Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2805
  Reference Plasmid   DP1806001340_bin.2__NODE_170_length_5900_cov_1.283055
  Reference Plasmid Size   5900
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0060570 DOBMEHHL_00001 36 3 Skin 0.43 protein_coding synonymous_variant LOW 30A>G Val10Val
M0060571 DOBMEHHL_00001 618 3 Skin 0.43 protein_coding synonymous_variant LOW 612T>C Tyr204Tyr
M0060572 DOBMEHHL_00001 822 6 Skin 0.86 protein_coding synonymous_variant LOW 816G>A Arg272Arg
M0060573 DOBMEHHL_00002 1120 5 Skin 0.71 protein_coding synonymous_variant LOW 72C>G Arg24Arg
M0060574 DOBMEHHL_00002 1129 5 Skin 0.71 protein_coding synonymous_variant LOW 81T>C Ser27Ser
M0060575 DOBMEHHL_00003 1733 5 Skin 0.71 protein_coding missense_variant MODERATE 181A>G Arg61Gly
M0060576 DOBMEHHL_00003 1735 5 Skin 0.71 protein_coding missense_variant MODERATE 183G>C Arg61Ser
M0060577 DOBMEHHL_00005 2376 5 Skin 0.71 protein_coding synonymous_variant LOW 477G>C Leu159Leu
M0060578 DOBMEHHL_00005 2379 5 Skin 0.71 protein_coding synonymous_variant LOW 474C>G Ala158Ala
M0060579 DOBMEHHL_00005 2382 5 Skin 0.71 protein_coding synonymous_variant LOW 471T>C Ile157Ile
M0060580 DOBMEHHL_00005 2530 3 Skin 0.43 protein_coding missense_variant MODERATE 323T>A Val108Glu
M0060581 DOBMEHHL_00005 2834 3 Skin 0.43 protein_coding missense_variant MODERATE 19C>T Pro7Ser
M0060582 DOBMEHHL_00005 2835 3 Skin 0.43 protein_coding synonymous_variant LOW 18T>C Ile6Ile
M0060583 DOBMEHHL_00005 2847 4 Skin 0.57 protein_coding synonymous_variant LOW 6T>C Thr2Thr
M0060584 DOBMEHHL_00006 3145 5 Skin 0.71 protein_coding synonymous_variant LOW 258A>G Gly86Gly
M0060585 DOBMEHHL_00006 3313 5 Skin 0.71 protein_coding synonymous_variant LOW 90T>C His30His
M0060586 DOBMEHHL_00006 3349 5 Skin 0.71 protein_coding synonymous_variant LOW 54G>C Val18Val
M0060587 DOBMEHHL_00006 3351 5 Skin 0.71 protein_coding missense_variant MODERATE 52G>A Val18Met
M0060588 DOBMEHHL_00007 3712 3 Skin 0.43 protein_coding missense_variant MODERATE 851C>A Ala284Glu
M0060589 DOBMEHHL_00007 3873 4 Skin 0.57 protein_coding synonymous_variant LOW 690T>C His230His
M0060590 DOBMEHHL_00007 3894 3 Skin 0.43 protein_coding synonymous_variant LOW 669C>T Leu223Leu
M0060591 DOBMEHHL_00007 3896 3 Skin 0.43 protein_coding missense_variant MODERATE 667C>G Leu223Val
M0060592 DOBMEHHL_00007 3960 3 Skin 0.43 protein_coding synonymous_variant LOW 603C>G Thr201Thr
M0060593 DOBMEHHL_00007 4134 3 Skin 0.43 protein_coding synonymous_variant LOW 429C>T Ser143Ser
M0060594 DOBMEHHL_00007 4242 3 Skin 0.43 protein_coding synonymous_variant LOW 321G>A Gln107Gln
M0060595 DOBMEHHL_00007 4308 4 Skin 0.57 protein_coding synonymous_variant LOW 255C>T Val85Val
M0060596 DOBMEHHL_00007 4431 4 Skin 0.57 protein_coding synonymous_variant LOW 132A>G Gly44Gly
M0060597 DOBMEHHL_00009 5281 3 Skin 0.43 protein_coding synonymous_variant LOW 273A>G Arg91Arg
M0060598 DOBMEHHL_00001 744 4 Skin 0.57 protein_coding synonymous_variant LOW 738G>A Gly246Gly
M0060599 DOBMEHHL_00001 778 4 Skin 0.57 protein_coding missense_variant MODERATE 772G>C Val258Leu
M0060600 DOBMEHHL_00006 3199 4 Skin 0.57 protein_coding synonymous_variant LOW 204T>C Gly68Gly
M0060601 DOBMEHHL_00003 1714 3 Skin 0.43 protein_coding synonymous_variant LOW 162C>T Ala54Ala
M0060602 DOBMEHHL_00005 2349 3 Skin 0.43 protein_coding synonymous_variant LOW 504G>A Lys168Lys
M0060603 DOBMEHHL_00005 2724 3 Skin 0.43 protein_coding synonymous_variant LOW 129T>C Pro43Pro
M0060604 DOBMEHHL_00007 4236 3 Skin 0.43 protein_coding synonymous_variant LOW 327G>A Ser109Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term