Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2885
  Reference Plasmid   DP1808006652_bin.1__NODE_67_length_7203_cov_0.624437
  Reference Plasmid Size   7203
  Reference Plasmid GC Content   0.59
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0065514 DAIGHJEB_00004 2708 20 Skin 0.22 protein_coding missense_variant MODERATE 196A>G Thr66Ala
M0065515 DAIGHJEB_00004 2785 24 Skin 0.26 protein_coding synonymous_variant LOW 273T>C Asn91Asn
M0065516 DAIGHJEB_00004 2863 22 Skin 0.24 protein_coding synonymous_variant LOW 351A>G Arg117Arg
M0065517 DAIGHJEB_00004 3064 23 Skin 0.25 protein_coding synonymous_variant LOW 552C>T Ser184Ser
M0065518 DAIGHJEB_00004 3079 25 Skin 0.27 protein_coding synonymous_variant LOW 567A>G Glu189Glu
M0065519 DAIGHJEB_00004 3191 28 Skin 0.30 protein_coding synonymous_variant LOW 679T>C Leu227Leu
M0065520 DAIGHJEB_00005 3220 26 Skin 0.28 protein_coding missense_variant MODERATE 13A>G Asn5Asp
M0065521 DAIGHJEB_00005 3565 30 Skin 0.33 protein_coding missense_variant MODERATE 358A>G Ile120Val
M0065522 DAIGHJEB_00005 3598 30 Skin 0.33 protein_coding missense_variant MODERATE 391A>G Ile131Val
M0065523 DAIGHJEB_00005 3615 31 Skin 0.34 protein_coding synonymous_variant LOW 408C>T Ser136Ser
M0065524 DAIGHJEB_00005 3726 23 Skin 0.25 protein_coding synonymous_variant LOW 519T>C Ile173Ile
M0065525 DAIGHJEB_00005 3734 23 Skin 0.25 protein_coding missense_variant MODERATE 527G>A Arg176His
M0065526 DAIGHJEB_00005 3905 25 Skin 0.27 protein_coding missense_variant MODERATE 698A>G Glu233Gly
M0065527 DAIGHJEB_00005 4199 26 Skin 0.28 protein_coding missense_variant MODERATE 992A>G Asn331Ser
M0065528 DAIGHJEB_00005 4611 33 Skin 0.36 protein_coding synonymous_variant LOW 1404G>T Ala468Ala
M0065529 DAIGHJEB_00005 5071 9 Skin 0.10 protein_coding synonymous_variant LOW 1864C>T Leu622Leu
M0065530 DAIGHJEB_00005 5253 19 Skin 0.21 protein_coding synonymous_variant LOW 2046T>C Arg682Arg
M0065531 DAIGHJEB_00005 5400 18 Skin 0.20 protein_coding synonymous_variant LOW 2193T>C Ala731Ala
M0065532 DAIGHJEB_00005 5421 15 Skin 0.16 protein_coding synonymous_variant LOW 2214C>T Gly738Gly
M0065533 DAIGHJEB_00005 5455 16 Skin 0.17 protein_coding missense_variant MODERATE 2248G>T Val750Leu
M0065534 DAIGHJEB_00005 5468 16 Skin 0.17 protein_coding missense_variant MODERATE 2261T>C Val754Ala
M0065535 DAIGHJEB_00002 5553 16 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -3634C>G None
M0065536 DAIGHJEB_00002 5581 17 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -3662T>C None
M0065537 DAIGHJEB_00002 5597 15 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -3678C>G None
M0065538 DAIGHJEB_00002 5601 17 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -3682C>T None
M0065539 DAIGHJEB_00002 5602 17 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -3683G>A None
M0065540 DAIGHJEB_00002 5613 17 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -3694C>T None
M0065541 DAIGHJEB_00002 5682 12 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -3763A>G None
