Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C217
  Reference Plasmid   CP131118.1
  Reference Plasmid Size   145480
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0059864 BHEBJDNA_00003 6369 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -4942G>A None
M0059865 BHEBJDNA_00003 6375 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -4948C>A None
M0059866 BHEBJDNA_00012 8026 4 Skin 0.40 protein_coding missense_variant MODERATE 694A>G Met232Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
BHEBJDNA_00009 ARO:3000347 100 2.21e-151 1 243 1.0000 1.0000 macrolide antibiotic Erm 23S ribosomal RNA methyltransferase antibiotic target alteration
BHEBJDNA_00010 ARO:3002630 100 1.83e-188 1 260 1.0000 1.0000 aminoglycoside antibiotic ANT(9) antibiotic inactivation
BHEBJDNA_00146 ARO:3000375 98.8 4.8e-175 1 245 1.0000 0.9879 macrolide antibiotic Erm 23S ribosomal RNA methyltransferase antibiotic target alteration
BHEBJDNA_00147 ARO:3002647 100 1.07e-198 1 264 1.0000 1.0000 aminoglycoside antibiotic APH(3') antibiotic inactivation
BHEBJDNA_00156 ARO:3002919 100 7.79e-171 1 231 1.0000 1.0000 glycopeptide antibiotic glycopeptide resistance gene cluster antibiotic target alteration
BHEBJDNA_00157 ARO:3002931 99.7 3.45e-268 1 380 1.0000 0.9896 glycopeptide antibiotic vanS antibiotic target alteration
BHEBJDNA_00158 ARO:3002942 100 4.32e-234 1 322 1.0000 1.0000 glycopeptide antibiotic vanH antibiotic target alteration
BHEBJDNA_00159 ARO:3000010 100 1.38e-252 1 343 1.0000 1.0000 glycopeptide antibiotic glycopeptide resistance gene cluster antibiotic target alteration
BHEBJDNA_00160 ARO:3002949 100 2.99e-156 1 202 1.0000 1.0000 glycopeptide antibiotic vanX antibiotic target alteration
BHEBJDNA_00162 ARO:3002647 100 1.07e-198 1 264 1.0000 1.0000 aminoglycoside antibiotic APH(3') antibiotic inactivation
BHEBJDNA_00163 ARO:3000375 98.8 4.8e-175 1 245 1.0000 0.9879 macrolide antibiotic Erm 23S ribosomal RNA methyltransferase antibiotic target alteration






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BHEBJDNA_00155 CCO10203.2|GH1 87.5 5.53e-208 1 329 0.9763 0.8436





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term