Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2933
  Reference Plasmid   DP1808006828_bin.6__NODE_407_length_5273_cov_0.209123
  Reference Plasmid Size   5273
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0067442 LEJNKKBA_00001 430 8 Skin 0.62 protein_coding synonymous_variant LOW 414T>C Pro138Pro
M0067443 LEJNKKBA_00001 715 6 Skin 0.46 protein_coding synonymous_variant LOW 129T>C Ile43Ile
M0067444 LEJNKKBA_00002 1298 8 Skin 0.62 protein_coding missense_variant MODERATE 142A>G Arg48Gly
M0067445 LEJNKKBA_00003 1843 4 Skin 0.31 protein_coding missense_variant MODERATE 1864G>A Ala622Thr
M0067446 LEJNKKBA_00003 2384 6 Skin 0.46 protein_coding synonymous_variant LOW 1323T>G Ser441Ser
M0067447 LEJNKKBA_00003 2408 6 Skin 0.46 protein_coding synonymous_variant LOW 1299T>C Thr433Thr
M0067448 LEJNKKBA_00003 2458 4 Skin 0.31 protein_coding missense_variant MODERATE 1249A>G Thr417Ala
M0067449 LEJNKKBA_00003 2525 4 Skin 0.31 protein_coding synonymous_variant LOW 1182A>C Arg394Arg
M0067450 LEJNKKBA_00003 2559 5 Skin 0.38 protein_coding missense_variant MODERATE 1148T>C Val383Ala
M0067451 LEJNKKBA_00003 2582 5 Skin 0.38 protein_coding synonymous_variant LOW 1125C>G Leu375Leu
M0067452 LEJNKKBA_00003 2757 4 Skin 0.31 protein_coding missense_variant MODERATE 950C>T Pro317Leu
M0067453 LEJNKKBA_00003 3347 6 Skin 0.46 protein_coding synonymous_variant LOW 360C>G Ala120Ala
M0067454 LEJNKKBA_00003 3353 6 Skin 0.46 protein_coding missense_variant MODERATE 354G>C Leu118Phe
M0067455 LEJNKKBA_00003 3355 6 Skin 0.46 protein_coding synonymous_variant LOW 352T>C Leu118Leu
M0067456 LEJNKKBA_00003 3362 6 Skin 0.46 protein_coding synonymous_variant LOW 345C>G Val115Val
M0067457 LEJNKKBA_00003 3467 4 Skin 0.31 protein_coding synonymous_variant LOW 240C>G Ala80Ala
M0067458 LEJNKKBA_00003 3554 4 Skin 0.31 protein_coding missense_variant MODERATE 153C>G Asn51Lys
M0067459 LEJNKKBA_00003 3555 4 Skin 0.31 protein_coding missense_variant MODERATE 152A>G Asn51Ser
M0067460 LEJNKKBA_00003 3565 4 Skin 0.31 protein_coding missense_variant MODERATE 142A>G Asn48Asp
M0067461 LEJNKKBA_00003 3567 4 Skin 0.31 protein_coding missense_variant MODERATE 140T>C Val47Ala
M0067462 LEJNKKBA_00003 3571 4 Skin 0.31 protein_coding missense_variant MODERATE 136G>A Ala46Thr
M0067463 LEJNKKBA_00003 3657 3 Skin 0.23 protein_coding missense_variant MODERATE 50T>C Val17Ala
M0067464 LEJNKKBA_00001 3738 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -2895T>C None
M0067465 LEJNKKBA_00004 3773 3 Skin 0.23 protein_coding missense_variant MODERATE 1495T>G Ser499Ala
M0067466 LEJNKKBA_00004 3864 3 Skin 0.23 protein_coding synonymous_variant LOW 1404G>A Gly468Gly
M0067467 LEJNKKBA_00004 3909 3 Skin 0.23 protein_coding synonymous_variant LOW 1359C>T Ala453Ala
M0067468 LEJNKKBA_00004 3924 3 Skin 0.23 protein_coding synonymous_variant LOW 1344C>G Ser448Ser
M0067469 LEJNKKBA_00004 3981 3 Skin 0.23 protein_coding synonymous_variant LOW 1287A>G Gln429Gln
M0067470 LEJNKKBA_00003 3260 4 Skin 0.31 protein_coding synonymous_variant LOW 447G>A Glu149Glu
M0067471 LEJNKKBA_00003 3302 5 Skin 0.38 protein_coding synonymous_variant LOW 405T>C Gly135Gly
M0067472 LEJNKKBA_00002 1194 3 Skin 0.23 protein_coding synonymous_variant LOW 246T>C Ser82Ser
M0067473 LEJNKKBA_00002 1265 4 Skin 0.31 protein_coding missense_variant MODERATE 175G>T Gly59Trp
M0067474 LEJNKKBA_00002 1235 4 Skin 0.31 protein_coding missense_variant MODERATE 205G>A Gly69Ser
M0067475 LEJNKKBA_00003 2141 4 Skin 0.31 protein_coding synonymous_variant LOW 1566T>C Ser522Ser
M0067476 LEJNKKBA_00003 2548 3 Skin 0.23 protein_coding missense_variant MODERATE 1159G>A Asp387Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term