Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2828
  Reference Plasmid   DP1807004337_bin.1__NODE_618_length_5118_cov_1.288304
  Reference Plasmid Size   5118
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0063730 EJDFMMNM_00002 785 6 Skin 0.86 protein_coding synonymous_variant LOW 1140T>C Thr380Thr
M0063731 EJDFMMNM_00002 830 6 Skin 0.86 protein_coding synonymous_variant LOW 1095A>G Lys365Lys
M0063732 EJDFMMNM_00002 887 3 Skin 0.43 protein_coding synonymous_variant LOW 1038A>T Ala346Ala
M0063733 EJDFMMNM_00002 896 3 Skin 0.43 protein_coding synonymous_variant LOW 1029C>T Gly343Gly
M0063734 EJDFMMNM_00002 917 3 Skin 0.43 protein_coding synonymous_variant LOW 1008C>T Val336Val
M0063735 EJDFMMNM_00002 1181 3 Skin 0.43 protein_coding synonymous_variant LOW 744C>T Asp248Asp
M0063736 EJDFMMNM_00002 1535 3 Skin 0.43 protein_coding synonymous_variant LOW 390G>A Ala130Ala
M0063737 EJDFMMNM_00002 1768 3 Skin 0.43 protein_coding missense_variant MODERATE 157G>C Ala53Pro
M0063738 EJDFMMNM_00003 2209 3 Skin 0.43 protein_coding missense_variant MODERATE 112C>G Gln38Glu
M0063739 EJDFMMNM_00003 2235 4 Skin 0.57 protein_coding synonymous_variant LOW 138G>A Ala46Ala
M0063740 EJDFMMNM_00003 2316 3 Skin 0.43 protein_coding synonymous_variant LOW 219T>A Ala73Ala
M0063741 EJDFMMNM_00003 2338 4 Skin 0.57 protein_coding missense_variant MODERATE 241A>C Ile81Leu
M0063742 EJDFMMNM_00003 2346 3 Skin 0.43 protein_coding synonymous_variant LOW 249C>G Pro83Pro
M0063743 EJDFMMNM_00003 2352 3 Skin 0.43 protein_coding synonymous_variant LOW 255A>G Glu85Glu
M0063744 EJDFMMNM_00003 2361 4 Skin 0.57 protein_coding synonymous_variant LOW 264T>C Asp88Asp
M0063745 EJDFMMNM_00002 2611 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -687A>G None
M0063746 EJDFMMNM_00002 2613 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -689G>A None
M0063747 EJDFMMNM_00002 2621 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -697G>A None
M0063748 EJDFMMNM_00002 2622 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -698G>A None
M0063749 EJDFMMNM_00002 2624 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -700A>T None
M0063750 EJDFMMNM_00002 2631 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -707C>T None
M0063751 EJDFMMNM_00002 2633 6 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -709G>T None
M0063752 EJDFMMNM_00004 2860 4 Skin 0.57 protein_coding missense_variant MODERATE 17G>A Arg6His
M0063753 EJDFMMNM_00004 2903 4 Skin 0.57 protein_coding synonymous_variant LOW 60A>G Gly20Gly
M0063754 EJDFMMNM_00004 2942 7 Skin 1.00 protein_coding synonymous_variant LOW 99T>C Val33Val
M0063755 EJDFMMNM_00004 2958 7 Skin 1.00 protein_coding missense_variant MODERATE 115C>A Leu39Ile
M0063756 EJDFMMNM_00004 2976 6 Skin 0.86 protein_coding missense_variant MODERATE 133A>G Thr45Ala
