Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2801
  Reference Plasmid   DP1806001323_bin.3__NODE_185_length_7332_cov_2.435089
  Reference Plasmid Size   7332
  Reference Plasmid GC Content   0.56
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0060506 DIBJMGGN_00003 2826 3 Skin 0.43 protein_coding missense_variant MODERATE 77T>C Met26Thr
M0060507 DIBJMGGN_00001 3013 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1503C>T None
M0060508 DIBJMGGN_00001 3020 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1510C>G None
M0060509 DIBJMGGN_00001 3022 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1512G>A None
M0060510 DIBJMGGN_00001 3028 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1518G>A None
M0060511 DIBJMGGN_00001 3034 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1524C>T None
M0060512 DIBJMGGN_00004 3056 3 Skin 0.43 protein_coding synonymous_variant LOW 411T>A Ala137Ala
M0060513 DIBJMGGN_00004 3073 4 Skin 0.57 protein_coding missense_variant MODERATE 394A>G Ile132Val
M0060514 DIBJMGGN_00004 3074 3 Skin 0.43 protein_coding synonymous_variant LOW 393G>A Glu131Glu
M0060515 DIBJMGGN_00004 3147 4 Skin 0.57 protein_coding missense_variant MODERATE 320A>C Asp107Ala
M0060516 DIBJMGGN_00004 3149 4 Skin 0.57 protein_coding synonymous_variant LOW 318T>C Asp106Asp
M0060517 DIBJMGGN_00004 3308 3 Skin 0.43 protein_coding synonymous_variant LOW 159C>T Gly53Gly
M0060518 DIBJMGGN_00005 3537 3 Skin 0.43 protein_coding missense_variant MODERATE 404A>G Asn135Ser
M0060519 DIBJMGGN_00005 3589 5 Skin 0.71 protein_coding missense_variant MODERATE 352A>C Lys118Gln
M0060520 DIBJMGGN_00005 3635 5 Skin 0.71 protein_coding synonymous_variant LOW 306G>A Pro102Pro
M0060521 DIBJMGGN_00005 3662 4 Skin 0.57 protein_coding synonymous_variant LOW 279T>C Leu93Leu
M0060522 DIBJMGGN_00005 3689 4 Skin 0.57 protein_coding synonymous_variant LOW 252T>C Ile84Ile
M0060523 DIBJMGGN_00005 3704 3 Skin 0.43 protein_coding synonymous_variant LOW 237G>T Gly79Gly
M0060524 DIBJMGGN_00005 3724 3 Skin 0.43 protein_coding synonymous_variant LOW 217C>T Leu73Leu
M0060525 DIBJMGGN_00005 3743 4 Skin 0.57 protein_coding synonymous_variant LOW 198A>C Ala66Ala
M0060526 DIBJMGGN_00005 3758 3 Skin 0.43 protein_coding synonymous_variant LOW 183A>C Ala61Ala
M0060527 DIBJMGGN_00005 3914 3 Skin 0.43 protein_coding synonymous_variant LOW 27A>G Ala9Ala
M0060528 DIBJMGGN_00001 3956 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -2446C>A None
M0060529 DIBJMGGN_00006 4146 4 Skin 0.57 protein_coding missense_variant MODERATE 127A>G Lys43Glu
M0060530 DIBJMGGN_00006 4227 4 Skin 0.57 protein_coding missense_variant MODERATE 208C>G His70Asp
M0060531 DIBJMGGN_00007 4796 3 Skin 0.43 protein_coding synonymous_variant LOW 345T>C Thr115Thr
M0060532 DIBJMGGN_00007 4826 3 Skin 0.43 protein_coding synonymous_variant LOW 315A>G Ser105Ser
M0060533 DIBJMGGN_00007 4832 3 Skin 0.43 protein_coding synonymous_variant LOW 309T>A Ser103Ser
M0060534 DIBJMGGN_00007 4838 3 Skin 0.43 protein_coding synonymous_variant LOW 303T>C Gly101Gly
M0060535 DIBJMGGN_00007 4940 5 Skin 0.71 protein_coding synonymous_variant LOW 201C>T Arg67Arg
M0060536 DIBJMGGN_00006 4474 3 Skin 0.43 protein_coding missense_variant MODERATE 455T>C Leu152Pro
M0060537 DIBJMGGN_00006 4490 3 Skin 0.43 protein_coding synonymous_variant LOW 471G>A Leu157Leu
M0060538 DIBJMGGN_00006 4493 3 Skin 0.43 protein_coding synonymous_variant LOW 474C>G Pro158Pro
M0060539 DIBJMGGN_00006 4498 3 Skin 0.43 protein_coding missense_variant MODERATE 479G>C Arg160Pro
M0060540 DIBJMGGN_00006 4499 3 Skin 0.43 protein_coding synonymous_variant LOW 480C>G Arg160Arg
M0060541 DIBJMGGN_00006 4500 3 Skin 0.43 protein_coding missense_variant MODERATE 481C>T Pro161Ser
M0060542 DIBJMGGN_00006 4508 3 Skin 0.43 protein_coding missense_variant MODERATE 489T>A Asp163Glu
M0060543 DIBJMGGN_00007 4619 3 Skin 0.43 protein_coding synonymous_variant LOW 522C>G Thr174Thr
M0060544 DIBJMGGN_00007 4628 3 Skin 0.43 protein_coding synonymous_variant LOW 513G>A Arg171Arg
M0060545 DIBJMGGN_00007 5012 3 Skin 0.43 protein_coding synonymous_variant LOW 129T>C Thr43Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term