Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C208
  Reference Plasmid   CP120664.1
  Reference Plasmid Size   28697
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0148214 HKICKMLD_00023 24140 7 Gut 0.78 protein_coding upstream_gene_variant MODIFIER -4941T>A None
M0148215 HKICKMLD_00023 24166 7 Gut 0.78 protein_coding upstream_gene_variant MODIFIER -4967A>T None
M0148216 HKICKMLD_00023 24171 6 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -4972T>C None
M0148217 HKICKMLD_00023 24172 7 Gut 0.78 protein_coding upstream_gene_variant MODIFIER -4973G>A None
M0148218 HKICKMLD_00023 24190 7 Gut 0.78 protein_coding upstream_gene_variant MODIFIER -4991A>G None
M0148219 HKICKMLD_00024 24240 8 Gut 0.89 protein_coding upstream_gene_variant MODIFIER -4492A>G None
M0148220 HKICKMLD_00024 24278 8 Gut 0.89 protein_coding upstream_gene_variant MODIFIER -4530A>C None
M0148221 HKICKMLD_00029 24330 8 Gut 0.89 protein_coding synonymous_variant LOW 12T>A Ser4Ser
M0148222 HKICKMLD_00029 24372 8 Gut 0.89 protein_coding synonymous_variant LOW 54T>A Arg18Arg
M0148223 HKICKMLD_00029 24447 8 Gut 0.89 protein_coding synonymous_variant LOW 129G>A Gly43Gly
M0148224 HKICKMLD_00029 24517 8 Gut 0.89 protein_coding missense_variant MODERATE 199T>G Ser67Ala
M0148225 HKICKMLD_00024 24547 8 Gut 0.89 protein_coding upstream_gene_variant MODIFIER -4799A>G None
M0148226 HKICKMLD_00030 24683 8 Gut 0.89 protein_coding synonymous_variant LOW 124C>A Arg42Arg
M0148227 HKICKMLD_00030 24794 8 Gut 0.89 protein_coding missense_variant MODERATE 235G>A Asp79Asn
M0148228 HKICKMLD_00031 24849 8 Gut 0.89 protein_coding missense_variant MODERATE 606A>C Arg202Ser
M0148229 HKICKMLD_00031 25155 8 Gut 0.89 protein_coding synonymous_variant LOW 300A>C Thr100Thr
M0148230 HKICKMLD_00031 25263 8 Gut 0.89 protein_coding synonymous_variant LOW 192C>T Tyr64Tyr
M0148231 HKICKMLD_00031 25347 8 Gut 0.89 protein_coding synonymous_variant LOW 108C>T Gly36Gly
M0148232 HKICKMLD_00031 25365 8 Gut 0.89 protein_coding synonymous_variant LOW 90T>C His30His
M0148233 HKICKMLD_00032 25775 8 Gut 0.89 protein_coding synonymous_variant LOW 345A>G Gly115Gly
M0148234 HKICKMLD_00032 25968 8 Gut 0.89 protein_coding missense_variant MODERATE 152T>G Val51Gly
M0148235 HKICKMLD_00033 26248 8 Gut 0.89 protein_coding synonymous_variant LOW 342C>T Gly114Gly
M0148236 HKICKMLD_00033 26302 8 Gut 0.89 protein_coding synonymous_variant LOW 288T>C Tyr96Tyr
M0148237 HKICKMLD_00033 26308 8 Gut 0.89 protein_coding missense_variant MODERATE 282G>A Met94Ile
M0148238 HKICKMLD_00033 26313 8 Gut 0.89 protein_coding missense_variant MODERATE 277A>G Ile93Val
M0148239 HKICKMLD_00033 26314 8 Gut 0.89 protein_coding synonymous_variant LOW 276T>A Val92Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term