M0065542 DAIGHJEB_00002 2373 14 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -454T>C None
M0065543 DAIGHJEB_00002 2476 19 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -557A>G None
M0065544 DAIGHJEB_00002 2490 23 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -571A>G None
M0065545 DAIGHJEB_00002 2505 5 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -586G>A None
M0065546 DAIGHJEB_00004 2521 22 Skin 0.24 protein_coding synonymous_variant LOW 9T>C Val3Val
M0065547 DAIGHJEB_00005 3369 4 Skin 0.04 protein_coding synonymous_variant LOW 162A>G Ala54Ala
M0065548 DAIGHJEB_00005 4412 32 Skin 0.35 protein_coding missense_variant MODERATE 1205T>C Val402Ala
M0065549 DAIGHJEB_00005 4422 29 Skin 0.32 protein_coding missense_variant MODERATE 1215T>G Ile405Met
M0065550 DAIGHJEB_00005 4456 29 Skin 0.32 protein_coding missense_variant MODERATE 1249G>A Ala417Thr
M0065551 DAIGHJEB_00005 4471 33 Skin 0.36 protein_coding missense_variant MODERATE 1264A>G Thr422Ala
M0065552 DAIGHJEB_00005 4485 32 Skin 0.35 protein_coding synonymous_variant LOW 1278A>G Leu426Leu
M0065553 DAIGHJEB_00005 4719 4 Skin 0.04 protein_coding synonymous_variant LOW 1512T>C Pro504Pro
M0065554 DAIGHJEB_00005 4867 32 Skin 0.35 protein_coding missense_variant MODERATE 1660T>C Phe554Leu
M0065555 DAIGHJEB_00005 4882 35 Skin 0.38 protein_coding missense_variant MODERATE 1675A>G Arg559Gly
M0065556 DAIGHJEB_00005 4905 29 Skin 0.32 protein_coding synonymous_variant LOW 1698G>A Thr566Thr
M0065557 DAIGHJEB_00005 4941 27 Skin 0.29 protein_coding synonymous_variant LOW 1734C>T Ala578Ala
M0065558 DAIGHJEB_00005 4943 7 Skin 0.08 protein_coding missense_variant MODERATE 1736C>T Ser579Phe
M0065559 DAIGHJEB_00005 4946 31 Skin 0.34 protein_coding missense_variant MODERATE 1739G>A Ser580Asn
M0065560 DAIGHJEB_00005 4971 27 Skin 0.29 protein_coding synonymous_variant LOW 1764T>C Asp588Asp
M0065561 DAIGHJEB_00005 5011 25 Skin 0.27 protein_coding missense_variant MODERATE 1804T>A Tyr602Asn
M0065562 DAIGHJEB_00005 5076 26 Skin 0.28 protein_coding synonymous_variant LOW 1869C>T Ser623Ser
M0065563 DAIGHJEB_00005 5082 29 Skin 0.32 protein_coding synonymous_variant LOW 1875T>C Asn625Asn
M0065564 DAIGHJEB_00005 5127 24 Skin 0.26 protein_coding synonymous_variant LOW 1920C>T Asp640Asp
M0065565 DAIGHJEB_00005 5154 25 Skin 0.27 protein_coding missense_variant MODERATE 1947G>A Met649Ile
M0065566 DAIGHJEB_00005 4940 12 Skin 0.13 protein_coding missense_variant MODERATE 1733C>T Ala578Val
M0065567 DAIGHJEB_00006 6367 5 Skin 0.05 protein_coding synonymous_variant LOW 282G>T Gly94Gly
M0065568 DAIGHJEB_00007 7183 26 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -1T>C None
M0065569 DAIGHJEB_00004 2547 8 Skin 0.09 protein_coding missense_variant MODERATE 35T>C Val12Ala
M0065570 DAIGHJEB_00004 2596 8 Skin 0.09 protein_coding synonymous_variant LOW 84C>T Val28Val
M0065571 DAIGHJEB_00005 3336 19 Skin 0.21 protein_coding synonymous_variant LOW 129C>T Ser43Ser
M0065572 DAIGHJEB_00005 4869 33 Skin 0.36 protein_coding synonymous_variant LOW 1662C>T Phe554Phe
