMLIPH_00029 |
21779 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
507T>A |
Ser169Ser |
M0147452 |
ENGMLIPH_00029 |
21800 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
528C>T |
Asp176Asp |
M0147453 |
ENGMLIPH_00030 |
21981 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
72A>C |
Gly24Gly |
M0147454 |
ENGMLIPH_00030 |
22032 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
123A>T |
Ser41Ser |
M0147455 |
ENGMLIPH_00030 |
22316 |
7 |
Gut |
0.37 |
protein_coding |
missense_variant |
MODERATE |
407A>G |
Asn136Ser |
M0147456 |
ENGMLIPH_00030 |
22332 |
7 |
Gut |
0.37 |
protein_coding |
missense_variant |
MODERATE |
423T>A |
Asp141Glu |
M0147457 |
ENGMLIPH_00030 |
22472 |
7 |
Gut |
0.37 |
protein_coding |
missense_variant |
MODERATE |
563A>G |
Gln188Arg |
M0147458 |
ENGMLIPH_00030 |
22525 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
616G>A |
Glu206Lys |
M0147459 |
ENGMLIPH_00030 |
22532 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
623C>A |
Thr208Asn |
M0147460 |
ENGMLIPH_00030 |
22602 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
693T>C |
Arg231Arg |
M0147461 |
ENGMLIPH_00030 |
22644 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
735A>G |
Lys245Lys |
M0147462 |
ENGMLIPH_00030 |
23100 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
1191A>G |
Glu397Glu |
M0147463 |
ENGMLIPH_00030 |
23190 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
1281T>C |
Asn427Asn |
M0147464 |
ENGMLIPH_00030 |
23208 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
1299T>C |
Ile433Ile |
M0147465 |
ENGMLIPH_00032 |
23788 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
393T>C |
Asn131Asn |
M0147466 |
ENGMLIPH_00032 |
23975 |
7 |
Gut |
0.37 |
protein_coding |
missense_variant |
MODERATE |
580C>A |
His194Asn |
M0147467 |
ENGMLIPH_00032 |
24025 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
630A>G |
Ala210Ala |
M0147468 |
ENGMLIPH_00032 |
24037 |
7 |
Gut |
0.37 |
protein_coding |
synonymous_variant |
LOW |
642A>G |
Val214Val |
M0147469 |
ENGMLIPH_00032 |
24347 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
952T>C |
Leu318Leu |
M0147470 |
ENGMLIPH_00033 |
24489 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
6G>A |
Lys2Lys |
M0147471 |
ENGMLIPH_00033 |
24531 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
48G>T |
Gly16Gly |
M0147472 |
ENGMLIPH_00033 |
24992 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
509C>T |
Thr170Ile |
M0147473 |
ENGMLIPH_00033 |
25134 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
651C>A |
Val217Val |
M0147474 |
ENGMLIPH_00033 |
25200 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
717A>G |
Gly239Gly |
M0147475 |
ENGMLIPH_00033 |
25229 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
746A>T |
Tyr249Phe |
M0147476 |
ENGMLIPH_00033 |
25233 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
750T>C |
Leu250Leu |
M0147477 |
ENGMLIPH_00033 |
25293 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
810T>C |
Ile270Ile |
M0147478 |
ENGMLIPH_00033 |
25367 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
884A>C |
Glu295Ala |
M0147479 |
ENGMLIPH_00033 |
25410 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
927G>A |
Glu309Glu |
M0147480 |
ENGMLIPH_00033 |
25412 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
929A>T |
Tyr310Phe |
M0147481 |
ENGMLIPH_00033 |
25974 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1491A>G |
Lys497Lys |
M0147482 |
ENGMLIPH_00033 |
26118 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1635G>A |
Gln545Gln |
M0147483 |
ENGMLIPH_00033 |
26133 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1650T>C |
Thr550Thr |
M0147484 |
ENGMLIPH_00033 |
26176 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1693C>T |
Leu565Leu |
M0147485 |
ENGMLIPH_00035 |
26642 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
105A>G |
Thr35Thr |
M0147486 |
ENGMLIPH_00035 |
26816 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
279C>T |
Val93Val |
M0147487 |
ENGMLIPH_00035 |
27056 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
519A>G |
Pro173Pro |
M0147488 |
ENGMLIPH_00035 |
27059 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
522G>A |
Glu174Glu |
M0147489 |
ENGMLIPH_00035 |
