Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2811
  Reference Plasmid   DP1806001401_bin.10__NODE_50_length_14364_cov_1.879005
  Reference Plasmid Size   14364
  Reference Plasmid GC Content   0.59
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0061363 GJGHBIPA_00010 9024 50 Skin 0.63 protein_coding missense_variant MODERATE 979G>C Asp327His
M0061364 GJGHBIPA_00013 12124 4 Skin 0.05 protein_coding synonymous_variant LOW 231C>T His77His
M0061365 GJGHBIPA_00009 13226 46 Skin 0.58 protein_coding upstream_gene_variant MODIFIER -4708A>G None
M0061366 GJGHBIPA_00015 13252 30 Skin 0.38 protein_coding synonymous_variant LOW 249T>C Pro83Pro
M0061367 GJGHBIPA_00015 13257 36 Skin 0.46 protein_coding missense_variant MODERATE 244A>G Asn82Asp
M0061368 GJGHBIPA_00015 13261 36 Skin 0.46 protein_coding synonymous_variant LOW 240C>T Pro80Pro
M0061369 GJGHBIPA_00015 13318 32 Skin 0.41 protein_coding synonymous_variant LOW 183A>G Glu61Glu
M0061370 GJGHBIPA_00009 8336 54 Skin 0.68 protein_coding synonymous_variant LOW 183A>T Leu61Leu
M0061371 GJGHBIPA_00010 9547 24 Skin 0.30 protein_coding synonymous_variant LOW 456T>C Asn152Asn
M0061372 GJGHBIPA_00007 11687 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4955A>G None
M0061373 GJGHBIPA_00009 13048 11 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4530A>G None
M0061374 GJGHBIPA_00009 13061 11 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4543G>T None
M0061375 GJGHBIPA_00004 3203 7 Skin 0.09 protein_coding synonymous_variant LOW 240G>C Ala80Ala
M0061376 GJGHBIPA_00004 3323 5 Skin 0.06 protein_coding synonymous_variant LOW 360G>A Pro120Pro
M0061377 GJGHBIPA_00004 3395 7 Skin 0.09 protein_coding synonymous_variant LOW 432C>T Asp144Asp
M0061378 GJGHBIPA_00004 3434 6 Skin 0.08 protein_coding synonymous_variant LOW 471G>A Lys157Lys
M0061379 GJGHBIPA_00004 3536 8 Skin 0.10 protein_coding synonymous_variant LOW 573G>A Ala191Ala
M0061380 GJGHBIPA_00004 3548 7 Skin 0.09 protein_coding synonymous_variant LOW 585T>C Tyr195Tyr
M0061381 GJGHBIPA_00004 3580 7 Skin 0.09 protein_coding missense_variant MODERATE 617G>A Arg206Gln
M0061382 GJGHBIPA_00004 3586 7 Skin 0.09 protein_coding missense_variant MODERATE 623A>G His208Arg
M0061383 GJGHBIPA_00004 3764 7 Skin 0.09 protein_coding synonymous_variant LOW 801C>G Leu267Leu
M0061384 GJGHBIPA_00004 3791 7 Skin 0.09 protein_coding synonymous_variant LOW 828G>A Gly276Gly
M0061385 GJGHBIPA_00003 3875 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1013G>A None
M0061386 GJGHBIPA_00003 3881 6 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1019A>G None
M0061387 GJGHBIPA_00003 3899 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1037T>C None
M0061388 GJGHBIPA_00003 3900 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1038C>T None