M0063757 EJDFMMNM_00004 2984 6 Skin 0.86 protein_coding synonymous_variant LOW 141T>C Arg47Arg
M0063758 EJDFMMNM_00004 2991 5 Skin 0.71 protein_coding synonymous_variant LOW 148C>T Leu50Leu
M0063759 EJDFMMNM_00004 3042 6 Skin 0.86 protein_coding missense_variant MODERATE 199G>T Ala67Ser
M0063760 EJDFMMNM_00004 3056 7 Skin 1.00 protein_coding synonymous_variant LOW 213G>A Gly71Gly
M0063761 EJDFMMNM_00004 3062 7 Skin 1.00 protein_coding synonymous_variant LOW 219A>G Pro73Pro
M0063762 EJDFMMNM_00004 3176 7 Skin 1.00 protein_coding synonymous_variant LOW 333C>T Ser111Ser
M0063763 EJDFMMNM_00004 3189 7 Skin 1.00 protein_coding synonymous_variant LOW 346T>C Leu116Leu
M0063764 EJDFMMNM_00004 3212 7 Skin 1.00 protein_coding synonymous_variant LOW 369T>C Gly123Gly
M0063765 EJDFMMNM_00004 3318 7 Skin 1.00 protein_coding missense_variant MODERATE 475T>G Cys159Gly
M0063766 EJDFMMNM_00004 3396 5 Skin 0.71 protein_coding synonymous_variant LOW 553T>C Leu185Leu
M0063767 EJDFMMNM_00004 3583 4 Skin 0.57 protein_coding missense_variant MODERATE 740T>C Ile247Thr
M0063768 EJDFMMNM_00004 3614 3 Skin 0.43 protein_coding synonymous_variant LOW 771T>C Gly257Gly
M0063769 EJDFMMNM_00004 3617 4 Skin 0.57 protein_coding synonymous_variant LOW 774C>T Gly258Gly
M0063770 EJDFMMNM_00004 3668 3 Skin 0.43 protein_coding synonymous_variant LOW 825A>G Thr275Thr
M0063771 EJDFMMNM_00004 3695 4 Skin 0.57 protein_coding synonymous_variant LOW 852T>C Ala284Ala
M0063772 EJDFMMNM_00004 3785 6 Skin 0.86 protein_coding synonymous_variant LOW 942C>T His314His
M0063773 EJDFMMNM_00004 3803 7 Skin 1.00 protein_coding synonymous_variant LOW 960T>C Val320Val
M0063774 EJDFMMNM_00004 3806 6 Skin 0.86 protein_coding synonymous_variant LOW 963A>C Ile321Ile
M0063775 EJDFMMNM_00004 3818 3 Skin 0.43 protein_coding synonymous_variant LOW 975C>T Ser325Ser
M0063776 EJDFMMNM_00004 4280 4 Skin 0.57 protein_coding synonymous_variant LOW 1437T>C Thr479Thr
M0063777 EJDFMMNM_00004 4286 3 Skin 0.43 protein_coding synonymous_variant LOW 1443A>C Ser481Ser
M0063778 EJDFMMNM_00004 4310 4 Skin 0.57 protein_coding synonymous_variant LOW 1467T>C Thr489Thr
M0063779 EJDFMMNM_00001 122 4 Skin 0.57 protein_coding missense_variant MODERATE 82C>A Pro28Thr
M0063780 EJDFMMNM_00001 205 3 Skin 0.43 protein_coding synonymous_variant LOW 165T>G Arg55Arg
M0063781 EJDFMMNM_00001 214 4 Skin 0.57 protein_coding synonymous_variant LOW 174T>C Asp58Asp
M0063782 EJDFMMNM_00001 215 4 Skin 0.57 protein_coding missense_variant MODERATE 175C>T Leu59Phe
M0063783 EJDFMMNM_00002 968 3 Skin 0.43 protein_coding synonymous_variant LOW 957T>G Arg319Arg
M0063784 EJDFMMNM_00002 1829 3 Skin 0.43 protein_coding synonymous_variant LOW 96C>T Cys32Cys
M0063785 EJDFMMNM_00002 1830 3 Skin 0.43 protein_coding missense_variant MODERATE 95G>T Cys32Phe
M0063786 EJDFMMNM_00002 1831 3 Skin 0.43 protein_coding missense_variant MODERATE 94T>C Cys32Arg
