Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2892
  Reference Plasmid   DP1808006693_bin.2__NODE_344_length_3529_cov_0.141983
  Reference Plasmid Size   3529
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0066046 OEAOMLGK_00001 576 6 Skin 0.50 protein_coding synonymous_variant LOW 573G>A Lys191Lys
M0066047 OEAOMLGK_00001 594 7 Skin 0.58 protein_coding synonymous_variant LOW 591T>C Ser197Ser
M0066048 OEAOMLGK_00001 717 7 Skin 0.58 protein_coding synonymous_variant LOW 714A>G Val238Val
M0066049 OEAOMLGK_00001 744 6 Skin 0.50 protein_coding synonymous_variant LOW 741G>A Glu247Glu
M0066050 OEAOMLGK_00001 747 6 Skin 0.50 protein_coding synonymous_variant LOW 744A>C Ala248Ala
M0066051 OEAOMLGK_00001 750 6 Skin 0.50 protein_coding synonymous_variant LOW 747T>C Ala249Ala
M0066052 OEAOMLGK_00001 771 7 Skin 0.58 protein_coding synonymous_variant LOW 768A>G Gly256Gly
M0066053 OEAOMLGK_00001 795 3 Skin 0.25 protein_coding synonymous_variant LOW 792A>G Lys264Lys
M0066054 OEAOMLGK_00001 864 3 Skin 0.25 protein_coding synonymous_variant LOW 861G>A Val287Val
M0066055 OEAOMLGK_00001 885 3 Skin 0.25 protein_coding synonymous_variant LOW 882T>G Ala294Ala
M0066056 OEAOMLGK_00001 894 3 Skin 0.25 protein_coding synonymous_variant LOW 891G>A Leu297Leu
M0066057 OEAOMLGK_00001 909 6 Skin 0.50 protein_coding synonymous_variant LOW 906A>G Gln302Gln
M0066058 OEAOMLGK_00002 1050 11 Skin 0.92 protein_coding start_lost HIGH 1A>G Met1?
M0066059 OEAOMLGK_00002 1055 3 Skin 0.25 protein_coding synonymous_variant LOW 6T>C Ser2Ser
M0066060 OEAOMLGK_00002 1058 3 Skin 0.25 protein_coding synonymous_variant LOW 9G>A Ala3Ala
M0066061 OEAOMLGK_00002 1059 3 Skin 0.25 protein_coding missense_variant MODERATE 10C>G Arg4Gly
M0066062 OEAOMLGK_00002 1109 11 Skin 0.92 protein_coding synonymous_variant LOW 60A>G Gly20Gly
M0066063 OEAOMLGK_00003 1691 7 Skin 0.58 protein_coding upstream_gene_variant MODIFIER -1C>T None
M0066064 OEAOMLGK_00004 2345 4 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -132T>C None
M0066065 OEAOMLGK_00004 2677 5 Skin 0.42 protein_coding synonymous_variant LOW 201A>G Ala67Ala
M0066066 OEAOMLGK_00005 2690 5 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -17C>G None
M0066067 OEAOMLGK_00005 2752 4 Skin 0.33 protein_coding missense_variant MODERATE 46A>G Thr16Ala
M0066068 OEAOMLGK_00005 2805 4 Skin 0.33 protein_coding synonymous_variant LOW 99A>G Val33Val
M0066069 OEAOMLGK_00005 2872 3 Skin 0.25 protein_coding missense_variant MODERATE 166A>G Thr56Ala
M0066070 OEAOMLGK_00005 2892 4 Skin 0.33 protein_coding synonymous_variant LOW 186T>C Ser62Ser
M0066071 OEAOMLGK_00005 2919 9 Skin 0.75 protein_coding synonymous_variant LOW 213C>G Arg71Arg
M0066072 OEAOMLGK_00005 2928 9 Skin 0.75 protein_coding synonymous_variant LOW 222T>C Ala74Ala
M0066073 OEAOMLGK_00005 2929 7 Skin 0.58 protein_coding synonymous_variant LOW 223T>C Leu75Leu
M0066074 OEAOMLGK_00005 2931 9 Skin 0.75 protein_coding synonymous_variant LOW 225A>G Leu75Leu
M0066075 OEAOMLGK_00001 144 5 Skin 0.42 protein_coding synonymous_variant LOW 141A>G Gly47Gly
M0066076 OEAOMLGK_00001 471 5 Skin 0.42 protein_coding synonymous_variant LOW 468C>T Gly156Gly
M0066077 OEAOMLGK_00001 966 6 Skin 0.50 protein_coding synonymous_variant LOW 963T>G Gly321Gly
M0066078 OEAOMLGK_00001 975 9 Skin 0.75 protein_coding synonymous_variant LOW 972A>C Gly324Gly
M0066079 OEAOMLGK_00003 1760 4 Skin 0.33 protein_coding missense_variant MODERATE 69G>C Glu23Asp
M0066080 OEAOMLGK_00004 2551 4 Skin 0.33 protein_coding synonymous_variant LOW 75C>G Thr25Thr
M0066081 OEAOMLGK_00004 2554 4 Skin 0.33 protein_coding synonymous_variant LOW 78T>C His26His
M0066082 OEAOMLGK_00004 2647 3 Skin 0.25 protein_coding synonymous_variant LOW 171C>T Arg57Arg
M0066083 OEAOMLGK_00005 2913 3 Skin 0.25 protein_coding missense_variant MODERATE 207G>C Gln69His
M0066084 OEAOMLGK_00005 3432 6 Skin 0.50 protein_coding synonymous_variant LOW 726G>A Glu242Glu
M0066085 OEAOMLGK_00001 26 3 Skin 0.25 protein_coding missense_variant MODERATE 23G>A Gly8Asp
M0066086 OEAOMLGK_00004 2500 4 Skin 0.33 protein_coding synonymous_variant LOW 24T>C Asp8Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term