Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2812
  Reference Plasmid   DP1806001413_bin.6__NODE_948_length_4400_cov_0.923274
  Reference Plasmid Size   4400
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0061504 GJBIPAJG_00003 1808 4 Skin 0.25 protein_coding synonymous_variant LOW 627A>G Leu209Leu
M0061505 GJBIPAJG_00003 1901 4 Skin 0.25 protein_coding synonymous_variant LOW 534C>T Tyr178Tyr
M0061506 GJBIPAJG_00003 1964 4 Skin 0.25 protein_coding synonymous_variant LOW 471C>T Pro157Pro
M0061507 GJBIPAJG_00003 1982 4 Skin 0.25 protein_coding missense_variant MODERATE 453A>T Lys151Asn
M0061508 GJBIPAJG_00003 2019 4 Skin 0.25 protein_coding missense_variant MODERATE 416T>C Met139Thr
M0061509 GJBIPAJG_00003 2114 4 Skin 0.25 protein_coding synonymous_variant LOW 321T>C Gly107Gly
M0061510 GJBIPAJG_00003 2225 4 Skin 0.25 protein_coding synonymous_variant LOW 210C>T Arg70Arg
M0061511 GJBIPAJG_00003 2248 4 Skin 0.25 protein_coding missense_variant MODERATE 187G>A Val63Met
M0061512 GJBIPAJG_00003 2252 4 Skin 0.25 protein_coding synonymous_variant LOW 183T>C His61His
M0061513 GJBIPAJG_00003 2264 4 Skin 0.25 protein_coding synonymous_variant LOW 171C>T Leu57Leu
M0061514 GJBIPAJG_00003 2276 4 Skin 0.25 protein_coding synonymous_variant LOW 159G>A Glu53Glu
M0061515 GJBIPAJG_00003 2330 4 Skin 0.25 protein_coding synonymous_variant LOW 105A>G Gly35Gly
M0061516 GJBIPAJG_00003 2400 4 Skin 0.25 protein_coding missense_variant MODERATE 35T>C Val12Ala
M0061517 GJBIPAJG_00004 2476 4 Skin 0.25 protein_coding missense_variant MODERATE 190T>C Ser64Pro
M0061518 GJBIPAJG_00004 2514 4 Skin 0.25 protein_coding stop_gained HIGH 152G>A Trp51*
M0061519 GJBIPAJG_00004 2543 6 Skin 0.38 protein_coding missense_variant MODERATE 123G>A Met41Ile
M0061520 GJBIPAJG_00004 2597 4 Skin 0.25 protein_coding synonymous_variant LOW 69T>C Asp23Asp
M0061521 GJBIPAJG_00002 2684 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1227A>C None
M0061522 GJBIPAJG_00002 2690 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1233A>G None
M0061523 GJBIPAJG_00002 2784 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1327A>G None
M0061524 GJBIPAJG_00002 2858 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1401A>G None
M0061525 GJBIPAJG_00005 2962 4 Skin 0.25 protein_coding synonymous_variant LOW 27C>T Val9Val
M0061526 GJBIPAJG_00005 2992 4 Skin 0.25 protein_coding synonymous_variant LOW 57T>C Ile19Ile
M0061527 GJBIPAJG_00005 3014 4 Skin 0.25 protein_coding synonymous_variant LOW 79T>C Leu27Leu
M0061528 GJBIPAJG_00005 3105 4 Skin 0.25 protein_coding missense_variant MODERATE 170T>C Val57Ala
M0061529 GJBIPAJG_00005 3142 4 Skin 0.25 protein_coding synonymous_variant LOW 207G>A Gln69Gln
M0061530 GJBIPAJG_00005 3197 4 Skin 0.25 protein_coding synonymous_variant LOW 262C>T Leu88Leu
M0061531 GJBIPAJG_00005 3273 4 Skin 0.25 protein_coding missense_variant MODERATE 338A>G His113Arg
M0061532 GJBIPAJG_00005 3343 4 Skin 0.25 protein_coding synonymous_variant LOW 408A>G Leu136Leu
M0061533 GJBIPAJG_00005 3371 4 Skin 0.25 protein_coding missense_variant MODERATE 436G>T Ala146Ser
M0061534 GJBIPAJG_00005 3550 4 Skin 0.25 protein_coding synonymous_variant LOW 615C>G Ser205Ser
M0061535 GJBIPAJG_00005 3619 4 Skin 0.25 protein_coding synonymous_variant LOW 684G>A Val228Val
M0061536 GJBIPAJG_00005 3622 4 Skin 0.25 protein_coding synonymous_variant LOW 687T>C Val229Val
M0061537 GJBIPAJG_00005 3649 4 Skin 0.25 protein_coding synonymous_variant LOW 714T>C Gly238Gly
M0061538 GJBIPAJG_00006 3702 4 Skin 0.25 protein_coding missense_variant MODERATE 412T>C Ser138Pro
M0061539 GJBIPAJG_00006 3715 4 Skin 0.25 protein_coding synonymous_variant LOW 399T>G Ala133Ala
M0061540 GJBIPAJG_00006 3778 4 Skin 0.25 protein_coding missense_variant MODERATE 336A>C Arg112Ser
M0061541 GJBIPAJG_00006 3780 4 Skin 0.25 protein_coding missense_variant MODERATE 334A>G Arg112Gly
M0061542 GJBIPAJG_00006 3860 4 Skin 0.25 protein_coding missense_variant MODERATE 254T>G Val85Gly
M0061543 GJBIPAJG_00006 3933 4 Skin 0.25 protein_coding missense_variant MODERATE 181G>A Ala61Thr
M0061544 GJBIPAJG_00006 3963 4 Skin 0.25 protein_coding missense_variant MODERATE 151A>G Asn51Asp
M0061545 GJBIPAJG_00006 4002 4 Skin 0.25 protein_coding stop_gained HIGH 112C>T Gln38*
M0061546 GJBIPAJG_00006 4084 4 Skin 0.25 protein_coding synonymous_variant LOW 30T>C Gly10Gly
M0061547 GJBIPAJG_00002 4149 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -2692C>T None