M0061389 GJGHBIPA_00005 3935 7 Skin 0.09 protein_coding missense_variant MODERATE 1220T>A Val407Asp
M0061390 GJGHBIPA_00005 3954 6 Skin 0.08 protein_coding synonymous_variant LOW 1201C>T Leu401Leu
M0061391 GJGHBIPA_00005 4098 13 Skin 0.16 protein_coding missense_variant MODERATE 1057T>C Tyr353His
M0061392 GJGHBIPA_00005 4144 4 Skin 0.05 protein_coding synonymous_variant LOW 1011C>T Asn337Asn
M0061393 GJGHBIPA_00005 4150 4 Skin 0.05 protein_coding synonymous_variant LOW 1005T>C Ser335Ser
M0061394 GJGHBIPA_00005 4171 4 Skin 0.05 protein_coding missense_variant MODERATE 984T>G Asp328Glu
M0061395 GJGHBIPA_00005 4215 20 Skin 0.25 protein_coding missense_variant MODERATE 940A>G Asn314Asp
M0061396 GJGHBIPA_00005 4555 3 Skin 0.04 protein_coding synonymous_variant LOW 600C>T Gly200Gly
M0061397 GJGHBIPA_00005 4564 3 Skin 0.04 protein_coding synonymous_variant LOW 591A>G Leu197Leu
M0061398 GJGHBIPA_00005 4567 3 Skin 0.04 protein_coding synonymous_variant LOW 588T>C Val196Val
M0061399 GJGHBIPA_00005 4697 9 Skin 0.11 protein_coding missense_variant MODERATE 458C>T Ser153Phe
M0061400 GJGHBIPA_00005 4714 10 Skin 0.13 protein_coding synonymous_variant LOW 441C>T Asn147Asn
M0061401 GJGHBIPA_00005 4743 10 Skin 0.13 protein_coding synonymous_variant LOW 412T>C Leu138Leu
M0061402 GJGHBIPA_00005 4750 10 Skin 0.13 protein_coding synonymous_variant LOW 405T>C Ala135Ala
M0061403 GJGHBIPA_00005 4753 10 Skin 0.13 protein_coding synonymous_variant LOW 402A>G Leu134Leu
M0061404 GJGHBIPA_00005 4822 21 Skin 0.27 protein_coding synonymous_variant LOW 333T>C Pro111Pro
M0061405 GJGHBIPA_00005 4861 10 Skin 0.13 protein_coding synonymous_variant LOW 294T>C Asn98Asn
M0061406 GJGHBIPA_00005 4893 10 Skin 0.13 protein_coding missense_variant MODERATE 262C>T His88Tyr
M0061407 GJGHBIPA_00005 4897 10 Skin 0.13 protein_coding missense_variant MODERATE 258G>T Lys86Asn
M0061408 GJGHBIPA_00005 4906 10 Skin 0.13 protein_coding synonymous_variant LOW 249C>T Cys83Cys
M0061409 GJGHBIPA_00005 5071 11 Skin 0.14 protein_coding synonymous_variant LOW 84A>G Glu28Glu
M0061410 GJGHBIPA_00005 5153 11 Skin 0.14 protein_coding start_lost HIGH 2T>C Met1?
M0061411 GJGHBIPA_00006 5180 11 Skin 0.14 protein_coding synonymous_variant LOW 744A>G Leu248Leu
M0061412 GJGHBIPA_00006 5255 12 Skin 0.15 protein_coding synonymous_variant LOW 669C>T Val223Val
M0061413 GJGHBIPA_00006 5257 12 Skin 0.15 protein_coding missense_variant MODERATE 667G>C Val223Leu
M0061414 GJGHBIPA_00006 5300 11 Skin 0.14 protein_coding synonymous_variant LOW 624A>T Leu208Leu
M0061415 GJGHBIPA_00006 5333 12 Skin 0.15 protein_coding synonymous_variant LOW 591C>T Arg197Arg
M0061416 GJGHBIPA_00006 5372 11 Skin 0.14 protein_coding synonymous_variant LOW 552C>T Ala184Ala
M0061417 GJGHBIPA_00006 5416 12 Skin 0.15 protein_coding missense_variant MODERATE 508G>C Val170Leu