27146 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
609C>T |
Asp203Asp |
M0147490 |
ENGMLIPH_00035 |
27251 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
714T>A |
Gly238Gly |
M0147491 |
ENGMLIPH_00035 |
27360 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
823C>A |
Arg275Arg |
M0147492 |
ENGMLIPH_00035 |
27438 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
901G>A |
Val301Ile |
M0147493 |
ENGMLIPH_00035 |
27439 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
902T>C |
Val301Ala |
M0147494 |
ENGMLIPH_00035 |
27635 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1098G>A |
Ala366Ala |
M0147495 |
ENGMLIPH_00035 |
27743 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1206A>C |
Ala402Ala |
M0147496 |
ENGMLIPH_00035 |
27797 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1260T>C |
Phe420Phe |
M0147497 |
ENGMLIPH_00036 |
27940 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
89A>G |
Lys30Arg |
M0147498 |
ENGMLIPH_00036 |
27944 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
93A>G |
Glu31Glu |
M0147499 |
ENGMLIPH_00037 |
28195 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
48T>C |
Ser16Ser |
M0147500 |
ENGMLIPH_00037 |
28324 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
177A>G |
Val59Val |
M0147501 |
ENGMLIPH_00037 |
28331 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
184T>C |
Leu62Leu |
M0147502 |
ENGMLIPH_00037 |
28583 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
436G>A |
Glu146Lys |
M0147503 |
ENGMLIPH_00037 |
28622 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
475G>A |
Asp159Asn |
M0147504 |
ENGMLIPH_00037 |
28645 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
498G>A |
Gln166Gln |
M0147505 |
ENGMLIPH_00037 |
28663 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
516C>T |
Asp172Asp |
M0147506 |
ENGMLIPH_00037 |
28834 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
687A>G |
Lys229Lys |
M0147507 |
ENGMLIPH_00037 |
28852 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
705C>A |
Ala235Ala |
M0147508 |
ENGMLIPH_00037 |
29071 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
924A>G |
Arg308Arg |
M0147509 |
ENGMLIPH_00037 |
29212 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1065G>A |
Gln355Gln |
M0147510 |
ENGMLIPH_00037 |
29278 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1131C>A |
Ile377Ile |
M0147511 |
ENGMLIPH_00037 |
29348 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1201C>T |
Leu401Leu |
M0147512 |
ENGMLIPH_00037 |
29351 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1204T>C |
Leu402Leu |
M0147513 |
ENGMLIPH_00037 |
29359 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1212T>A |
Ile404Ile |
M0147514 |
ENGMLIPH_00037 |
29395 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1248T>C |
Pro416Pro |
M0147515 |
ENGMLIPH_00037 |
29497 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1350A>G |
Gln450Gln |
M0147516 |
ENGMLIPH_00037 |
29509 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1362G>A |
Val454Val |
M0147517 |
ENGMLIPH_00037 |
29710 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1563A>G |
Glu521Glu |
M0147518 |
ENGMLIPH_00037 |
29764 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1617G>A |
Lys539Lys |
M0147519 |
ENGMLIPH_00037 |
29797 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1650A>G |
Gly550Gly |
M0147520 |
ENGMLIPH_00038 |
30113 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-28T>C |
None |
M0147521 |
ENGMLIPH_00038 |
30133 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-8A>T |
None |
M0147522 |
ENGMLIPH_00038 |
30195 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
55A>C |
Thr19Pro |
M0147523 |
ENGMLIPH_00038 |
30197 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
57C>T |
Thr19Thr |
M0147524 |
ENGMLIPH_00038 |
30311 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
171T>C |
Asp57Asp |
M0147525 |
ENGMLIPH_00038 |
30353 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
213G>A |
Gln71Gln |
M0147526 |
ENGMLIPH_00038 |
30411 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
271A>G |
Thr91Ala |
M0147527 |
ENGMLIPH_00038 |
30470 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
330G>A |
Arg110Arg |
