Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C198
  Reference Plasmid   CP103360.1
  Reference Plasmid Size   6784
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0147823 FMFCBNCP_00004 2021 10 Gut 0.91 protein_coding synonymous_variant LOW 381T>G Gly127Gly
M0147824 FMFCBNCP_00003 3058 10 Gut 0.91 protein_coding upstream_gene_variant MODIFIER -1861G>A None
M0147825 FMFCBNCP_00003 3819 11 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2622T>C None
M0147826 FMFCBNCP_00003 3820 11 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2623A>T None
M0147827 FMFCBNCP_00003 3821 11 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2624A>T None
M0147828 FMFCBNCP_00003 3822 11 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2625G>A None
M0147829 FMFCBNCP_00003 3879 11 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2682C>G None
M0147830 FMFCBNCP_00003 3963 9 Gut 0.82 protein_coding upstream_gene_variant MODIFIER -2766C>A None
M0147831 FMFCBNCP_00011 4637 10 Gut 0.91 protein_coding stop_lost&splice_region_variant HIGH 126A>G Ter42Trpext*?
M0147832 FMFCBNCP_00011 4761 11 Gut 1.00 protein_coding start_lost HIGH 2T>G Met1?
M0147833 FMFCBNCP_00002 439 7 Gut 0.64 protein_coding synonymous_variant LOW 105A>G Lys35Lys
M0147834 FMFCBNCP_00009 611 9 Gut 0.82 protein_coding upstream_gene_variant MODIFIER -3508T>G None
M0147835 FMFCBNCP_00004 2147 7 Gut 0.64 protein_coding synonymous_variant LOW 255G>A Leu85Leu
M0147836 FMFCBNCP_00004 2152 7 Gut 0.64 protein_coding missense_variant MODERATE 250A>G Ile84Val
M0147837 FMFCBNCP_00004 2162 7 Gut 0.64 protein_coding synonymous_variant LOW 240A>G Pro80Pro
M0147838 FMFCBNCP_00005 2434 9 Gut 0.82 protein_coding missense_variant MODERATE 563A>G Lys188Arg
M0147839 FMFCBNCP_00005 2442 7 Gut 0.64 protein_coding synonymous_variant LOW 555A>T Thr185Thr
M0147840 FMFCBNCP_00005 2463 7 Gut 0.64 protein_coding synonymous_variant LOW 534G>A Arg178Arg
M0147841 FMFCBNCP_00005 2486 7 Gut 0.64 protein_coding missense_variant MODERATE 511A>G Ile171Val
M0147842 FMFCBNCP_00005 2490 7 Gut 0.64 protein_coding synonymous_variant LOW 507G>A Glu169Glu
M0147843 FMFCBNCP_00005 2529 7 Gut 0.64 protein_coding synonymous_variant LOW 468A>G Glu156Glu
M0147844 FMFCBNCP_00005 2626 7 Gut 0.64 protein_coding missense_variant MODERATE 371A>G Lys124Arg
M0147845 FMFCBNCP_00005 2700 7 Gut 0.64 protein_coding synonymous_variant LOW 297T>C Asn99Asn
M0147846 FMFCBNCP_00005 2739 7 Gut 0.64 protein_coding synonymous_variant LOW 258A>G Lys86Lys
M0147847 FMFCBNCP_00005 2811 7 Gut 0.64 protein_coding synonymous_variant LOW 186C>T Tyr62Tyr
M0147848 FMFCBNCP_00005 2837 7 Gut 0.64 protein_coding synonymous_variant LOW 160T>C Leu54Leu
M0147849 FMFCBNCP_00005 2868 7 Gut 0.64 protein_coding missense_variant MODERATE 129G>A Met43Ile
M0147850 FMFCBNCP_00005 2871 9 Gut 0.82 protein_coding synonymous_variant LOW 126T>C Val42Val
M0147851 FMFCBNCP_00005 2973 7 Gut 0.64 protein_coding synonymous_variant LOW 24T>C Phe8Phe
M0147852 FMFCBNCP_00003 3019 7 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -1822G>A None
M0147853 FMFCBNCP_00003 3050 6 Gut 0.55 protein_coding upstream_gene_variant MODIFIER -1853A>G None
M0147854 FMFCBNCP_00003 3054 6 Gut 0.55 protein_coding upstream_gene_variant MODIFIER -1857A>G None
M0147855 FMFCBNCP_00006 3084 8 Gut 0.73 protein_coding synonymous_variant LOW 109T>C Leu37Leu
M0147856 FMFCBNCP_00006 3157 6 Gut 0.55 protein_coding synonymous_variant LOW 36T>C Tyr12Tyr
M0147857 FMFCBNCP_00008 3651 7 Gut 0.64 protein_coding missense_variant MODERATE 86C>A Ala29Asp
M0147858 FMFCBNCP_00008 3674 7 Gut 0.64 protein_coding synonymous_variant LOW 63C>T Gly21Gly
M0147859 FMFCBNCP_00008 3710 7 Gut 0.64 protein_coding synonymous_variant LOW 27T>C Pro9Pro
M0147860 FMFCBNCP_00003 3834 7 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -2637T>A None
M0147861 FMFCBNCP_00010 4401 8 Gut 0.73 protein_coding missense_variant MODERATE 101G>A Arg34Lys
M0147862 FMFCBNCP_00011 4643 8 Gut 0.73 protein_coding synonymous_variant LOW 120T>C Asn40Asn
M0147863 FMFCBNCP_00011 4650 7 Gut 0.64 protein_coding missense_variant MODERATE 113C>T Thr38Ile
M0147864 FMFCBNCP_00011 4673 7 Gut 0.64 protein_coding synonymous_variant LOW 90A>G Lys30Lys
M0147865 FMFCBNCP_00011 4753 9 Gut 0.82 protein_coding missense_variant MODERATE 10A>G Asn4Asp
M0147866 FMFCBNCP_00003 5052 7 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -3855C>T None
M0147867 FMFCBNCP_00012 5649 7 Gut 0.64 protein_coding synonymous_variant LOW 573T>C Ile191Ile
M0147868 FMFCBNCP_00012 6020 9 Gut 0.82 protein_coding missense_variant MODERATE 944G>A Arg315Lys
M0147869 FMFCBNCP_00003 3886 4 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -2689G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term