M0061418 GJGHBIPA_00006 5423 12 Skin 0.15 protein_coding synonymous_variant LOW 501T>C Asp167Asp
M0061419 GJGHBIPA_00006 5480 11 Skin 0.14 protein_coding synonymous_variant LOW 444C>T Phe148Phe
M0061420 GJGHBIPA_00006 5489 11 Skin 0.14 protein_coding synonymous_variant LOW 435A>G Pro145Pro
M0061421 GJGHBIPA_00006 5492 11 Skin 0.14 protein_coding synonymous_variant LOW 432C>T Phe144Phe
M0061422 GJGHBIPA_00006 5498 12 Skin 0.15 protein_coding synonymous_variant LOW 426T>C Ser142Ser
M0061423 GJGHBIPA_00006 5553 10 Skin 0.13 protein_coding missense_variant MODERATE 371A>G Lys124Arg
M0061424 GJGHBIPA_00006 5564 11 Skin 0.14 protein_coding synonymous_variant LOW 360T>C Arg120Arg
M0061425 GJGHBIPA_00006 5609 10 Skin 0.13 protein_coding synonymous_variant LOW 315G>A Ala105Ala
M0061426 GJGHBIPA_00006 5636 11 Skin 0.14 protein_coding synonymous_variant LOW 288C>T Leu96Leu
M0061427 GJGHBIPA_00006 5645 10 Skin 0.13 protein_coding synonymous_variant LOW 279G>A Arg93Arg
M0061428 GJGHBIPA_00006 5699 10 Skin 0.13 protein_coding synonymous_variant LOW 225C>T Ala75Ala
M0061429 GJGHBIPA_00006 5715 10 Skin 0.13 protein_coding missense_variant MODERATE 209C>A Thr70Lys
M0061430 GJGHBIPA_00006 5738 12 Skin 0.15 protein_coding synonymous_variant LOW 186G>A Ser62Ser
M0061431 GJGHBIPA_00006 5766 13 Skin 0.16 protein_coding missense_variant MODERATE 158C>T Ala53Val
M0061432 GJGHBIPA_00006 5771 12 Skin 0.15 protein_coding synonymous_variant LOW 153C>T Leu51Leu
M0061433 GJGHBIPA_00006 5804 12 Skin 0.15 protein_coding synonymous_variant LOW 120C>T Val40Val
M0061434 GJGHBIPA_00006 5894 17 Skin 0.22 protein_coding synonymous_variant LOW 30G>A Leu10Leu
M0061435 GJGHBIPA_00007 5945 16 Skin 0.20 protein_coding missense_variant MODERATE 788C>T Thr263Met
M0061436 GJGHBIPA_00007 5956 17 Skin 0.22 protein_coding synonymous_variant LOW 777C>T Val259Val
M0061437 GJGHBIPA_00007 5986 17 Skin 0.22 protein_coding synonymous_variant LOW 747C>T Arg249Arg
M0061438 GJGHBIPA_00007 6024 15 Skin 0.19 protein_coding missense_variant MODERATE 709G>A Asp237Asn
M0061439 GJGHBIPA_00007 6040 15 Skin 0.19 protein_coding synonymous_variant LOW 693A>G Glu231Glu
M0061440 GJGHBIPA_00007 6055 4 Skin 0.05 protein_coding synonymous_variant LOW 678G>C Ser226Ser
M0061441 GJGHBIPA_00007 6184 22 Skin 0.28 protein_coding synonymous_variant LOW 549C>T Val183Val
M0061442 GJGHBIPA_00007 6211 23 Skin 0.29 protein_coding synonymous_variant LOW 522T>C Cys174Cys
M0061443 GJGHBIPA_00007 6214 23 Skin 0.29 protein_coding missense_variant MODERATE 519T>G Ile173Met
M0061444 GJGHBIPA_00007 6331 24 Skin 0.30 protein_coding synonymous_variant LOW 402G>A Gln134Gln
M0061445 GJGHBIPA_00007 6353 20 Skin 0.25 protein_coding missense_variant MODERATE 380G>A Arg127His
M0061446 GJGHBIPA_00007 6385 22 Skin 0.28 protein_coding synonymous_variant LOW 348T>C His116His
