Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C213
  Reference Plasmid   CP125216.1
  Reference Plasmid Size   17415
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0059827 KBKLFDGJ_00005 11843 84 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -4851C>A None
M0059828 KBKLFDGJ_00014 15338 83 Skin 0.47 protein_coding missense_variant MODERATE 139G>A Ala47Thr
M0059829 KBKLFDGJ_00014 17012 74 Skin 0.42 protein_coding missense_variant MODERATE 1813G>A Asp605Asn
M0059830 KBKLFDGJ_00001 99 5 Skin 0.03 protein_coding downstream_gene_variant MODIFIER *85C>T None
M0059831 KBKLFDGJ_00001 298 5 Skin 0.03 protein_coding missense_variant MODERATE 1314G>A Met438Ile
M0059832 KBKLFDGJ_00001 405 8 Skin 0.04 protein_coding missense_variant MODERATE 1207C>A Pro403Thr
M0059833 KBKLFDGJ_00001 457 6 Skin 0.03 protein_coding synonymous_variant LOW 1155C>T Ile385Ile
M0059834 KBKLFDGJ_00001 520 6 Skin 0.03 protein_coding synonymous_variant LOW 1092A>G Pro364Pro
M0059835 KBKLFDGJ_00001 700 4 Skin 0.02 protein_coding synonymous_variant LOW 912G>A Val304Val
M0059836 KBKLFDGJ_00001 720 4 Skin 0.02 protein_coding synonymous_variant LOW 892C>T Leu298Leu
M0059837 KBKLFDGJ_00001 760 4 Skin 0.02 protein_coding synonymous_variant LOW 852C>G Pro284Pro
M0059838 KBKLFDGJ_00001 1063 4 Skin 0.02 protein_coding synonymous_variant LOW 549C>T Pro183Pro
M0059839 KBKLFDGJ_00001 1069 4 Skin 0.02 protein_coding synonymous_variant LOW 543C>T Ala181Ala
M0059840 KBKLFDGJ_00001 1135 6 Skin 0.03 protein_coding synonymous_variant LOW 477A>G Pro159Pro
M0059841 KBKLFDGJ_00001 1177 5 Skin 0.03 protein_coding synonymous_variant LOW 435G>T Val145Val
M0059842 KBKLFDGJ_00002 2086 5 Skin 0.03 protein_coding synonymous_variant LOW 30C>T Ala10Ala
M0059843 KBKLFDGJ_00003 2629 6 Skin 0.03 protein_coding missense_variant MODERATE 2687T>C Val896Ala
M0059844 KBKLFDGJ_00006 7825 11 Skin 0.06 protein_coding synonymous_variant LOW 531A>G Arg177Arg
M0059845 KBKLFDGJ_00012 14334 6 Skin 0.03 protein_coding missense_variant MODERATE 395T>G Val132Gly
M0059846 KBKLFDGJ_00005 6713 3 Skin 0.02 protein_coding missense_variant MODERATE 280T>C Ser94Pro
M0059847 KBKLFDGJ_00005 6730 3 Skin 0.02 protein_coding missense_variant MODERATE 263A>G Gln88Arg
M0059848 KBKLFDGJ_00003 10273 3 Skin 0.02 protein_coding upstream_gene_variant MODIFIER -4958C>G None
M0059849 KBKLFDGJ_00003 10285 3 Skin 0.02 protein_coding upstream_gene_variant MODIFIER -4970G>T None
M0059850 KBKLFDGJ_00003 10299 3 Skin 0.02 protein_coding upstream_gene_variant MODIFIER -4984G>A None
M0059851 KBKLFDGJ_00003 10314 3 Skin 0.02 protein_coding upstream_gene_variant MODIFIER -4999C>T None
M0059852 KBKLFDGJ_00009 10371 3 Skin 0.02 protein_coding synonymous_variant LOW 24C>T Asp8Asp
M0059853 KBKLFDGJ_00009 10413 3 Skin 0.02 protein_coding synonymous_variant LOW 66G>C Thr22Thr
M0059854 KBKLFDGJ_00010 11574 3 Skin 0.02 protein_coding missense_variant MODERATE 161A>T Gln54Leu
M0059855 KBKLFDGJ_00005 11820 3 Skin 0.02 protein_coding upstream_gene_variant MODIFIER -4828C>A None
M0059856 KBKLFDGJ_00013 14958 3 Skin 0.02 protein_coding synonymous_variant LOW 192A>G Ala64Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
KBKLFDGJ_00008 Nickel (Ni), Cobalt (Co) 100 1.5e-236 1 436 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term