Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2903
  Reference Plasmid   DP1808006749_bin.3__NODE_311_length_6929_cov_0.617862
  Reference Plasmid Size   6929
  Reference Plasmid GC Content   0.73
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0066763 CDGHCOPJ_00002 926 3 Skin 0.19 protein_coding missense_variant MODERATE 1105G>C Gly369Arg
M0066764 CDGHCOPJ_00002 1963 4 Skin 0.25 protein_coding missense_variant MODERATE 68C>G Thr23Arg
M0066765 CDGHCOPJ_00002 2003 3 Skin 0.19 protein_coding missense_variant MODERATE 28A>C Ile10Leu
M0066766 CDGHCOPJ_00003 2084 4 Skin 0.25 protein_coding synonymous_variant LOW 1635A>G Arg545Arg
M0066767 CDGHCOPJ_00003 2093 4 Skin 0.25 protein_coding synonymous_variant LOW 1626C>G Ala542Ala
M0066768 CDGHCOPJ_00003 2108 4 Skin 0.25 protein_coding synonymous_variant LOW 1611T>C Asn537Asn
M0066769 CDGHCOPJ_00003 2185 5 Skin 0.31 protein_coding synonymous_variant LOW 1534T>C Leu512Leu
M0066770 CDGHCOPJ_00003 2294 4 Skin 0.25 protein_coding synonymous_variant LOW 1425A>G Thr475Thr
M0066771 CDGHCOPJ_00003 2423 3 Skin 0.19 protein_coding synonymous_variant LOW 1296C>G Leu432Leu
M0066772 CDGHCOPJ_00003 2432 3 Skin 0.19 protein_coding synonymous_variant LOW 1287A>G Ala429Ala
M0066773 CDGHCOPJ_00003 2540 4 Skin 0.25 protein_coding synonymous_variant LOW 1179G>C Gly393Gly
M0066774 CDGHCOPJ_00003 2546 5 Skin 0.31 protein_coding synonymous_variant LOW 1173T>C Asp391Asp
M0066775 CDGHCOPJ_00003 2642 3 Skin 0.19 protein_coding synonymous_variant LOW 1077C>G Ala359Ala
M0066776 CDGHCOPJ_00003 2651 5 Skin 0.31 protein_coding synonymous_variant LOW 1068C>G Leu356Leu
M0066777 CDGHCOPJ_00003 2765 5 Skin 0.31 protein_coding missense_variant MODERATE 954C>G Asp318Glu
M0066778 CDGHCOPJ_00003 3434 3 Skin 0.19 protein_coding synonymous_variant LOW 285T>C Asn95Asn
M0066779 CDGHCOPJ_00003 3599 4 Skin 0.25 protein_coding synonymous_variant LOW 120C>G Val40Val
M0066780 CDGHCOPJ_00003 3668 5 Skin 0.31 protein_coding synonymous_variant LOW 51A>G Val17Val
M0066781 CDGHCOPJ_00004 593 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3188T>A None
M0066782 CDGHCOPJ_00004 626 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3155C>A None
M0066783 CDGHCOPJ_00001 649 3 Skin 0.19 protein_coding synonymous_variant LOW 180C>T Phe60Phe
M0066784 CDGHCOPJ_00001 654 4 Skin 0.25 protein_coding missense_variant MODERATE 175A>G Ile59Val
M0066785 CDGHCOPJ_00002 1584 4 Skin 0.25 protein_coding synonymous_variant LOW 447G>A Val149Val
M0066786 CDGHCOPJ_00003 3170 3 Skin 0.19 protein_coding missense_variant MODERATE 549T>G Asp183Glu
M0066787 CDGHCOPJ_00003 3203 3 Skin 0.19 protein_coding synonymous_variant LOW 516T>C Val172Val
M0066788 CDGHCOPJ_00004 4050 3 Skin 0.19 protein_coding synonymous_variant LOW 270T>C His90His
M0066789 CDGHCOPJ_00004 4548 6 Skin 0.38 protein_coding synonymous_variant LOW 768T>C Ser256Ser
M0066790 CDGHCOPJ_00005 5012 6 Skin 0.38 protein_coding synonymous_variant LOW 99T>C Ile33Ile
M0066791 CDGHCOPJ_00005 5048 6 Skin 0.38 protein_coding synonymous_variant LOW 135C>T Ile45Ile
M0066792 CDGHCOPJ_00005 5065 3 Skin 0.19 protein_coding missense_variant MODERATE 152C>T Ala51Val
M0066793 CDGHCOPJ_00005 5070 5 Skin 0.31 protein_coding missense_variant MODERATE 157C>G Arg53Gly
M0066794 CDGHCOPJ_00005 5252 5 Skin 0.31 protein_coding synonymous_variant LOW 339G>C Ala113Ala
M0066795 CDGHCOPJ_00005 5297 4 Skin 0.25 protein_coding synonymous_variant LOW 384C>T Asp128Asp
M0066796 CDGHCOPJ_00005 5459 6 Skin 0.38 protein_coding synonymous_variant LOW 546A>G Glu182Glu
M0066797 CDGHCOPJ_00005 5483 3 Skin 0.19 protein_coding synonymous_variant LOW 570G>A Val190Val
M0066798 CDGHCOPJ_00006 6035 10 Skin 0.63 protein_coding synonymous_variant LOW 465T>C Ala155Ala
M0066799 CDGHCOPJ_00006 6040 7 Skin 0.44 protein_coding missense_variant MODERATE 460T>G Ser154Ala
M0066800 CDGHCOPJ_00006 6495 9 Skin 0.56 protein_coding missense_variant MODERATE 5C>G Thr2Arg
M0066801 CDGHCOPJ_00002 6600 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4570C>T None
M0066802 CDGHCOPJ_00004 4629 3 Skin 0.19 protein_coding synonymous_variant LOW 849G>A Val283Val
M0066803 CDGHCOPJ_00002 6585 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4555C>T None
M0066804 CDGHCOPJ_00002 6599 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4569C>G None
M0066805 CDGHCOPJ_00004 4602 3 Skin 0.19 protein_coding synonymous_variant LOW 822C>A Gly274Gly
M0066806 CDGHCOPJ_00005 5324 4 Skin 0.25 protein_coding synonymous_variant LOW 411T>C Arg137Arg
M0066807 CDGHCOPJ_00005 5339 4 Skin 0.25 protein_coding synonymous_variant LOW 426T>G Leu142Leu
M0066808 CDGHCOPJ_00005 5363 3 Skin 0.19 protein_coding synonymous_variant LOW 450C>A Gly150Gly
M0066809 CDGHCOPJ_00005 5603 3 Skin 0.19 protein_coding synonymous_variant LOW 690T>C Phe230Phe
M0066810 CDGHCOPJ_00006 6029 3 Skin 0.19 protein_coding synonymous_variant LOW 471C>G Val157Val
M0066811 CDGHCOPJ_00006 6278 5 Skin 0.31 protein_coding synonymous_variant LOW 222A>C Val74Val
M0066812 CDGHCOPJ_00002 6759 6 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4729G>C None
M0066813 CDGHCOPJ_00002 6844 5 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -4814C>A None
M0066814 CDGHCOPJ_00005 5114 5 Skin 0.31 protein_coding missense_variant MODERATE 201C>A Asp67Glu
M0066815 CDGHCOPJ_00005 5144 3 Skin 0.19 protein_coding synonymous_variant LOW 231A>G Ala77Ala
M0066816 CDGHCOPJ_00002 6750 5 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -4720A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term