Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2964
  Reference Plasmid   DS1912041108-1_bin.5__k141_15494
  Reference Plasmid Size   12351
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0068628 POMDMKCI_00010 10441 3 Skin 0.43 protein_coding missense_variant MODERATE 899G>A Gly300Asp
M0068629 POMDMKCI_00010 10475 3 Skin 0.43 protein_coding synonymous_variant LOW 933A>G Leu311Leu
M0068630 POMDMKCI_00002 776 4 Skin 0.57 protein_coding synonymous_variant LOW 348C>A Ile116Ile
M0068631 POMDMKCI_00003 2964 6 Skin 0.86 protein_coding synonymous_variant LOW 1107A>C Ile369Ile
M0068632 POMDMKCI_00003 3013 6 Skin 0.86 protein_coding missense_variant MODERATE 1156G>A Gly386Ser
M0068633 POMDMKCI_00006 3863 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -1703C>A None
M0068634 POMDMKCI_00005 4832 4 Skin 0.57 protein_coding synonymous_variant LOW 366C>A Gly122Gly
M0068635 POMDMKCI_00005 4835 4 Skin 0.57 protein_coding synonymous_variant LOW 363T>C Gly121Gly
M0068636 POMDMKCI_00005 4838 4 Skin 0.57 protein_coding synonymous_variant LOW 360A>C Ala120Ala
M0068637 POMDMKCI_00005 4841 4 Skin 0.57 protein_coding synonymous_variant LOW 357C>T Phe119Phe
M0068638 POMDMKCI_00006 5727 4 Skin 0.57 protein_coding synonymous_variant LOW 162A>G Ala54Ala
M0068639 POMDMKCI_00006 5808 3 Skin 0.43 protein_coding synonymous_variant LOW 243C>G Pro81Pro
M0068640 POMDMKCI_00006 5823 3 Skin 0.43 protein_coding synonymous_variant LOW 258G>C Gly86Gly
M0068641 POMDMKCI_00006 6162 4 Skin 0.57 protein_coding synonymous_variant LOW 597C>G Leu199Leu
M0068642 POMDMKCI_00006 6208 3 Skin 0.43 protein_coding missense_variant MODERATE 643A>G Ser215Gly
M0068643 POMDMKCI_00006 6243 3 Skin 0.43 protein_coding synonymous_variant LOW 678C>G Ser226Ser
M0068644 POMDMKCI_00006 6246 3 Skin 0.43 protein_coding synonymous_variant LOW 681A>C Ala227Ala
M0068645 POMDMKCI_00006 6738 3 Skin 0.43 protein_coding synonymous_variant LOW 1173G>A Leu391Leu
M0068646 POMDMKCI_00007 8174 3 Skin 0.43 protein_coding synonymous_variant LOW 1272A>G Ala424Ala
M0068647 POMDMKCI_00007 8186 3 Skin 0.43 protein_coding synonymous_variant LOW 1284C>A Gly428Gly
M0068648 POMDMKCI_00005 8316 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3119T>G None
M0068649 POMDMKCI_00005 8318 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3121G>A None
M0068650 POMDMKCI_00002 467 3 Skin 0.43 protein_coding synonymous_variant LOW 39C>A Gly13Gly
M0068651 POMDMKCI_00002 1221 4 Skin 0.57 protein_coding synonymous_variant LOW 793A>C Arg265Arg
M0068652 POMDMKCI_00006 3563 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2003A>C None
M0068653 POMDMKCI_00006 4475 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1091A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
POMDMKCI_00003 QPS84145.1|GT4 99.8 4.57000001178638e-316 1 424 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term