Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2910
  Reference Plasmid   DP1808006751_bin.8__NODE_41_length_10837_cov_0.941609
  Reference Plasmid Size   10837
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0066941 ICCOMDKJ_00006 5336 3 Skin 0.50 protein_coding missense_variant MODERATE 764G>T Cys255Phe
M0066942 ICCOMDKJ_00006 5348 3 Skin 0.50 protein_coding missense_variant MODERATE 776A>T Asp259Val
M0066943 ICCOMDKJ_00006 5350 3 Skin 0.50 protein_coding missense_variant MODERATE 778G>A Ala260Thr
M0066944 ICCOMDKJ_00006 5396 3 Skin 0.50 protein_coding missense_variant MODERATE 824T>C Ile275Thr
M0066945 ICCOMDKJ_00006 5535 3 Skin 0.50 protein_coding synonymous_variant LOW 963G>C Ala321Ala
M0066946 ICCOMDKJ_00007 7843 4 Skin 0.67 protein_coding missense_variant MODERATE 1325G>C Gly442Ala
M0066947 ICCOMDKJ_00007 7848 4 Skin 0.67 protein_coding missense_variant MODERATE 1330G>A Val444Ile
M0066948 ICCOMDKJ_00007 7899 3 Skin 0.50 protein_coding missense_variant MODERATE 1381A>G Thr461Ala
M0066949 ICCOMDKJ_00007 7982 4 Skin 0.67 protein_coding synonymous_variant LOW 1464G>T Ser488Ser
M0066950 ICCOMDKJ_00007 7988 4 Skin 0.67 protein_coding synonymous_variant LOW 1470C>T Tyr490Tyr
M0066951 ICCOMDKJ_00007 8024 4 Skin 0.67 protein_coding synonymous_variant LOW 1506C>T Ala502Ala
M0066952 ICCOMDKJ_00007 8045 4 Skin 0.67 protein_coding synonymous_variant LOW 1527G>A Glu509Glu
M0066953 ICCOMDKJ_00007 8123 4 Skin 0.67 protein_coding synonymous_variant LOW 1605T>C His535His
M0066954 ICCOMDKJ_00007 8132 4 Skin 0.67 protein_coding synonymous_variant LOW 1614A>G Pro538Pro
M0066955 ICCOMDKJ_00007 8165 3 Skin 0.50 protein_coding synonymous_variant LOW 1647C>T Arg549Arg
M0066956 ICCOMDKJ_00007 8192 3 Skin 0.50 protein_coding synonymous_variant LOW 1674C>T Cys558Cys
M0066957 ICCOMDKJ_00007 8201 4 Skin 0.67 protein_coding synonymous_variant LOW 1683T>C Asp561Asp
M0066958 ICCOMDKJ_00007 8306 3 Skin 0.50 protein_coding synonymous_variant LOW 1788C>T Asn596Asn
M0066959 ICCOMDKJ_00008 8968 3 Skin 0.50 protein_coding missense_variant MODERATE 793G>A Gly265Ser
M0066960 ICCOMDKJ_00008 8995 3 Skin 0.50 protein_coding synonymous_variant LOW 766C>T Leu256Leu
M0066961 ICCOMDKJ_00008 8999 3 Skin 0.50 protein_coding synonymous_variant LOW 762A>G Ala254Ala
M0066962 ICCOMDKJ_00008 9380 3 Skin 0.50 protein_coding synonymous_variant LOW 381C>T Thr127Thr
M0066963 ICCOMDKJ_00006 5722 3 Skin 0.50 protein_coding missense_variant MODERATE 1150A>G Thr384Ala
M0066964 ICCOMDKJ_00006 5723 3 Skin 0.50 protein_coding missense_variant MODERATE 1151C>T Thr384Met
M0066965 ICCOMDKJ_00006 5738 3 Skin 0.50 protein_coding missense_variant MODERATE 1166C>G Thr389Ser
M0066966 ICCOMDKJ_00006 5739 3 Skin 0.50 protein_coding synonymous_variant LOW 1167T>C Thr389Thr
M0066967 ICCOMDKJ_00006 5741 3 Skin 0.50 protein_coding missense_variant MODERATE 1169A>G Asn390Ser
M0066968 ICCOMDKJ_00006 5749 3 Skin 0.50 protein_coding missense_variant MODERATE 1177G>A Ala393Thr
M0066969 ICCOMDKJ_00006 5757 3 Skin 0.50 protein_coding synonymous_variant LOW 1185A>C Thr395Thr
M0066970 ICCOMDKJ_00006 5760 3 Skin 0.50 protein_coding synonymous_variant LOW 1188C>T Arg396Arg
M0066971 ICCOMDKJ_00006 5778 3 Skin 0.50 protein_coding synonymous_variant LOW 1206C>T Tyr402Tyr
M0066972 ICCOMDKJ_00006 5782 3 Skin 0.50 protein_coding missense_variant MODERATE 1210C>G Gln404Glu
M0066973 ICCOMDKJ_00006 5817 3 Skin 0.50 protein_coding synonymous_variant LOW 1245T>A Arg415Arg
M0066974 ICCOMDKJ_00006 5821 3 Skin 0.50 protein_coding missense_variant MODERATE 1249C>G Leu417Val
M0066975 ICCOMDKJ_00006 5835 3 Skin 0.50 protein_coding synonymous_variant LOW 1263C>G Pro421Pro
M0066976 ICCOMDKJ_00006 5837 3 Skin 0.50 protein_coding missense_variant MODERATE 1265G>C Ser422Thr
M0066977 ICCOMDKJ_00006 5838 3 Skin 0.50 protein_coding synonymous_variant LOW 1266C>T Ser422Ser
M0066978 ICCOMDKJ_00006 5842 3 Skin 0.50 protein_coding missense_variant MODERATE 1270G>T Ala424Ser
M0066979 ICCOMDKJ_00007 7922 3 Skin 0.50 protein_coding synonymous_variant LOW 1404C>T Tyr468Tyr
M0066980 ICCOMDKJ_00007 7937 3 Skin 0.50 protein_coding synonymous_variant LOW 1419G>A Glu473Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term