M0147528 |
ENGMLIPH_00038 |
30485 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
345A>G |
Val115Val |
M0147529 |
ENGMLIPH_00038 |
30609 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
469G>A |
Ala157Thr |
M0147530 |
ENGMLIPH_00039 |
30624 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4A>G |
None |
M0147531 |
ENGMLIPH_00039 |
30690 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
63A>G |
Val21Val |
M0147532 |
ENGMLIPH_00039 |
30707 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
80A>G |
Glu27Gly |
M0147533 |
ENGMLIPH_00039 |
30712 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
85A>G |
Ile29Val |
M0147534 |
ENGMLIPH_00040 |
30780 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-47T>C |
None |
M0147535 |
ENGMLIPH_00040 |
30787 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-40A>G |
None |
M0147536 |
ENGMLIPH_00040 |
30839 |
10 |
Gut |
0.53 |
protein_coding |
missense_variant |
MODERATE |
13T>A |
Phe5Ile |
M0147537 |
ENGMLIPH_00040 |
30847 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
21A>G |
Leu7Leu |
M0147538 |
ENGMLIPH_00040 |
30970 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
144C>T |
Tyr48Tyr |
M0147539 |
ENGMLIPH_00040 |
31057 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
231A>G |
Thr77Thr |
M0147540 |
ENGMLIPH_00041 |
31295 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
25T>C |
Leu9Leu |
M0147541 |
ENGMLIPH_00041 |
31411 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
141A>G |
Leu47Leu |
M0147542 |
ENGMLIPH_00041 |
31436 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
166A>C |
Ile56Leu |
M0147543 |
ENGMLIPH_00041 |
31531 |
9 |
Gut |
0.47 |
protein_coding |
synonymous_variant |
LOW |
261A>G |
Arg87Arg |
M0147544 |
ENGMLIPH_00043 |
31774 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-463A>G |
None |
M0147545 |
ENGMLIPH_00043 |
31834 |
8 |
Gut |
0.42 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-403A>G |
None |
M0147546 |
ENGMLIPH_00042 |
31970 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
105G>A |
Ala35Ala |
M0147547 |
ENGMLIPH_00043 |
32335 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
99T>A |
Ala33Ala |
M0147548 |
ENGMLIPH_00044 |
32775 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
270G>A |
Lys90Lys |
M0147549 |
ENGMLIPH_00045 |
32856 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
39T>C |
Ser13Ser |
M0147550 |
ENGMLIPH_00045 |
33032 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
215G>A |
Arg72Lys |
M0147551 |
ENGMLIPH_00045 |
33483 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
666G>A |
Lys222Lys |
M0147552 |
ENGMLIPH_00045 |
33505 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
688A>G |
Lys230Glu |
M0147553 |
ENGMLIPH_00045 |
33846 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1029A>G |
Lys343Lys |
M0147554 |
ENGMLIPH_00045 |
33903 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
1086T>A |
Pro362Pro |
M0147555 |
ENGMLIPH_00042 |
34189 |
5 |
Gut |
0.26 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2115T>C |
None |
M0147556 |
ENGMLIPH_00042 |
34247 |
5 |
Gut |
0.26 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2173G>T |
None |
M0147557 |
ENGMLIPH_00042 |
34254 |
5 |
Gut |
0.26 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2180T>A |
None |
M0147558 |
ENGMLIPH_00042 |
34273 |
8 |
Gut |
0.42 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2199G>T |
None |
M0147559 |
ENGMLIPH_00042 |
34419 |
8 |
Gut |
0.42 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2345G>A |
None |
M0147560 |
ENGMLIPH_00042 |
34568 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2494A>C |
None |
M0147561 |
ENGMLIPH_00042 |
34574 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2500C>T |
None |
M0147562 |
ENGMLIPH_00042 |
34617 |
9 |
Gut |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2543C>T |
None |
M0147563 |
ENGMLIPH_00046 |
34776 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
114T>C |
Tyr38Tyr |
M0147564 |
ENGMLIPH_00046 |
34828 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
166G>A |
Ala56Thr |
M0147565 |
ENGMLIPH_00046 |
34862 |
9 |
Gut |
0.47 |
protein_coding |
missense_variant |
MODERATE |
200G>A |
Arg67Gln |
M0147566 |