M0061447 GJGHBIPA_00007 6397 20 Skin 0.25 protein_coding synonymous_variant LOW 336A>G Val112Val
M0061448 GJGHBIPA_00007 6403 20 Skin 0.25 protein_coding synonymous_variant LOW 330G>C Gly110Gly
M0061449 GJGHBIPA_00007 6478 24 Skin 0.30 protein_coding synonymous_variant LOW 255C>T Gly85Gly
M0061450 GJGHBIPA_00007 6500 23 Skin 0.29 protein_coding missense_variant MODERATE 233A>G His78Arg
M0061451 GJGHBIPA_00007 6511 23 Skin 0.29 protein_coding synonymous_variant LOW 222T>A Gly74Gly
M0061452 GJGHBIPA_00007 6516 23 Skin 0.29 protein_coding missense_variant MODERATE 217C>G Leu73Val
M0061453 GJGHBIPA_00007 6517 23 Skin 0.29 protein_coding synonymous_variant LOW 216A>G Leu72Leu
M0061454 GJGHBIPA_00007 6574 24 Skin 0.30 protein_coding synonymous_variant LOW 159C>T Gly53Gly
M0061455 GJGHBIPA_00007 6634 26 Skin 0.33 protein_coding synonymous_variant LOW 99A>G Arg33Arg
M0061456 GJGHBIPA_00007 6646 26 Skin 0.33 protein_coding missense_variant MODERATE 87A>C Glu29Asp
M0061457 GJGHBIPA_00007 6673 28 Skin 0.35 protein_coding synonymous_variant LOW 60T>C Ala20Ala
M0061458 GJGHBIPA_00007 6685 28 Skin 0.35 protein_coding synonymous_variant LOW 48T>C His16His
M0061459 GJGHBIPA_00007 6691 27 Skin 0.34 protein_coding synonymous_variant LOW 42A>G Gly14Gly
M0061460 GJGHBIPA_00008 6786 22 Skin 0.28 protein_coding synonymous_variant LOW 759T>C Leu253Leu
M0061461 GJGHBIPA_00008 7353 43 Skin 0.54 protein_coding synonymous_variant LOW 192A>G Val64Val
M0061462 GJGHBIPA_00008 7539 6 Skin 0.08 protein_coding synonymous_variant LOW 6A>G Lys2Lys
M0061463 GJGHBIPA_00010 8665 6 Skin 0.08 protein_coding missense_variant MODERATE 1338G>C Met446Ile
M0061464 GJGHBIPA_00010 9392 21 Skin 0.27 protein_coding missense_variant MODERATE 611G>A Arg204Gln
M0061465 GJGHBIPA_00010 9400 20 Skin 0.25 protein_coding synonymous_variant LOW 603G>C Pro201Pro
M0061466 GJGHBIPA_00010 9418 22 Skin 0.28 protein_coding synonymous_variant LOW 585T>C His195His
M0061467 GJGHBIPA_00010 9424 21 Skin 0.27 protein_coding synonymous_variant LOW 579A>C Pro193Pro
M0061468 GJGHBIPA_00010 9451 22 Skin 0.28 protein_coding synonymous_variant LOW 552A>G Gly184Gly
M0061469 GJGHBIPA_00010 9490 21 Skin 0.27 protein_coding synonymous_variant LOW 513G>T Pro171Pro
M0061470 GJGHBIPA_00010 9517 19 Skin 0.24 protein_coding synonymous_variant LOW 486C>T Ala162Ala
M0061471 GJGHBIPA_00010 9522 6 Skin 0.08 protein_coding synonymous_variant LOW 481C>T Leu161Leu
M0061472 GJGHBIPA_00010 9613 24 Skin 0.30 protein_coding synonymous_variant LOW 390A>G Ala130Ala
M0061473 GJGHBIPA_00010 9650 34 Skin 0.43 protein_coding missense_variant MODERATE 353T>G Leu118Arg
M0061474 GJGHBIPA_00010 9700 17 Skin 0.22 protein_coding synonymous_variant LOW 303C>T Phe101Phe
M0061475 GJGHBIPA_00010 9735 21 Skin 0.27 protein_coding synonymous_variant LOW 268A>C Arg90Arg
