Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2972
  Reference Plasmid   DS1912044172-1_bin.4__k141_21966
  Reference Plasmid Size   3911
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0068731 LHFKLLGB_00003 111 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -1538T>C None
M0068732 LHFKLLGB_00003 289 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1360A>G None
M0068733 LHFKLLGB_00001 1029 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -44T>C None
M0068734 LHFKLLGB_00001 1144 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -159C>T None
M0068735 LHFKLLGB_00002 1287 4 Skin 0.67 protein_coding synonymous_variant LOW 291C>A Leu97Leu
M0068736 LHFKLLGB_00003 1777 5 Skin 0.83 protein_coding synonymous_variant LOW 129C>G Arg43Arg
M0068737 LHFKLLGB_00003 1987 4 Skin 0.67 protein_coding missense_variant MODERATE 339T>G Phe113Leu
M0068738 LHFKLLGB_00003 2548 4 Skin 0.67 protein_coding synonymous_variant LOW 900G>A Ala300Ala
M0068739 LHFKLLGB_00003 2521 3 Skin 0.50 protein_coding synonymous_variant LOW 873G>A Lys291Lys
M0068740 LHFKLLGB_00001 2786 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -1801C>G None
M0068741 LHFKLLGB_00001 2855 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1870T>G None
M0068742 LHFKLLGB_00004 2894 4 Skin 0.67 protein_coding missense_variant MODERATE 5A>C Asn2Thr
M0068743 LHFKLLGB_00004 3294 3 Skin 0.50 protein_coding synonymous_variant LOW 405A>G Gly135Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term