M0065573 DAIGHJEB_00002 1695 6 Skin 0.07 protein_coding synonymous_variant LOW 225G>A Gln75Gln
M0065574 DAIGHJEB_00002 1704 6 Skin 0.07 protein_coding synonymous_variant LOW 216T>C Thr72Thr
M0065575 DAIGHJEB_00002 1746 7 Skin 0.08 protein_coding synonymous_variant LOW 174C>T Ala58Ala
M0065576 DAIGHJEB_00002 1788 6 Skin 0.07 protein_coding missense_variant MODERATE 132G>T Gln44His
M0065577 DAIGHJEB_00002 1790 6 Skin 0.07 protein_coding missense_variant MODERATE 130C>G Gln44Glu
M0065578 DAIGHJEB_00002 1982 7 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -63G>A None
M0065579 DAIGHJEB_00002 2029 8 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -110C>G None
M0065580 DAIGHJEB_00002 2034 8 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -115A>G None
M0065581 DAIGHJEB_00002 2037 11 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -118A>G None
M0065582 DAIGHJEB_00002 2064 11 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -145A>G None
M0065583 DAIGHJEB_00002 2066 12 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -147A>G None
M0065584 DAIGHJEB_00002 2081 9 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -162A>G None
M0065585 DAIGHJEB_00002 2087 9 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -168C>T None
M0065586 DAIGHJEB_00002 2093 14 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -174T>C None
M0065587 DAIGHJEB_00002 2096 9 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -177T>G None
M0065588 DAIGHJEB_00002 2097 9 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -178A>G None
M0065589 DAIGHJEB_00003 2136 11 Skin 0.12 protein_coding synonymous_variant LOW 12G>A Leu4Leu
M0065590 DAIGHJEB_00003 2142 11 Skin 0.12 protein_coding synonymous_variant LOW 18A>G Lys6Lys
M0065591 DAIGHJEB_00003 2165 10 Skin 0.11 protein_coding missense_variant MODERATE 41T>C Ile14Thr
M0065592 DAIGHJEB_00003 2213 13 Skin 0.14 protein_coding missense_variant MODERATE 89A>T Gln30Leu
M0065593 DAIGHJEB_00003 2214 11 Skin 0.12 protein_coding synonymous_variant LOW 90A>G Gln30Gln
M0065594 DAIGHJEB_00003 2216 11 Skin 0.12 protein_coding missense_variant MODERATE 92T>A Val31Glu
M0065595 DAIGHJEB_00003 2241 11 Skin 0.12 protein_coding missense_variant MODERATE 117G>C Gln39His
M0065596 DAIGHJEB_00003 2242 15 Skin 0.16 protein_coding missense_variant MODERATE 118G>A Val40Ile
M0065597 DAIGHJEB_00003 2279 12 Skin 0.13 protein_coding missense_variant MODERATE 155A>G Glu52Gly
M0065598 DAIGHJEB_00003 2296 12 Skin 0.13 protein_coding missense_variant MODERATE 172A>G Arg58Gly
M0065599 DAIGHJEB_00003 2300 14 Skin 0.15 protein_coding missense_variant MODERATE 176T>C Val59Ala
M0065600 DAIGHJEB_00003 2303 16 Skin 0.17 protein_coding missense_variant MODERATE 179C>T Thr60Ile
M0065601 DAIGHJEB_00002 1305 7 Skin 0.08 protein_coding synonymous_variant LOW 615C>T Tyr205Tyr
M0065602 DAIGHJEB_00002 1590 6 Skin 0.07 protein_coding missense_variant MODERATE 330G>T Arg110Ser
M0065603 DAIGHJEB_00002 1948 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -29A>G None
