Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2879
  Reference Plasmid   DP1808006645_bin.7__NODE_249_length_6190_cov_0.255131
  Reference Plasmid Size   6190
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0065092 FABJBHNB_00001 65 4 Skin 0.44 protein_coding downstream_gene_variant MODIFIER *69T>G None
M0065093 FABJBHNB_00001 66 4 Skin 0.44 protein_coding downstream_gene_variant MODIFIER *68C>T None
M0065094 FABJBHNB_00001 68 4 Skin 0.44 protein_coding downstream_gene_variant MODIFIER *66G>A None
M0065095 FABJBHNB_00001 89 4 Skin 0.44 protein_coding downstream_gene_variant MODIFIER *45T>G None
M0065096 FABJBHNB_00001 179 5 Skin 0.56 protein_coding synonymous_variant LOW 549C>T Ser183Ser
M0065097 FABJBHNB_00001 191 4 Skin 0.44 protein_coding synonymous_variant LOW 537A>G Glu179Glu
M0065098 FABJBHNB_00001 194 4 Skin 0.44 protein_coding synonymous_variant LOW 534C>A Gly178Gly
M0065099 FABJBHNB_00001 197 6 Skin 0.67 protein_coding synonymous_variant LOW 531G>A Glu177Glu
M0065100 FABJBHNB_00001 398 5 Skin 0.56 protein_coding synonymous_variant LOW 330C>T Arg110Arg
M0065101 FABJBHNB_00001 410 5 Skin 0.56 protein_coding synonymous_variant LOW 318C>T Ala106Ala
M0065102 FABJBHNB_00001 440 5 Skin 0.56 protein_coding synonymous_variant LOW 288G>A Leu96Leu
M0065103 FABJBHNB_00001 458 7 Skin 0.78 protein_coding synonymous_variant LOW 270G>A Glu90Glu
M0065104 FABJBHNB_00001 467 6 Skin 0.67 protein_coding synonymous_variant LOW 261C>G Pro87Pro
M0065105 FABJBHNB_00001 470 6 Skin 0.67 protein_coding synonymous_variant LOW 258C>T Tyr86Tyr
M0065106 FABJBHNB_00001 629 4 Skin 0.44 protein_coding synonymous_variant LOW 99G>A Lys33Lys
M0065107 FABJBHNB_00001 662 4 Skin 0.44 protein_coding synonymous_variant LOW 66C>G Gly22Gly
M0065108 FABJBHNB_00001 665 4 Skin 0.44 protein_coding synonymous_variant LOW 63C>T Ser21Ser
M0065109 FABJBHNB_00001 694 4 Skin 0.44 protein_coding synonymous_variant LOW 34T>C Leu12Leu
M0065110 FABJBHNB_00001 695 4 Skin 0.44 protein_coding synonymous_variant LOW 33C>A Arg11Arg
M0065111 FABJBHNB_00001 705 6 Skin 0.67 protein_coding missense_variant MODERATE 23G>C Gly8Ala
M0065112 FABJBHNB_00001 714 4 Skin 0.44 protein_coding missense_variant MODERATE 14C>T Pro5Leu
M0065113 FABJBHNB_00001 718 6 Skin 0.67 protein_coding missense_variant MODERATE 10G>A Ala4Thr
M0065114 FABJBHNB_00001 721 6 Skin 0.67 protein_coding missense_variant MODERATE 7A>G Ser3Gly
M0065115 FABJBHNB_00002 741 6 Skin 0.67 protein_coding missense_variant MODERATE 1018T>C Tyr340His
M0065116 FABJBHNB_00002 913 9 Skin 1.00 protein_coding synonymous_variant LOW 846A>G Gly282Gly
M0065117 FABJBHNB_00002 1408 6 Skin 0.67 protein_coding synonymous_variant LOW 351C>G Thr117Thr
M0065118 FABJBHNB_00002 1422 5 Skin 0.56 protein_coding missense_variant MODERATE 337G>A Ala113Thr
M0065119 FABJBHNB_00002 1423 4 Skin 0.44 protein_coding synonymous_variant LOW 336C>G Ser112Ser
M0065120 FABJBHNB_00002 1425 5 Skin 0.56 protein_coding missense_variant MODERATE 334T>C Ser112Pro
M0065121 FABJBHNB_00002 1429 4 Skin 0.44 protein_coding synonymous_variant LOW 330C>T Asp110Asp
M0065122 FABJBHNB_00002 1436 5 Skin 0.56 protein_coding missense_variant MODERATE 323T>G Leu108Arg
M0065123 FABJBHNB_00002 1441 5 Skin 0.56 protein_coding synonymous_variant LOW 318G>T Val106Val
M0065124 FABJBHNB_00002 1443 5 Skin 0.56 protein_coding missense_variant MODERATE 316G>A Val106Met
M0065125 FABJBHNB_00002 1444 5 Skin 0.56 protein_coding synonymous_variant LOW 315C>G Leu105Leu
M0065126 FABJBHNB_00002 1447 5 Skin 0.56 protein_coding synonymous_variant LOW 312A>G Val104Val
