Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2857
  Reference Plasmid   DP1807004435_bin.21__NODE_2021_length_3603_cov_1.353881
  Reference Plasmid Size   3603
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0064381 LLFPLNBI_00002 1142 5 Skin 0.56 protein_coding synonymous_variant LOW 205T>C Leu69Leu
M0064382 LLFPLNBI_00002 1161 5 Skin 0.56 protein_coding synonymous_variant LOW 186T>C Gly62Gly
M0064383 LLFPLNBI_00002 1203 5 Skin 0.56 protein_coding synonymous_variant LOW 144A>G Ala48Ala
M0064384 LLFPLNBI_00002 1228 5 Skin 0.56 protein_coding missense_variant MODERATE 119A>G Glu40Gly
M0064385 LLFPLNBI_00003 1640 4 Skin 0.44 protein_coding synonymous_variant LOW 289T>C Leu97Leu
M0064386 LLFPLNBI_00004 2639 7 Skin 0.78 protein_coding synonymous_variant LOW 123C>T Val41Val
M0064387 LLFPLNBI_00004 2640 7 Skin 0.78 protein_coding missense_variant MODERATE 122T>C Val41Ala
M0064388 LLFPLNBI_00004 2642 7 Skin 0.78 protein_coding synonymous_variant LOW 120T>G Pro40Pro
M0064389 LLFPLNBI_00004 2645 7 Skin 0.78 protein_coding synonymous_variant LOW 117T>C Ala39Ala
M0064390 LLFPLNBI_00004 2652 7 Skin 0.78 protein_coding missense_variant MODERATE 110C>A Ser37Tyr
M0064391 LLFPLNBI_00002 972 3 Skin 0.33 protein_coding synonymous_variant LOW 375C>G Leu125Leu
M0064392 LLFPLNBI_00002 978 3 Skin 0.33 protein_coding synonymous_variant LOW 369C>G Leu123Leu
M0064393 LLFPLNBI_00002 981 3 Skin 0.33 protein_coding synonymous_variant LOW 366A>G Ala122Ala
M0064394 LLFPLNBI_00002 1002 3 Skin 0.33 protein_coding missense_variant MODERATE 345C>G Ser115Arg
M0064395 LLFPLNBI_00002 1004 3 Skin 0.33 protein_coding missense_variant MODERATE 343A>G Ser115Gly
M0064396 LLFPLNBI_00002 1011 3 Skin 0.33 protein_coding synonymous_variant LOW 336C>G Ala112Ala
M0064397 LLFPLNBI_00002 1020 3 Skin 0.33 protein_coding synonymous_variant LOW 327T>C Tyr109Tyr
M0064398 LLFPLNBI_00002 1029 3 Skin 0.33 protein_coding synonymous_variant LOW 318C>T Ile106Ile
M0064399 LLFPLNBI_00002 1053 3 Skin 0.33 protein_coding synonymous_variant LOW 294C>G Gly98Gly
M0064400 LLFPLNBI_00002 1058 3 Skin 0.33 protein_coding missense_variant MODERATE 289G>A Gly97Ser
M0064401 LLFPLNBI_00002 1064 3 Skin 0.33 protein_coding missense_variant MODERATE 283A>G Ser95Gly
M0064402 LLFPLNBI_00002 1067 3 Skin 0.33 protein_coding missense_variant MODERATE 280G>A Glu94Lys
M0064403 LLFPLNBI_00002 1122 3 Skin 0.33 protein_coding synonymous_variant LOW 225T>C Asp75Asp
M0064404 LLFPLNBI_00001 1351 6 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -599G>A None
M0064405 LLFPLNBI_00001 1353 6 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -601A>G None
M0064406 LLFPLNBI_00001 1357 6 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -605G>C None
M0064407 LLFPLNBI_00003 1668 3 Skin 0.33 protein_coding synonymous_variant LOW 261G>C Pro87Pro
M0064408 LLFPLNBI_00004 2411 3 Skin 0.33 protein_coding synonymous_variant LOW 351G>A Lys117Lys
M0064409 LLFPLNBI_00005 2964 3 Skin 0.33 protein_coding missense_variant MODERATE 631G>A Gly211Arg
M0064410 LLFPLNBI_00005 2973 3 Skin 0.33 protein_coding missense_variant MODERATE 622C>T Leu208Phe
M0064411 LLFPLNBI_00005 2978 3 Skin 0.33 protein_coding missense_variant MODERATE 617C>T Pro206Leu
M0064412 LLFPLNBI_00005 2988 3 Skin 0.33 protein_coding missense_variant MODERATE 607G>A Ala203Thr
M0064413 LLFPLNBI_00005 3072 3 Skin 0.33 protein_coding missense_variant MODERATE 523A>C Ser175Arg
M0064414 LLFPLNBI_00005 3084 3 Skin 0.33 protein_coding missense_variant MODERATE 511A>G Thr171Ala
M0064415 LLFPLNBI_00005 3426 4 Skin 0.44 protein_coding missense_variant MODERATE 169A>G Asn57Asp
M0064416 LLFPLNBI_00005 3456 5 Skin 0.56 protein_coding missense_variant MODERATE 139C>G His47Asp
M0064417 LLFPLNBI_00005 3459 5 Skin 0.56 protein_coding missense_variant MODERATE 136T>C Phe46Leu
M0064418 LLFPLNBI_00005 3468 3 Skin 0.33 protein_coding missense_variant MODERATE 127G>A Gly43Arg
M0064419 LLFPLNBI_00004 2587 3 Skin 0.33 protein_coding synonymous_variant LOW 175T>C Leu59Leu
M0064420 LLFPLNBI_00005 3435 3 Skin 0.33 protein_coding missense_variant MODERATE 160A>G Asn54Asp
M0064421 LLFPLNBI_00005 2933 3 Skin 0.33 protein_coding missense_variant MODERATE 662C>G Thr221Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term