M0061548 GJBIPAJG_00002 4266 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -2809T>G None
M0061549 GJBIPAJG_00002 4317 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -2860A>G None
M0061550 GJBIPAJG_00001 507 4 Skin 0.25 protein_coding missense_variant MODERATE 314A>G Asp105Gly
M0061551 GJBIPAJG_00001 568 4 Skin 0.25 protein_coding synonymous_variant LOW 375C>T Arg125Arg
M0061552 GJBIPAJG_00003 2354 5 Skin 0.31 protein_coding synonymous_variant LOW 81G>A Gln27Gln
M0061553 GJBIPAJG_00002 2453 5 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -996A>G None
M0061554 GJBIPAJG_00005 3080 5 Skin 0.31 protein_coding missense_variant MODERATE 145C>T Pro49Ser
M0061555 GJBIPAJG_00003 1805 3 Skin 0.19 protein_coding synonymous_variant LOW 630C>T Ser210Ser
M0061556 GJBIPAJG_00001 26 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -168G>A None
M0061557 GJBIPAJG_00001 47 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -147T>C None
M0061558 GJBIPAJG_00001 53 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -141C>T None
M0061559 GJBIPAJG_00001 107 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -87G>A None
M0061560 GJBIPAJG_00001 113 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -81C>T None
M0061561 GJBIPAJG_00001 201 3 Skin 0.19 protein_coding missense_variant MODERATE 8A>C Glu3Ala
M0061562 GJBIPAJG_00001 325 3 Skin 0.19 protein_coding synonymous_variant LOW 132A>G Val44Val
M0061563 GJBIPAJG_00001 373 3 Skin 0.19 protein_coding synonymous_variant LOW 180C>T Gly60Gly
M0061564 GJBIPAJG_00001 403 3 Skin 0.19 protein_coding synonymous_variant LOW 210T>C Ala70Ala
M0061565 GJBIPAJG_00001 415 3 Skin 0.19 protein_coding synonymous_variant LOW 222C>T Thr74Thr
M0061566 GJBIPAJG_00001 460 3 Skin 0.19 protein_coding synonymous_variant LOW 267G>T Thr89Thr
M0061567 GJBIPAJG_00001 471 3 Skin 0.19 protein_coding missense_variant MODERATE 278A>G Asp93Gly
M0061568 GJBIPAJG_00001 481 3 Skin 0.19 protein_coding synonymous_variant LOW 288T>C Ser96Ser
M0061569 GJBIPAJG_00001 641 3 Skin 0.19 protein_coding missense_variant MODERATE 448G>A Ala150Thr
M0061570 GJBIPAJG_00001 656 3 Skin 0.19 protein_coding missense_variant MODERATE 463A>C Asn155His
M0061571 GJBIPAJG_00001 728 3 Skin 0.19 protein_coding missense_variant MODERATE 535A>G Lys179Glu
M0061572 GJBIPAJG_00001 744 3 Skin 0.19 protein_coding missense_variant MODERATE 551A>G Asn184Ser
M0061573 GJBIPAJG_00005 773 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -2163G>A None
M0061574 GJBIPAJG_00002 866 3 Skin 0.19 protein_coding missense_variant MODERATE 592G>A Ala198Thr
M0061575 GJBIPAJG_00002 870 3 Skin 0.19 protein_coding synonymous_variant LOW 588T>C Pro196Pro
M0061576 GJBIPAJG_00002 938 3 Skin 0.19 protein_coding missense_variant MODERATE 520T>C Tyr174His
M0061577 GJBIPAJG_00002 1044 3 Skin 0.19 protein_coding synonymous_variant LOW 414C>T Pro138Pro
M0061578 GJBIPAJG_00002 1287 3 Skin 0.19 protein_coding synonymous_variant LOW 171A>G Ala57Ala
M0061579 GJBIPAJG_00002 1361 3 Skin 0.19 protein_coding missense_variant MODERATE 97G>A Ala33Thr
M0061580 GJBIPAJG_00002 1387 3 Skin 0.19 protein_coding missense_variant MODERATE 71G>A Gly24Asp
M0061581 GJBIPAJG_00002 1408 3 Skin 0.19 protein_coding missense_variant MODERATE 50C>T Ala17Val
M0061582 GJBIPAJG_00002 1422 3 Skin 0.19 protein_coding synonymous_variant LOW 36C>T Thr12Thr
M0061583 GJBIPAJG_00002 1452 3 Skin 0.19 protein_coding synonymous_variant LOW 6A>G Thr2Thr
M0061584 GJBIPAJG_00002 1473 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -16G>A None
M0061585 GJBIPAJG_00002 1490 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -33A>T None
M0061586 GJBIPAJG_00002 1518 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -61G>A None
M0061587 GJBIPAJG_00002 1520 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -63G>A None
M0061588 GJBIPAJG_00002 1543 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -86G>A None
M0061589 GJBIPAJG_00002 1584 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -127C>T None
M0061590 GJBIPAJG_00002 1599 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -142G>A None
M0061591 GJBIPAJG_00003 1677 3 Skin 0.19 protein_coding missense_variant MODERATE 758G>T Ser253Ile
M0061592 GJBIPAJG_00003 1685 3 Skin 0.19 protein_coding synonymous_variant LOW 750G>A Arg250Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term