Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2853
  Reference Plasmid   DP1807004434_bin.11__NODE_565_length_5558_cov_0.870672
  Reference Plasmid Size   5558
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0064355 KAIFPFKH_00006 3917 3 Skin 0.30 protein_coding synonymous_variant LOW 1140T>C Pro380Pro
M0064356 KAIFPFKH_00006 4045 3 Skin 0.30 protein_coding missense_variant MODERATE 1012G>A Ala338Thr
M0064357 KAIFPFKH_00006 4127 3 Skin 0.30 protein_coding synonymous_variant LOW 930T>C Asn310Asn
M0064358 KAIFPFKH_00006 4132 3 Skin 0.30 protein_coding missense_variant MODERATE 925A>C Lys309Gln
M0064359 KAIFPFKH_00006 4141 3 Skin 0.30 protein_coding missense_variant MODERATE 916A>G Thr306Ala
M0064360 KAIFPFKH_00006 4193 3 Skin 0.30 protein_coding synonymous_variant LOW 864G>C Ala288Ala
M0064361 KAIFPFKH_00006 4223 3 Skin 0.30 protein_coding synonymous_variant LOW 834C>T Gly278Gly
M0064362 KAIFPFKH_00006 4235 3 Skin 0.30 protein_coding missense_variant MODERATE 822G>C Glu274Asp
M0064363 KAIFPFKH_00006 4238 3 Skin 0.30 protein_coding synonymous_variant LOW 819T>C Pro273Pro
M0064364 KAIFPFKH_00006 4248 3 Skin 0.30 protein_coding missense_variant MODERATE 809C>A Ala270Glu
M0064365 KAIFPFKH_00006 4250 3 Skin 0.30 protein_coding synonymous_variant LOW 807G>C Ala269Ala
M0064366 KAIFPFKH_00006 4259 3 Skin 0.30 protein_coding synonymous_variant LOW 798A>G Glu266Glu
M0064367 KAIFPFKH_00006 4280 3 Skin 0.30 protein_coding synonymous_variant LOW 777T>C Ala259Ala
M0064368 KAIFPFKH_00006 4298 3 Skin 0.30 protein_coding synonymous_variant LOW 759A>G Gln253Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term