Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2952
  Reference Plasmid   DS1912041100-1_bin.11__k141_74560
  Reference Plasmid Size   7274
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0068002 EDEKLPGN_00001 1228 3 Skin 0.60 protein_coding synonymous_variant LOW 273C>T Gly91Gly
M0068003 EDEKLPGN_00001 2262 3 Skin 0.60 protein_coding missense_variant MODERATE 1307G>A Arg436Lys
M0068004 EDEKLPGN_00002 4209 3 Skin 0.60 protein_coding synonymous_variant LOW 840G>A Pro280Pro
M0068005 EDEKLPGN_00002 4338 3 Skin 0.60 protein_coding synonymous_variant LOW 969C>T Leu323Leu
M0068006 EDEKLPGN_00002 4462 5 Skin 1.00 protein_coding missense_variant MODERATE 1093C>A Leu365Ile
M0068007 EDEKLPGN_00002 4614 4 Skin 0.80 protein_coding synonymous_variant LOW 1245G>A Ala415Ala
M0068008 EDEKLPGN_00003 4855 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -6C>T None
M0068009 EDEKLPGN_00003 4858 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -3C>T None
M0068010 EDEKLPGN_00003 4866 3 Skin 0.60 protein_coding synonymous_variant LOW 6C>T Asp2Asp
M0068011 EDEKLPGN_00003 5287 4 Skin 0.80 protein_coding synonymous_variant LOW 427C>T Leu143Leu
M0068012 EDEKLPGN_00003 5238 3 Skin 0.60 protein_coding synonymous_variant LOW 378T>C His126His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term