Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2880
  Reference Plasmid   DP1808006645_bin.7__NODE_520_length_4800_cov_2.889173
  Reference Plasmid Size   4800
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0065164 GKLHCBAC_00001 410 3 Skin 0.75 protein_coding missense_variant MODERATE 406A>T Ser136Cys
M0065165 GKLHCBAC_00001 411 3 Skin 0.75 protein_coding missense_variant MODERATE 407G>C Ser136Thr
M0065166 GKLHCBAC_00001 412 3 Skin 0.75 protein_coding synonymous_variant LOW 408T>C Ser136Ser
M0065167 GKLHCBAC_00001 415 3 Skin 0.75 protein_coding synonymous_variant LOW 411T>C Asp137Asp
M0065168 GKLHCBAC_00001 472 3 Skin 0.75 protein_coding synonymous_variant LOW 468G>A Ala156Ala
M0065169 GKLHCBAC_00001 475 3 Skin 0.75 protein_coding synonymous_variant LOW 471C>G Thr157Thr
M0065170 GKLHCBAC_00001 502 3 Skin 0.75 protein_coding synonymous_variant LOW 498C>T Asp166Asp
M0065171 GKLHCBAC_00001 505 3 Skin 0.75 protein_coding synonymous_variant LOW 501T>C Phe167Phe
M0065172 GKLHCBAC_00001 523 3 Skin 0.75 protein_coding synonymous_variant LOW 519G>C Leu173Leu
M0065173 GKLHCBAC_00001 604 3 Skin 0.75 protein_coding synonymous_variant LOW 600A>C Ala200Ala
M0065174 GKLHCBAC_00001 787 3 Skin 0.75 protein_coding synonymous_variant LOW 783G>C Thr261Thr
M0065175 GKLHCBAC_00001 790 3 Skin 0.75 protein_coding synonymous_variant LOW 786C>T His262His
M0065176 GKLHCBAC_00001 794 3 Skin 0.75 protein_coding missense_variant MODERATE 790T>C Cys264Arg
M0065177 GKLHCBAC_00001 1024 3 Skin 0.75 protein_coding synonymous_variant LOW 1020A>G Glu340Glu
M0065178 GKLHCBAC_00001 1025 3 Skin 0.75 protein_coding missense_variant MODERATE 1021G>C Asp341His
M0065179 GKLHCBAC_00001 1027 3 Skin 0.75 protein_coding missense_variant MODERATE 1023C>G Asp341Glu
M0065180 GKLHCBAC_00001 1135 4 Skin 1.00 protein_coding synonymous_variant LOW 1131T>C Ala377Ala
M0065181 GKLHCBAC_00001 1183 3 Skin 0.75 protein_coding synonymous_variant LOW 1179T>A Ile393Ile
M0065182 GKLHCBAC_00002 1501 3 Skin 0.75 protein_coding synonymous_variant LOW 42G>T Arg14Arg
M0065183 GKLHCBAC_00001 637 3 Skin 0.75 protein_coding synonymous_variant LOW 633G>A Leu211Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term