Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2969
  Reference Plasmid   DS1912042263-1_bin.3__k141_19493
  Reference Plasmid Size   5532
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0068714 GBKCNCAA_00001 35 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -831C>G None
M0068715 GBKCNCAA_00001 74 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -792C>T None
M0068716 GBKCNCAA_00001 428 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -438G>A None
M0068717 GBKCNCAA_00001 604 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -262T>C None
M0068718 GBKCNCAA_00001 988 3 Skin 0.60 protein_coding synonymous_variant LOW 123C>T Arg41Arg
M0068719 GBKCNCAA_00001 1366 3 Skin 0.60 protein_coding synonymous_variant LOW 501G>C Gly167Gly
M0068720 GBKCNCAA_00001 1561 5 Skin 1.00 protein_coding synonymous_variant LOW 696C>A Gly232Gly
M0068721 GBKCNCAA_00001 1618 4 Skin 0.80 protein_coding synonymous_variant LOW 753G>A Ser251Ser
M0068722 GBKCNCAA_00003 3394 3 Skin 0.60 protein_coding missense_variant MODERATE 190C>A Leu64Met
M0068723 GBKCNCAA_00003 3401 3 Skin 0.60 protein_coding missense_variant MODERATE 197G>C Gly66Ala
M0068724 GBKCNCAA_00004 4148 3 Skin 0.60 protein_coding synonymous_variant LOW 108A>G Gln36Gln
M0068725 GBKCNCAA_00004 4149 3 Skin 0.60 protein_coding synonymous_variant LOW 109C>T Leu37Leu
M0068726 GBKCNCAA_00004 4202 3 Skin 0.60 protein_coding missense_variant MODERATE 162A>T Glu54Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term