Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2881
  Reference Plasmid   DP1808006646_bin.3_new__NODE_3341_length_2108_cov_0.417123
  Reference Plasmid Size   2108
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0065184 FKDACMBL_00001 103 12 Skin 0.67 protein_coding missense_variant MODERATE 70A>G Asn24Asp
M0065185 FKDACMBL_00001 181 12 Skin 0.67 protein_coding missense_variant MODERATE 148T>A Tyr50Asn
M0065186 FKDACMBL_00002 265 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -228T>C None
M0065187 FKDACMBL_00002 273 11 Skin 0.61 protein_coding upstream_gene_variant MODIFIER -220G>C None
M0065188 FKDACMBL_00003 1225 3 Skin 0.17 protein_coding synonymous_variant LOW 291G>A Gln97Gln
M0065189 FKDACMBL_00003 1226 4 Skin 0.22 protein_coding missense_variant MODERATE 292G>A Val98Ile
M0065190 FKDACMBL_00003 1232 4 Skin 0.22 protein_coding synonymous_variant LOW 298C>T Leu100Leu
M0065191 FKDACMBL_00003 1624 4 Skin 0.22 protein_coding synonymous_variant LOW 690T>C Ser230Ser
M0065192 FKDACMBL_00003 1741 3 Skin 0.17 protein_coding synonymous_variant LOW 807T>A Ser269Ser
M0065193 FKDACMBL_00001 2073 3 Skin 0.17 protein_coding downstream_gene_variant MODIFIER *1818G>A None
M0065194 FKDACMBL_00002 257 8 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -236G>A None
M0065195 FKDACMBL_00002 272 8 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -221G>C None
M0065196 FKDACMBL_00002 278 8 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -215G>T None
M0065197 FKDACMBL_00002 279 8 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -214C>T None
M0065198 FKDACMBL_00002 310 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -183G>A None
M0065199 FKDACMBL_00002 333 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -160G>A None
M0065200 FKDACMBL_00002 335 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -158C>T None
M0065201 FKDACMBL_00002 410 11 Skin 0.61 protein_coding upstream_gene_variant MODIFIER -83C>T None
M0065202 FKDACMBL_00002 538 9 Skin 0.50 protein_coding missense_variant MODERATE 46A>C Lys16Gln
M0065203 FKDACMBL_00002 549 9 Skin 0.50 protein_coding synonymous_variant LOW 57C>A Ala19Ala
M0065204 FKDACMBL_00002 572 3 Skin 0.17 protein_coding missense_variant MODERATE 80A>G Lys27Arg
M0065205 FKDACMBL_00001 162 3 Skin 0.17 protein_coding synonymous_variant LOW 129G>A Gln43Gln
M0065206 FKDACMBL_00002 300 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -193G>A None
M0065207 FKDACMBL_00003 1147 3 Skin 0.17 protein_coding synonymous_variant LOW 213A>C Gly71Gly
M0065208 FKDACMBL_00002 401 6 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -92T>C None
M0065209 FKDACMBL_00002 457 7 Skin 0.39 protein_coding upstream_gene_variant MODIFIER -36A>T None
M0065210 FKDACMBL_00002 529 3 Skin 0.17 protein_coding missense_variant MODERATE 37A>G Ile13Val
M0065211 FKDACMBL_00002 900 8 Skin 0.44 protein_coding synonymous_variant LOW 408A>G Leu136Leu
M0065212 FKDACMBL_00001 230 5 Skin 0.28 protein_coding missense_variant MODERATE 197G>A Arg66Gln
M0065213 FKDACMBL_00001 233 5 Skin 0.28 protein_coding missense_variant MODERATE 200A>G Asn67Ser
M0065214 FKDACMBL_00002 846 5 Skin 0.28 protein_coding synonymous_variant LOW 354T>C Asn118Asn
M0065215 FKDACMBL_00002 640 4 Skin 0.22 protein_coding missense_variant MODERATE 148G>A Val50Ile
M0065216 FKDACMBL_00002 714 5 Skin 0.28 protein_coding synonymous_variant LOW 222A>T Ile74Ile
M0065217 FKDACMBL_00002 730 4 Skin 0.22 protein_coding missense_variant MODERATE 238C>A Leu80Met
M0065218 FKDACMBL_00002 744 4 Skin 0.22 protein_coding synonymous_variant LOW 252A>G Glu84Glu
M0065219 FKDACMBL_00002 768 4 Skin 0.22 protein_coding synonymous_variant LOW 276T>C Phe92Phe
M0065220 FKDACMBL_00002 769 4 Skin 0.22 protein_coding missense_variant MODERATE 277C>A Gln93Lys
M0065221 FKDACMBL_00002 771 4 Skin 0.22 protein_coding synonymous_variant LOW 279A>G Gln93Gln
M0065222 FKDACMBL_00002 774 4 Skin 0.22 protein_coding synonymous_variant LOW 282C>A Thr94Thr
M0065223 FKDACMBL_00002 779 4 Skin 0.22 protein_coding missense_variant MODERATE 287C>A Ala96Glu
M0065224 FKDACMBL_00002 780 4 Skin 0.22 protein_coding synonymous_variant LOW 288G>A Ala96Ala
M0065225 FKDACMBL_00002 786 4 Skin 0.22 protein_coding synonymous_variant LOW 294G>A Leu98Leu
M0065226 FKDACMBL_00002 807 4 Skin 0.22 protein_coding synonymous_variant LOW 315T>C Phe105Phe
M0065227 FKDACMBL_00002 813 4 Skin 0.22 protein_coding synonymous_variant LOW 321G>A Arg107Arg
M0065228 FKDACMBL_00002 816 4 Skin 0.22 protein_coding synonymous_variant LOW 324A>T Ile108Ile
M0065229 FKDACMBL_00002 822 4 Skin 0.22 protein_coding synonymous_variant LOW 330T>C Asn110Asn
M0065230 FKDACMBL_00002 829 4 Skin 0.22 protein_coding synonymous_variant LOW 337C>A Arg113Arg
M0065231 FKDACMBL_00002 835 4 Skin 0.22 protein_coding synonymous_variant LOW 343A>C Arg115Arg
M0065232 FKDACMBL_00002 837 4 Skin 0.22 protein_coding synonymous_variant LOW 345A>G Arg115Arg
M0065233 FKDACMBL_00002 840 4 Skin 0.22 protein_coding synonymous_variant LOW 348A>G Glu116Glu
M0065234 FKDACMBL_00002 845 4 Skin 0.22 protein_coding missense_variant MODERATE 353A>G Asn118Ser
M0065235 FKDACMBL_00002 849 4 Skin 0.22 protein_coding synonymous_variant LOW 357G>A Glu119Glu
M0065236 FKDACMBL_00002 898 4 Skin 0.22 protein_coding missense_variant MODERATE 406T>G Leu136Val
M0065237 FKDACMBL_00002 927 4 Skin 0.22 protein_coding synonymous_variant LOW 435C>T Ile145Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term