ENGMLIPH_00047 |
34945 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
51G>A |
Gln17Gln |
M0147567 |
ENGMLIPH_00047 |
34959 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
65A>T |
Gln22Leu |
M0147568 |
ENGMLIPH_00047 |
35030 |
8 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
136G>A |
Asp46Asn |
M0147569 |
ENGMLIPH_00047 |
35080 |
8 |
Gut |
0.42 |
protein_coding |
synonymous_variant |
LOW |
186A>G |
Glu62Glu |
M0147570 |
ENGMLIPH_00002 |
2355 |
4 |
Gut |
0.21 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1594T>C |
None |
M0147571 |
ENGMLIPH_00021 |
15596 |
3 |
Gut |
0.16 |
protein_coding |
missense_variant |
MODERATE |
196A>G |
Ile66Val |
M0147572 |
ENGMLIPH_00035 |
26738 |
3 |
Gut |
0.16 |
protein_coding |
missense_variant |
MODERATE |
201G>T |
Gln67His |
M0147573 |
ENGMLIPH_00037 |
29856 |
3 |
Gut |
0.16 |
protein_coding |
missense_variant |
MODERATE |
1709C>T |
Thr570Ile |
M0147574 |
ENGMLIPH_00042 |
32081 |
7 |
Gut |
0.37 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-7A>C |
None |
M0147575 |
ENGMLIPH_00042 |
32091 |
7 |
Gut |
0.37 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-17T>A |
None |
M0147576 |
ENGMLIPH_00042 |
32098 |
7 |
Gut |
0.37 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-24T>C |
None |
M0147577 |
ENGMLIPH_00042 |
32106 |
7 |
Gut |
0.37 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-32G>A |
None |
M0147578 |
ENGMLIPH_00042 |
32122 |
7 |
Gut |
0.37 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-48T>A |
None |
M0147579 |
ENGMLIPH_00042 |
32123 |
7 |
Gut |
0.37 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-49G>A |
None |
M0147580 |
ENGMLIPH_00042 |
32128 |
7 |
Gut |
0.37 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-54G>A |
None |
M0147581 |
ENGMLIPH_00042 |
34259 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2185C>T |
None |
M0147582 |
ENGMLIPH_00042 |
34262 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2188A>G |
None |
M0147583 |
ENGMLIPH_00042 |
34289 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2215C>T |
None |
M0147584 |
ENGMLIPH_00042 |
34290 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2216T>A |
None |
M0147585 |
ENGMLIPH_00042 |
34296 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2222A>G |
None |
M0147586 |
ENGMLIPH_00042 |
34327 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2253A>T |
None |
M0147587 |
ENGMLIPH_00042 |
34472 |
3 |
Gut |
0.16 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2398C>T |
None |
Analysis of virulence factors contributing to bacterial pathogenicity
This table presents virulence factors identified within the plasmid cluster.
Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.
Gene Name |
vf_gene_id |
vf_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
vf_category |
gene_description |
condition |
Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact
This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.
Gene Name |
compound |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
group |
Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents
This table presents antimicrobial resistance genes identified within the plasmid cluster.
Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.
Gene Name |
aro_accession |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
drug_class |
amr_gene_family |
resistance_mechanism |
Analysis of pathogenicity genes to explore pathogen-host interactions
This table presents host pathogen-host interactions within the plasmid cluster.
Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.
Gene Name |
phi_molconn_id |
host gene_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
host_descripton |
disease_name |
function |
phenotype_of_mutant |
Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation
This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.
Gene Name |
cazy_id |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification
This table presents transport proteins within the plasmid cluster.
Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.
Gene Name |
tcid |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
class_field |
class_term |
subclass |
subclass_term |
family |
family_term |