Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2951
  Reference Plasmid   DS1912041100-1_bin.11__k141_48646
  Reference Plasmid Size   5334
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0067964 NABCNDNJ_00004 2946 4 Skin 0.80 protein_coding synonymous_variant LOW 252A>C Thr84Thr
M0067965 NABCNDNJ_00004 2967 4 Skin 0.80 protein_coding synonymous_variant LOW 231T>C Gly77Gly
M0067966 NABCNDNJ_00005 3578 3 Skin 0.60 protein_coding synonymous_variant LOW 265T>C Leu89Leu
M0067967 NABCNDNJ_00005 3961 3 Skin 0.60 protein_coding synonymous_variant LOW 648A>G Ala216Ala
M0067968 NABCNDNJ_00005 4045 3 Skin 0.60 protein_coding synonymous_variant LOW 732C>G Ala244Ala
M0067969 NABCNDNJ_00005 4081 3 Skin 0.60 protein_coding synonymous_variant LOW 768A>G Ala256Ala
M0067970 NABCNDNJ_00005 4132 3 Skin 0.60 protein_coding synonymous_variant LOW 819C>A Ala273Ala
M0067971 NABCNDNJ_00006 4492 5 Skin 1.00 protein_coding synonymous_variant LOW 477T>C Cys159Cys
M0067972 NABCNDNJ_00006 4874 3 Skin 0.60 protein_coding missense_variant MODERATE 95A>G Asp32Gly
M0067973 NABCNDNJ_00006 4891 3 Skin 0.60 protein_coding synonymous_variant LOW 78G>A Pro26Pro
M0067974 NABCNDNJ_00006 4915 3 Skin 0.60 protein_coding missense_variant MODERATE 54C>A Asn18Lys
M0067975 NABCNDNJ_00006 4916 4 Skin 0.80 protein_coding missense_variant MODERATE 53A>G Asn18Ser
M0067976 NABCNDNJ_00006 4917 4 Skin 0.80 protein_coding missense_variant MODERATE 52A>G Asn18Asp
M0067977 NABCNDNJ_00006 4921 3 Skin 0.60 protein_coding synonymous_variant LOW 48T>G Leu16Leu
M0067978 NABCNDNJ_00001 4969 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4287C>G None
M0067979 NABCNDNJ_00001 4997 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4315C>T None
M0067980 NABCNDNJ_00001 5000 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4318G>A None
M0067981 NABCNDNJ_00001 5037 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -4355G>A None
M0067982 NABCNDNJ_00001 5041 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -4359G>A None
M0067983 NABCNDNJ_00001 5042 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -4360G>A None
M0067984 NABCNDNJ_00001 5064 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -4382G>A None
M0067985 NABCNDNJ_00001 5065 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -4383T>C None
M0067986 NABCNDNJ_00001 5142 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -4460T>C None
M0067987 NABCNDNJ_00003 1513 3 Skin 0.60 protein_coding missense_variant MODERATE 221C>G Thr74Ser
M0067988 NABCNDNJ_00003 1993 3 Skin 0.60 protein_coding missense_variant MODERATE 701G>A Gly234Asp
M0067989 NABCNDNJ_00003 1997 3 Skin 0.60 protein_coding synonymous_variant LOW 705T>G Leu235Leu
M0067990 NABCNDNJ_00004 2275 4 Skin 0.80 protein_coding stop_lost&splice_region_variant HIGH 923A>C Ter308Serext*?
M0067991 NABCNDNJ_00004 2313 4 Skin 0.80 protein_coding synonymous_variant LOW 885C>G Ser295Ser
M0067992 NABCNDNJ_00004 2409 3 Skin 0.60 protein_coding synonymous_variant LOW 789T>G Ala263Ala
M0067993 NABCNDNJ_00004 2418 3 Skin 0.60 protein_coding synonymous_variant LOW 780G>T Gly260Gly
M0067994 NABCNDNJ_00004 2490 3 Skin 0.60 protein_coding synonymous_variant LOW 708A>C Arg236Arg
M0067995 NABCNDNJ_00004 2517 3 Skin 0.60 protein_coding synonymous_variant LOW 681C>T Arg227Arg
M0067996 NABCNDNJ_00004 2547 4 Skin 0.80 protein_coding synonymous_variant LOW 651C>G Thr217Thr
M0067997 NABCNDNJ_00004 2550 4 Skin 0.80 protein_coding synonymous_variant LOW 648G>A Ser216Ser
M0067998 NABCNDNJ_00004 2973 3 Skin 0.60 protein_coding synonymous_variant LOW 225G>T Arg75Arg
M0067999 NABCNDNJ_00005 3868 4 Skin 0.80 protein_coding synonymous_variant LOW 555A>C Arg185Arg
M0068000 NABCNDNJ_00006 4738 3 Skin 0.60 protein_coding synonymous_variant LOW 231T>G Leu77Leu
M0068001 NABCNDNJ_00006 4745 3 Skin 0.60 protein_coding missense_variant MODERATE 224T>C Val75Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term