Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2916
  Reference Plasmid   DP1808006754_bin.23__NODE_974_length_6338_cov_0.473954
  Reference Plasmid Size   6338
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0067009 AADCINMC_00002 2885 3 Skin 0.60 protein_coding synonymous_variant LOW 2385C>T His795His
M0067010 AADCINMC_00002 3037 4 Skin 0.80 protein_coding missense_variant MODERATE 2537A>C Glu846Ala
M0067011 AADCINMC_00002 3052 4 Skin 0.80 protein_coding missense_variant MODERATE 2552A>G His851Arg
M0067012 AADCINMC_00002 3054 4 Skin 0.80 protein_coding missense_variant MODERATE 2554C>A Leu852Met
M0067013 AADCINMC_00002 3106 4 Skin 0.80 protein_coding missense_variant MODERATE 2606A>C Gln869Pro
M0067014 AADCINMC_00003 3171 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -61C>G None
M0067015 AADCINMC_00003 3209 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -23G>A None
M0067016 AADCINMC_00003 3453 3 Skin 0.60 protein_coding synonymous_variant LOW 222A>G Arg74Arg
M0067017 AADCINMC_00003 3780 3 Skin 0.60 protein_coding synonymous_variant LOW 549C>G Val183Val
M0067018 AADCINMC_00003 3862 3 Skin 0.60 protein_coding missense_variant MODERATE 631A>G Ser211Gly
M0067019 AADCINMC_00003 3865 3 Skin 0.60 protein_coding synonymous_variant LOW 634C>T Leu212Leu
M0067020 AADCINMC_00006 4037 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -927C>T None
M0067021 AADCINMC_00006 4052 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -912A>C None
M0067022 AADCINMC_00005 4356 3 Skin 0.60 protein_coding synonymous_variant LOW 486G>C Leu162Leu
M0067023 AADCINMC_00005 4383 3 Skin 0.60 protein_coding synonymous_variant LOW 459T>C Gly153Gly
M0067024 AADCINMC_00005 4518 3 Skin 0.60 protein_coding synonymous_variant LOW 324C>G Leu108Leu
M0067025 AADCINMC_00005 4897 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -56G>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term