Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2888
  Reference Plasmid   DP1808006684_bin.2__NODE_563_length_4553_cov_1.707454
  Reference Plasmid Size   4553
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0065767 KNPCAPKM_00002 1004 4 Skin 0.80 protein_coding synonymous_variant LOW 345T>C Arg115Arg
M0065768 KNPCAPKM_00002 1252 4 Skin 0.80 protein_coding missense_variant MODERATE 593T>G Leu198Arg
M0065769 KNPCAPKM_00002 1283 4 Skin 0.80 protein_coding synonymous_variant LOW 624C>T Arg208Arg
M0065770 KNPCAPKM_00002 1287 4 Skin 0.80 protein_coding synonymous_variant LOW 628C>T Leu210Leu
M0065771 KNPCAPKM_00002 1319 4 Skin 0.80 protein_coding synonymous_variant LOW 660T>C His220His
M0065772 KNPCAPKM_00002 1380 4 Skin 0.80 protein_coding missense_variant MODERATE 721G>A Glu241Lys
M0065773 KNPCAPKM_00003 2011 4 Skin 0.80 protein_coding synonymous_variant LOW 720T>C His240His
M0065774 KNPCAPKM_00003 2020 4 Skin 0.80 protein_coding synonymous_variant LOW 711G>A Gly237Gly
M0065775 KNPCAPKM_00003 2037 4 Skin 0.80 protein_coding synonymous_variant LOW 694T>C Leu232Leu
M0065776 KNPCAPKM_00003 2038 4 Skin 0.80 protein_coding synonymous_variant LOW 693A>G Pro231Pro
M0065777 KNPCAPKM_00003 2055 4 Skin 0.80 protein_coding missense_variant MODERATE 676C>T Arg226Cys
M0065778 KNPCAPKM_00003 2137 4 Skin 0.80 protein_coding synonymous_variant LOW 594G>A Ala198Ala
M0065779 KNPCAPKM_00003 2139 4 Skin 0.80 protein_coding missense_variant MODERATE 592G>A Ala198Thr
M0065780 KNPCAPKM_00003 2146 4 Skin 0.80 protein_coding synonymous_variant LOW 585G>A Gln195Gln
M0065781 KNPCAPKM_00005 3844 4 Skin 0.80 protein_coding synonymous_variant LOW 711C>T Gly237Gly
M0065782 KNPCAPKM_00003 2338 3 Skin 0.60 protein_coding synonymous_variant LOW 393T>C Gly131Gly
M0065783 KNPCAPKM_00003 2406 3 Skin 0.60 protein_coding missense_variant MODERATE 325C>G Leu109Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term