Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2898
  Reference Plasmid   DP1808006742_bin.7__NODE_21_length_24496_cov_13.698119
  Reference Plasmid Size   24496
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0066328 ICMFDGLI_00003 1520 19 Skin 0.45 protein_coding synonymous_variant LOW 297T>C Thr99Thr
M0066329 ICMFDGLI_00012 10901 4 Skin 0.10 protein_coding missense_variant MODERATE 449A>G Glu150Gly
M0066330 ICMFDGLI_00019 19713 3 Skin 0.07 protein_coding synonymous_variant LOW 666C>T Arg222Arg
M0066331 ICMFDGLI_00019 19771 4 Skin 0.10 protein_coding missense_variant MODERATE 724A>G Ile242Val
M0066332 ICMFDGLI_00019 19772 4 Skin 0.10 protein_coding missense_variant MODERATE 725T>A Ile242Asn
M0066333 ICMFDGLI_00019 19786 4 Skin 0.10 protein_coding missense_variant MODERATE 739A>G Ser247Gly
M0066334 ICMFDGLI_00019 19804 4 Skin 0.10 protein_coding missense_variant MODERATE 757A>G Asn253Asp
M0066335 ICMFDGLI_00019 20514 4 Skin 0.10 protein_coding missense_variant MODERATE 1467G>T Trp489Cys
M0066336 ICMFDGLI_00020 21251 4 Skin 0.10 protein_coding synonymous_variant LOW 213T>G Ala71Ala
M0066337 ICMFDGLI_00021 21595 4 Skin 0.10 protein_coding missense_variant MODERATE 1154T>A Ile385Asn
M0066338 ICMFDGLI_00006 5768 14 Skin 0.33 protein_coding synonymous_variant LOW 636C>T Gly212Gly
M0066339 ICMFDGLI_00007 5878 14 Skin 0.33 protein_coding synonymous_variant LOW 72A>G Pro24Pro
M0066340 ICMFDGLI_00008 6733 3 Skin 0.07 protein_coding missense_variant MODERATE 169T>C Phe57Leu
M0066341 ICMFDGLI_00008 7081 5 Skin 0.12 protein_coding missense_variant MODERATE 517A>G Lys173Glu
M0066342 ICMFDGLI_00009 7791 4 Skin 0.10 protein_coding missense_variant MODERATE 13A>G Ile5Val
M0066343 ICMFDGLI_00001 118 4 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -70T>G None
M0066344 ICMFDGLI_00001 240 3 Skin 0.07 protein_coding missense_variant MODERATE 53G>A Ser18Asn
M0066345 ICMFDGLI_00001 518 3 Skin 0.07 protein_coding missense_variant MODERATE 331A>C Thr111Pro
M0066346 ICMFDGLI_00001 561 3 Skin 0.07 protein_coding missense_variant MODERATE 374G>T Cys125Phe
M0066347 ICMFDGLI_00004 2097 3 Skin 0.07 protein_coding synonymous_variant LOW 516C>T Gly172Gly
M0066348 ICMFDGLI_00021 22586 3 Skin 0.07 protein_coding synonymous_variant LOW 163C>T Leu55Leu
M0066349 ICMFDGLI_00020 23164 4 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -1701T>C None
M0066350 ICMFDGLI_00022 23333 4 Skin 0.10 protein_coding synonymous_variant LOW 39C>T Arg13Arg
M0066351 ICMFDGLI_00024 24116 3 Skin 0.07 protein_coding synonymous_variant LOW 306T>C Val102Val
M0066352 ICMFDGLI_00004 3079 6 Skin 0.14 protein_coding missense_variant MODERATE 1498G>A Glu500Lys
M0066353 ICMFDGLI_00005 4340 17 Skin 0.40 protein_coding synonymous_variant LOW 390T>C Pro130Pro
M0066354 ICMFDGLI_00005 4601 17 Skin 0.40 protein_coding synonymous_variant LOW 651T>C Asn217Asn
M0066355 ICMFDGLI_00004 3004 5 Skin 0.12 protein_coding missense_variant MODERATE 1423G>A Ala475Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term