Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2932
  Reference Plasmid   DP1808006828_bin.6__NODE_399_length_5307_cov_0.431452
  Reference Plasmid Size   5307
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0067406 KHFIBHKF_00003 3470 5 Skin 0.71 protein_coding missense_variant MODERATE 769A>G Met257Val
M0067407 KHFIBHKF_00005 5170 6 Skin 0.86 protein_coding stop_lost&splice_region_variant HIGH 791A>G Ter264Trpext*?
M0067408 KHFIBHKF_00002 1664 3 Skin 0.43 protein_coding missense_variant MODERATE 958T>G Ser320Ala
M0067409 KHFIBHKF_00002 1668 3 Skin 0.43 protein_coding synonymous_variant LOW 954A>C Thr318Thr
M0067410 KHFIBHKF_00002 1671 3 Skin 0.43 protein_coding synonymous_variant LOW 951T>C Phe317Phe
M0067411 KHFIBHKF_00002 1692 3 Skin 0.43 protein_coding synonymous_variant LOW 930C>T Phe310Phe
M0067412 KHFIBHKF_00002 1784 4 Skin 0.57 protein_coding missense_variant MODERATE 838A>G Ser280Gly
M0067413 KHFIBHKF_00002 1797 3 Skin 0.43 protein_coding synonymous_variant LOW 825C>G Gly275Gly
M0067414 KHFIBHKF_00002 1810 3 Skin 0.43 protein_coding missense_variant MODERATE 812G>C Gly271Ala
M0067415 KHFIBHKF_00002 1812 3 Skin 0.43 protein_coding synonymous_variant LOW 810G>T Ala270Ala
M0067416 KHFIBHKF_00002 1826 3 Skin 0.43 protein_coding missense_variant MODERATE 796A>G Ile266Val
M0067417 KHFIBHKF_00002 1839 3 Skin 0.43 protein_coding synonymous_variant LOW 783G>A Gly261Gly
M0067418 KHFIBHKF_00002 1851 3 Skin 0.43 protein_coding synonymous_variant LOW 771G>A Ala257Ala
M0067419 KHFIBHKF_00002 1855 3 Skin 0.43 protein_coding missense_variant MODERATE 767C>G Ala256Gly
M0067420 KHFIBHKF_00002 1856 3 Skin 0.43 protein_coding missense_variant MODERATE 766G>A Ala256Thr
M0067421 KHFIBHKF_00002 1923 3 Skin 0.43 protein_coding synonymous_variant LOW 699C>G Pro233Pro
M0067422 KHFIBHKF_00002 1965 3 Skin 0.43 protein_coding synonymous_variant LOW 657C>T His219His
M0067423 KHFIBHKF_00002 1982 3 Skin 0.43 protein_coding synonymous_variant LOW 640C>T Leu214Leu
M0067424 KHFIBHKF_00002 2064 3 Skin 0.43 protein_coding synonymous_variant LOW 558A>C Ala186Ala
M0067425 KHFIBHKF_00002 2067 3 Skin 0.43 protein_coding synonymous_variant LOW 555G>C Ala185Ala
M0067426 KHFIBHKF_00002 2130 3 Skin 0.43 protein_coding synonymous_variant LOW 492C>A Pro164Pro
M0067427 KHFIBHKF_00002 2142 3 Skin 0.43 protein_coding synonymous_variant LOW 480G>A Leu160Leu
M0067428 KHFIBHKF_00002 2520 3 Skin 0.43 protein_coding synonymous_variant LOW 102C>T Gly34Gly
M0067429 KHFIBHKF_00002 2553 3 Skin 0.43 protein_coding synonymous_variant LOW 69C>T Thr23Thr
M0067430 KHFIBHKF_00001 2643 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1224A>G None
M0067431 KHFIBHKF_00003 3480 3 Skin 0.43 protein_coding missense_variant MODERATE 779G>A Ser260Asn
M0067432 KHFIBHKF_00001 3699 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2280T>C None
M0067433 KHFIBHKF_00001 3701 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2282T>A None
M0067434 KHFIBHKF_00001 3740 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2321C>T None
M0067435 KHFIBHKF_00004 3982 3 Skin 0.43 protein_coding synonymous_variant LOW 165C>T Ala55Ala
M0067436 KHFIBHKF_00004 4189 3 Skin 0.43 protein_coding synonymous_variant LOW 372G>C Thr124Thr
M0067437 KHFIBHKF_00004 4195 3 Skin 0.43 protein_coding synonymous_variant LOW 378A>T Ala126Ala
M0067438 KHFIBHKF_00004 4289 3 Skin 0.43 protein_coding missense_variant MODERATE 472G>T Ala158Ser
M0067439 KHFIBHKF_00005 4976 3 Skin 0.43 protein_coding synonymous_variant LOW 597C>G Leu199Leu
M0067440 KHFIBHKF_00005 5033 3 Skin 0.43 protein_coding synonymous_variant LOW 654A>C Thr218Thr
M0067441 KHFIBHKF_00005 5069 3 Skin 0.43 protein_coding synonymous_variant LOW 690C>T His230His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term