M0065604 DAIGHJEB_00002 2503 9 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -584G>A None
M0065605 DAIGHJEB_00005 3710 3 Skin 0.03 protein_coding missense_variant MODERATE 503A>G Lys168Arg
M0065606 DAIGHJEB_00002 1105 4 Skin 0.04 protein_coding missense_variant MODERATE 815C>T Thr272Met
M0065607 DAIGHJEB_00003 2271 9 Skin 0.10 protein_coding synonymous_variant LOW 147A>G Gln49Gln
M0065608 DAIGHJEB_00004 2529 11 Skin 0.12 protein_coding missense_variant MODERATE 17G>A Gly6Asp
M0065609 DAIGHJEB_00005 3574 9 Skin 0.10 protein_coding missense_variant MODERATE 367A>G Lys123Glu
M0065610 DAIGHJEB_00002 2360 5 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -441G>A None
M0065611 DAIGHJEB_00001 178 3 Skin 0.03 protein_coding synonymous_variant LOW 96A>G Pro32Pro
M0065612 DAIGHJEB_00001 549 3 Skin 0.03 protein_coding missense_variant MODERATE 467G>C Gly156Ala
M0065613 DAIGHJEB_00001 643 10 Skin 0.11 protein_coding missense_variant MODERATE 561C>A His187Gln
M0065614 DAIGHJEB_00002 993 8 Skin 0.09 protein_coding synonymous_variant LOW 927G>T Thr309Thr
M0065615 DAIGHJEB_00002 1592 5 Skin 0.05 protein_coding missense_variant MODERATE 328A>G Arg110Gly
M0065616 DAIGHJEB_00005 4948 3 Skin 0.03 protein_coding missense_variant MODERATE 1741A>G Thr581Ala
M0065617 DAIGHJEB_00002 944 4 Skin 0.04 protein_coding missense_variant MODERATE 976G>A Val326Ile
M0065618 DAIGHJEB_00002 1004 4 Skin 0.04 protein_coding missense_variant MODERATE 916C>T Pro306Ser
M0065619 DAIGHJEB_00002 1133 5 Skin 0.05 protein_coding missense_variant MODERATE 787G>C Val263Leu
M0065620 DAIGHJEB_00002 1308 4 Skin 0.04 protein_coding synonymous_variant LOW 612A>G Gly204Gly
M0065621 DAIGHJEB_00002 1341 4 Skin 0.04 protein_coding synonymous_variant LOW 579T>C Asp193Asp
M0065622 DAIGHJEB_00002 1515 4 Skin 0.04 protein_coding synonymous_variant LOW 405C>T Phe135Phe
M0065623 DAIGHJEB_00002 1524 4 Skin 0.04 protein_coding synonymous_variant LOW 396G>A Lys132Lys
M0065624 DAIGHJEB_00002 1596 4 Skin 0.04 protein_coding synonymous_variant LOW 324C>T Ser108Ser
M0065625 DAIGHJEB_00002 1614 4 Skin 0.04 protein_coding synonymous_variant LOW 306C>T Gly102Gly
M0065626 DAIGHJEB_00002 1835 5 Skin 0.05 protein_coding missense_variant MODERATE 85A>C Ser29Arg
M0065627 DAIGHJEB_00005 5158 6 Skin 0.07 protein_coding missense_variant MODERATE 1951C>T Pro651Ser
M0065628 DAIGHJEB_00005 5180 4 Skin 0.04 protein_coding missense_variant MODERATE 1973C>T Ala658Val
M0065629 DAIGHJEB_00004 2734 10 Skin 0.11 protein_coding synonymous_variant LOW 222T>G Gly74Gly
M0065630 DAIGHJEB_00005 3870 3 Skin 0.03 protein_coding synonymous_variant LOW 663C>T Ser221Ser
M0065631 DAIGHJEB_00003 759 4 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -1366C>A None
M0065632 DAIGHJEB_00003 760 4 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -1365C>T None
M0065633 DAIGHJEB_00004 3147 4 Skin 0.04 protein_coding missense_variant MODERATE 635C>T Ala212Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
DAIGHJEB_00002 AEW84325.1|GT4 100 1.36e-285 1 379 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term