Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2878
  Reference Plasmid   DP1808006645_bin.7__NODE_1138_length_3386_cov_0.612717
  Reference Plasmid Size   3386
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0065077 GIOMFHJH_00002 1088 5 Skin 1.00 protein_coding synonymous_variant LOW 1377C>G Ala459Ala
M0065078 GIOMFHJH_00002 1208 4 Skin 0.80 protein_coding synonymous_variant LOW 1257T>C Ile419Ile
M0065079 GIOMFHJH_00002 1212 4 Skin 0.80 protein_coding missense_variant MODERATE 1253G>C Ser418Thr
M0065080 GIOMFHJH_00002 1213 4 Skin 0.80 protein_coding missense_variant MODERATE 1252A>T Ser418Cys
M0065081 GIOMFHJH_00002 1214 3 Skin 0.60 protein_coding synonymous_variant LOW 1251C>T Ile417Ile
M0065082 GIOMFHJH_00002 1217 4 Skin 0.80 protein_coding synonymous_variant LOW 1248A>C Arg416Arg
M0065083 GIOMFHJH_00002 1535 4 Skin 0.80 protein_coding synonymous_variant LOW 930T>C Leu310Leu
M0065084 GIOMFHJH_00002 1713 3 Skin 0.60 protein_coding missense_variant MODERATE 752G>A Arg251Lys
M0065085 GIOMFHJH_00002 2222 4 Skin 0.80 protein_coding synonymous_variant LOW 243T>C Ser81Ser
M0065086 GIOMFHJH_00002 2485 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -21T>C None
M0065087 GIOMFHJH_00003 2940 3 Skin 0.60 protein_coding synonymous_variant LOW 327T>C Ile109Ile
M0065088 GIOMFHJH_00002 3086 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -622A>C None
M0065089 GIOMFHJH_00004 3128 3 Skin 0.60 protein_coding missense_variant MODERATE 247A>C Thr83Pro
M0065090 GIOMFHJH_00004 3322 3 Skin 0.60 protein_coding missense_variant MODERATE 53G>T Arg18Leu
M0065091 GIOMFHJH_00002 1085 4 Skin 0.80 protein_coding synonymous_variant LOW 1380A>G Pro460Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term