Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2954
  Reference Plasmid   DS1912041100-1_bin.11__k141_76380
  Reference Plasmid Size   6150
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0068017 GEJHFMMJ_00001 192 4 Skin 0.80 protein_coding missense_variant MODERATE 146G>A Arg49Lys
M0068018 GEJHFMMJ_00001 676 3 Skin 0.60 protein_coding synonymous_variant LOW 630G>C Pro210Pro
M0068019 GEJHFMMJ_00001 745 4 Skin 0.80 protein_coding synonymous_variant LOW 699G>A Glu233Glu
M0068020 GEJHFMMJ_00001 747 5 Skin 1.00 protein_coding missense_variant MODERATE 701T>A Val234Glu
M0068021 GEJHFMMJ_00001 748 4 Skin 0.80 protein_coding synonymous_variant LOW 702G>T Val234Val
M0068022 GEJHFMMJ_00001 769 5 Skin 1.00 protein_coding synonymous_variant LOW 723G>T Ala241Ala
M0068023 GEJHFMMJ_00001 778 5 Skin 1.00 protein_coding synonymous_variant LOW 732G>C Pro244Pro
M0068024 GEJHFMMJ_00001 781 5 Skin 1.00 protein_coding synonymous_variant LOW 735A>T Gly245Gly
M0068025 GEJHFMMJ_00001 787 5 Skin 1.00 protein_coding synonymous_variant LOW 741G>A Ala247Ala
M0068026 GEJHFMMJ_00001 793 3 Skin 0.60 protein_coding synonymous_variant LOW 747C>T Asn249Asn
M0068027 GEJHFMMJ_00001 1333 4 Skin 0.80 protein_coding synonymous_variant LOW 1287T>C Gly429Gly
M0068028 GEJHFMMJ_00001 1894 4 Skin 0.80 protein_coding synonymous_variant LOW 1848T>C Arg616Arg
M0068029 GEJHFMMJ_00001 1972 4 Skin 0.80 protein_coding synonymous_variant LOW 1926T>G Val642Val
M0068030 GEJHFMMJ_00001 2830 3 Skin 0.60 protein_coding synonymous_variant LOW 2784A>G Glu928Glu
M0068031 GEJHFMMJ_00001 2859 5 Skin 1.00 protein_coding missense_variant MODERATE 2813G>C Gly938Ala
M0068032 GEJHFMMJ_00001 3079 4 Skin 0.80 protein_coding synonymous_variant LOW 3033A>G Val1011Val
M0068033 GEJHFMMJ_00001 3238 3 Skin 0.60 protein_coding synonymous_variant LOW 3192G>A Ala1064Ala
M0068034 GEJHFMMJ_00001 3863 3 Skin 0.60 protein_coding missense_variant MODERATE 3817G>A Val1273Ile
M0068035 GEJHFMMJ_00001 4075 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *48A>G None
M0068036 GEJHFMMJ_00001 4137 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *110C>T None
M0068037 GEJHFMMJ_00001 4143 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *116T>C None
M0068038 GEJHFMMJ_00001 4149 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *122T>G None
M0068039 GEJHFMMJ_00001 4152 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *125C>G None
M0068040 GEJHFMMJ_00001 4294 5 Skin 1.00 protein_coding downstream_gene_variant MODIFIER *267C>T None
M0068041 GEJHFMMJ_00001 4440 3 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *413C>A None
M0068042 GEJHFMMJ_00001 4918 5 Skin 1.00 protein_coding downstream_gene_variant MODIFIER *891A>G None
M0068043 GEJHFMMJ_00001 4920 5 Skin 1.00 protein_coding downstream_gene_variant MODIFIER *893T>C None
M0068044 GEJHFMMJ_00001 1192 3 Skin 0.60 protein_coding synonymous_variant LOW 1146A>G Gln382Gln
M0068045 GEJHFMMJ_00001 1210 3 Skin 0.60 protein_coding synonymous_variant LOW 1164C>G Leu388Leu
M0068046 GEJHFMMJ_00001 1228 3 Skin 0.60 protein_coding synonymous_variant LOW 1182C>G Thr394Thr
M0068047 GEJHFMMJ_00001 1273 3 Skin 0.60 protein_coding synonymous_variant LOW 1227C>T Arg409Arg
M0068048 GEJHFMMJ_00001 1275 3 Skin 0.60 protein_coding missense_variant MODERATE 1229T>C Val410Ala
M0068049 GEJHFMMJ_00001 1635 3 Skin 0.60 protein_coding missense_variant MODERATE 1589G>A Arg530Gln
M0068050 GEJHFMMJ_00001 2644 3 Skin 0.60 protein_coding synonymous_variant LOW 2598C>G Gly866Gly
M0068051 GEJHFMMJ_00001 3172 3 Skin 0.60 protein_coding synonymous_variant LOW 3126A>C Ala1042Ala
M0068052 GEJHFMMJ_00001 3175 3 Skin 0.60 protein_coding synonymous_variant LOW 3129G>T Gly1043Gly
M0068053 GEJHFMMJ_00001 3178 3 Skin 0.60 protein_coding synonymous_variant LOW 3132A>G Glu1044Glu
M0068054 GEJHFMMJ_00001 5125 4 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *1098T>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term