M0065127 FABJBHNB_00003 2075 8 Skin 0.89 protein_coding missense_variant MODERATE 103G>A Val35Met
M0065128 FABJBHNB_00005 3563 3 Skin 0.33 protein_coding synonymous_variant LOW 399C>G Arg133Arg
M0065129 FABJBHNB_00005 3632 5 Skin 0.56 protein_coding synonymous_variant LOW 330C>T Ala110Ala
M0065130 FABJBHNB_00001 3984 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3257T>G None
M0065131 FABJBHNB_00001 3987 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3260A>G None
M0065132 FABJBHNB_00001 3990 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3263T>C None
M0065133 FABJBHNB_00006 4302 5 Skin 0.56 protein_coding missense_variant MODERATE 41T>C Val14Ala
M0065134 FABJBHNB_00007 4357 3 Skin 0.33 protein_coding synonymous_variant LOW 363A>G Arg121Arg
M0065135 FABJBHNB_00007 4362 3 Skin 0.33 protein_coding synonymous_variant LOW 358T>C Leu120Leu
M0065136 FABJBHNB_00007 4369 3 Skin 0.33 protein_coding missense_variant MODERATE 351G>C Gln117His
M0065137 FABJBHNB_00007 4386 3 Skin 0.33 protein_coding missense_variant MODERATE 334A>G Thr112Ala
M0065138 FABJBHNB_00007 4387 3 Skin 0.33 protein_coding synonymous_variant LOW 333C>T Asn111Asn
M0065139 FABJBHNB_00007 4388 3 Skin 0.33 protein_coding missense_variant MODERATE 332A>G Asn111Ser
M0065140 FABJBHNB_00007 4394 3 Skin 0.33 protein_coding missense_variant MODERATE 326C>A Thr109Lys
M0065141 FABJBHNB_00007 4400 3 Skin 0.33 protein_coding missense_variant MODERATE 320G>C Gly107Ala
M0065142 FABJBHNB_00007 4540 5 Skin 0.56 protein_coding synonymous_variant LOW 180C>G Val60Val
M0065143 FABJBHNB_00001 4835 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -4108T>G None
M0065144 FABJBHNB_00001 152 4 Skin 0.44 protein_coding synonymous_variant LOW 576G>A Gln192Gln
M0065145 FABJBHNB_00001 242 4 Skin 0.44 protein_coding synonymous_variant LOW 486A>G Glu162Glu
M0065146 FABJBHNB_00001 296 5 Skin 0.56 protein_coding synonymous_variant LOW 432A>G Glu144Glu
M0065147 FABJBHNB_00001 461 3 Skin 0.33 protein_coding synonymous_variant LOW 267T>C Ser89Ser
M0065148 FABJBHNB_00001 538 3 Skin 0.33 protein_coding missense_variant MODERATE 190T>C Ser64Pro
M0065149 FABJBHNB_00002 907 3 Skin 0.33 protein_coding synonymous_variant LOW 852G>A Glu284Glu
M0065150 FABJBHNB_00002 1099 3 Skin 0.33 protein_coding synonymous_variant LOW 660A>G Glu220Glu
M0065151 FABJBHNB_00002 1105 3 Skin 0.33 protein_coding synonymous_variant LOW 654C>T Tyr218Tyr
M0065152 FABJBHNB_00002 1336 3 Skin 0.33 protein_coding synonymous_variant LOW 423G>C Val141Val
M0065153 FABJBHNB_00004 2222 7 Skin 0.78 protein_coding synonymous_variant LOW 441G>A Glu147Glu
M0065154 FABJBHNB_00004 2234 7 Skin 0.78 protein_coding synonymous_variant LOW 429C>T Tyr143Tyr
M0065155 FABJBHNB_00005 3386 5 Skin 0.56 protein_coding synonymous_variant LOW 576T>C Val192Val
M0065156 FABJBHNB_00005 3942 3 Skin 0.33 protein_coding missense_variant MODERATE 20G>C Gly7Ala
M0065157 FABJBHNB_00004 2593 4 Skin 0.44 protein_coding missense_variant MODERATE 70A>G Lys24Glu
M0065158 FABJBHNB_00005 2869 4 Skin 0.44 protein_coding missense_variant MODERATE 1093C>T Pro365Ser
M0065159 FABJBHNB_00005 2726 3 Skin 0.33 protein_coding missense_variant MODERATE 1236C>G Ile412Met
M0065160 FABJBHNB_00005 3418 4 Skin 0.44 protein_coding missense_variant MODERATE 544C>A His182Asn
M0065161 FABJBHNB_00005 3425 4 Skin 0.44 protein_coding synonymous_variant LOW 537A>G Ala179Ala
M0065162 FABJBHNB_00005 3428 4 Skin 0.44 protein_coding synonymous_variant LOW 534C>T Ala178Ala
M0065163 FABJBHNB_00005 3473 4 Skin 0.44 protein_coding synonymous_variant LOW 489T>C Gly163Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term