M0063787 EJDFMMNM_00002 1841 3 Skin 0.43 protein_coding synonymous_variant LOW 84G>A Ala28Ala
M0063788 EJDFMMNM_00002 1847 3 Skin 0.43 protein_coding synonymous_variant LOW 78C>T Gly26Gly
M0063789 EJDFMMNM_00003 2379 3 Skin 0.43 protein_coding synonymous_variant LOW 282C>T Gly94Gly
M0063790 EJDFMMNM_00004 3926 4 Skin 0.57 protein_coding synonymous_variant LOW 1083G>A Thr361Thr
M0063791 EJDFMMNM_00004 4072 4 Skin 0.57 protein_coding missense_variant MODERATE 1229T>C Ile410Thr
M0063792 EJDFMMNM_00004 4075 4 Skin 0.57 protein_coding missense_variant MODERATE 1232A>G Asp411Gly
M0063793 EJDFMMNM_00004 4076 4 Skin 0.57 protein_coding missense_variant MODERATE 1233C>G Asp411Glu
M0063794 EJDFMMNM_00004 4094 4 Skin 0.57 protein_coding synonymous_variant LOW 1251G>A Gly417Gly
M0063795 EJDFMMNM_00004 4196 3 Skin 0.43 protein_coding synonymous_variant LOW 1353T>C Thr451Thr
M0063796 EJDFMMNM_00004 4460 3 Skin 0.43 protein_coding synonymous_variant LOW 1617T>A Ala539Ala
M0063797 EJDFMMNM_00005 4576 3 Skin 0.43 protein_coding synonymous_variant LOW 87C>T Ser29Ser
M0063798 EJDFMMNM_00005 4578 3 Skin 0.43 protein_coding missense_variant MODERATE 89T>C Val30Ala
M0063799 EJDFMMNM_00005 4624 4 Skin 0.57 protein_coding stop_gained HIGH 135C>A Tyr45*
M0063800 EJDFMMNM_00002 4827 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -2903T>C None
M0063801 EJDFMMNM_00002 881 3 Skin 0.43 protein_coding synonymous_variant LOW 1044C>T Val348Val
M0063802 EJDFMMNM_00004 3455 3 Skin 0.43 protein_coding synonymous_variant LOW 612G>A Ala204Ala
M0063803 EJDFMMNM_00004 3906 3 Skin 0.43 protein_coding missense_variant MODERATE 1063G>A Ala355Thr
M0063804 EJDFMMNM_00004 3908 3 Skin 0.43 protein_coding synonymous_variant LOW 1065C>T Ala355Ala
M0063805 EJDFMMNM_00004 3911 3 Skin 0.43 protein_coding synonymous_variant LOW 1068T>C His356His
M0063806 EJDFMMNM_00004 3935 3 Skin 0.43 protein_coding synonymous_variant LOW 1092C>T Tyr364Tyr
M0063807 EJDFMMNM_00004 3953 3 Skin 0.43 protein_coding synonymous_variant LOW 1110G>A Val370Val
M0063808 EJDFMMNM_00004 3987 4 Skin 0.57 protein_coding synonymous_variant LOW 1144C>T Leu382Leu
M0063809 EJDFMMNM_00004 4061 3 Skin 0.43 protein_coding synonymous_variant LOW 1218T>C Asp406Asp
M0063810 EJDFMMNM_00004 4071 3 Skin 0.43 protein_coding missense_variant MODERATE 1228A>G Ile410Val
M0063811 EJDFMMNM_00004 3707 3 Skin 0.43 protein_coding synonymous_variant LOW 864T>C Asp288Asp
M0063812 EJDFMMNM_00004 3716 3 Skin 0.43 protein_coding synonymous_variant LOW 873G>A Ala291Ala
M0063813 EJDFMMNM_00004 3728 3 Skin 0.43 protein_coding synonymous_variant LOW 885G>T Pro295Pro
M0063814 EJDFMMNM_00004 3734 3 Skin 0.43 protein_coding synonymous_variant LOW 891A>C Thr297Thr
M0063815 EJDFMMNM_00004 3752 3 Skin 0.43 protein_coding synonymous_variant LOW 909G>A Pro303Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term