M0061476 GJGHBIPA_00010 9738 19 Skin 0.24 protein_coding synonymous_variant LOW 265C>T Leu89Leu
M0061477 GJGHBIPA_00010 9784 17 Skin 0.22 protein_coding synonymous_variant LOW 219G>A Lys73Lys
M0061478 GJGHBIPA_00010 9798 19 Skin 0.24 protein_coding missense_variant MODERATE 205A>G Asn69Asp
M0061479 GJGHBIPA_00006 10318 25 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -4395G>A None
M0061480 GJGHBIPA_00006 10607 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4684C>G None
M0061481 GJGHBIPA_00007 11712 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -4980C>T None
M0061482 GJGHBIPA_00008 11862 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -4318C>T None
M0061483 GJGHBIPA_00008 12301 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4757G>C None
M0061484 GJGHBIPA_00008 12355 48 Skin 0.61 protein_coding upstream_gene_variant MODIFIER -4811T>C None
M0061485 GJGHBIPA_00014 12774 34 Skin 0.43 protein_coding missense_variant MODERATE 269A>G His90Arg
M0061486 GJGHBIPA_00009 13176 37 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -4658C>G None
M0061487 GJGHBIPA_00002 1607 4 Skin 0.05 protein_coding synonymous_variant LOW 978G>A Leu326Leu
M0061488 GJGHBIPA_00002 1614 4 Skin 0.05 protein_coding missense_variant MODERATE 985A>G Thr329Ala
M0061489 GJGHBIPA_00003 2766 3 Skin 0.04 protein_coding missense_variant MODERATE 97A>C Ser33Arg
M0061490 GJGHBIPA_00010 8997 8 Skin 0.10 protein_coding missense_variant MODERATE 1006C>T Leu336Phe
M0061491 GJGHBIPA_00010 9443 13 Skin 0.16 protein_coding missense_variant MODERATE 560T>G Val187Gly
M0061492 GJGHBIPA_00012 10971 8 Skin 0.10 protein_coding missense_variant MODERATE 265G>A Ala89Thr
M0061493 GJGHBIPA_00009 13141 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4623C>T None
M0061494 GJGHBIPA_00008 7423 4 Skin 0.05 protein_coding missense_variant MODERATE 122T>C Met41Thr
M0061495 GJGHBIPA_00009 7923 5 Skin 0.06 protein_coding missense_variant MODERATE 596C>T Thr199Met
M0061496 GJGHBIPA_00012 10884 4 Skin 0.05 protein_coding synonymous_variant LOW 178T>C Leu60Leu
M0061497 GJGHBIPA_00016 13670 12 Skin 0.15 protein_coding missense_variant MODERATE 436C>T Arg146Trp
M0061498 GJGHBIPA_00016 13691 12 Skin 0.15 protein_coding synonymous_variant LOW 415C>T Leu139Leu
M0061499 GJGHBIPA_00010 9421 4 Skin 0.05 protein_coding synonymous_variant LOW 582A>G Gly194Gly
M0061500 GJGHBIPA_00008 7446 3 Skin 0.04 protein_coding synonymous_variant LOW 99T>A Leu33Leu
M0061501 GJGHBIPA_00005 4491 3 Skin 0.04 protein_coding missense_variant MODERATE 664A>G Ile222Val
M0061502 GJGHBIPA_00014 12687 6 Skin 0.08 protein_coding missense_variant MODERATE 356A>C Asn119Thr
M0061503 GJGHBIPA_00005 4382 4 Skin 0.05 protein_coding missense_variant MODERATE 773A>G Asn258Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term