Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2817
  Reference Plasmid   DP1806001482_bin.2__NODE_352_length_7097_cov_1.888682
  Reference Plasmid Size   7097
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0061955 EILBAKPE_00005 2531 7 Skin 0.39 protein_coding missense_variant MODERATE 127A>C Ile43Leu
M0061956 EILBAKPE_00005 2542 7 Skin 0.39 protein_coding synonymous_variant LOW 138T>A Ala46Ala
M0061957 EILBAKPE_00001 2750 14 Skin 0.78 protein_coding upstream_gene_variant MODIFIER -2360T>C None
M0061958 EILBAKPE_00006 3656 10 Skin 0.56 protein_coding synonymous_variant LOW 1308G>C Arg436Arg
M0061959 EILBAKPE_00004 1982 4 Skin 0.22 protein_coding synonymous_variant LOW 129A>G Glu43Glu
M0061960 EILBAKPE_00005 2446 4 Skin 0.22 protein_coding synonymous_variant LOW 42G>A Thr14Thr
M0061961 EILBAKPE_00006 4217 3 Skin 0.17 protein_coding missense_variant MODERATE 747T>A His249Gln
M0061962 EILBAKPE_00001 1807 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -1417G>T None
M0061963 EILBAKPE_00006 4447 9 Skin 0.50 protein_coding missense_variant MODERATE 517A>C Ile173Leu
M0061964 EILBAKPE_00006 4533 10 Skin 0.56 protein_coding missense_variant MODERATE 431T>C Val144Ala
M0061965 EILBAKPE_00006 4714 5 Skin 0.28 protein_coding missense_variant MODERATE 250G>A Ala84Thr
M0061966 EILBAKPE_00007 5090 9 Skin 0.50 protein_coding missense_variant MODERATE 313A>G Thr105Ala
M0061967 EILBAKPE_00002 5955 10 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -4917C>T None
M0061968 EILBAKPE_00003 6092 9 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4668T>C None
M0061969 EILBAKPE_00009 6229 4 Skin 0.22 protein_coding synonymous_variant LOW 615C>T Tyr205Tyr
M0061970 EILBAKPE_00005 2584 5 Skin 0.28 protein_coding synonymous_variant LOW 180A>C Ala60Ala
M0061971 EILBAKPE_00005 2614 5 Skin 0.28 protein_coding synonymous_variant LOW 210C>T Ala70Ala
M0061972 EILBAKPE_00007 5202 3 Skin 0.17 protein_coding synonymous_variant LOW 201G>A Thr67Thr
M0061973 EILBAKPE_00003 6063 5 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -4639G>A None
M0061974 EILBAKPE_00009 6126 5 Skin 0.28 protein_coding missense_variant MODERATE 718G>A Val240Ile
M0061975 EILBAKPE_00009 6202 10 Skin 0.56 protein_coding synonymous_variant LOW 642T>C Asp214Asp
M0061976 EILBAKPE_00009 6267 4 Skin 0.22 protein_coding missense_variant MODERATE 577G>A Ala193Thr
M0061977 EILBAKPE_00009 6802 3 Skin 0.17 protein_coding synonymous_variant LOW 42T>G Ala14Ala
M0061978 EILBAKPE_00006 6986 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -2023A>G None
M0061979 EILBAKPE_00003 6086 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4662C>T None
M0061980 EILBAKPE_00003 6090 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4666G>C None
M0061981 EILBAKPE_00003 6095 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4671A>G None
M0061982 EILBAKPE_00003 6097 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4673G>C None
M0061983 EILBAKPE_00003 6098 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4674C>T None
M0061984 EILBAKPE_00009 6154 3 Skin 0.17 protein_coding synonymous_variant LOW 690G>A Thr230Thr
M0061985 EILBAKPE_00009 6379 3 Skin 0.17 protein_coding synonymous_variant LOW 465G>A Lys155Lys
M0061986 EILBAKPE_00009 6497 4 Skin 0.22 protein_coding missense_variant MODERATE 347G>A Ser116Asn
M0061987 EILBAKPE_00009 6583 3 Skin 0.17 protein_coding synonymous_variant LOW 261G>A Gln87Gln
M0061988 EILBAKPE_00009 6751 3 Skin 0.17 protein_coding synonymous_variant LOW 93A>C Ser31Ser
M0061989 EILBAKPE_00004 2043 5 Skin 0.28 protein_coding missense_variant MODERATE 190G>A Val64Ile
M0061990 EILBAKPE_00004 2082 5 Skin 0.28 protein_coding synonymous_variant LOW 229C>A Arg77Arg
M0061991 EILBAKPE_00004 2099 6 Skin 0.33 protein_coding synonymous_variant LOW 246T>C His82His
M0061992 EILBAKPE_00004 2315 6 Skin 0.33 protein_coding synonymous_variant LOW 462C>T Gly154Gly
M0061993 EILBAKPE_00004 2321 3 Skin 0.17 protein_coding splice_region_variant&stop_retained_variant LOW 468G>A Ter156Ter
M0061994 EILBAKPE_00001 2352 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -1962T>C None
M0061995 EILBAKPE_00001 2353 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -1963C>T None
M0061996 EILBAKPE_00001 106 3 Skin 0.17 protein_coding missense_variant MODERATE 285A>C Gln95His
M0061997 EILBAKPE_00001 583 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -193A>G None
M0061998 EILBAKPE_00001 597 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -207T>C None
M0061999 EILBAKPE_00001 615 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -225G>A None
M0062000 EILBAKPE_00002 625 3 Skin 0.17 protein_coding synonymous_variant LOW 414A>G Glu138Glu
M0062001 EILBAKPE_00002 701 3 Skin 0.17 protein_coding missense_variant MODERATE 338G>A Gly113Asp
M0062002 EILBAKPE_00004 2255 3 Skin 0.17 protein_coding synonymous_variant LOW 402A>G Glu134Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term