Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2975
  Reference Plasmid   DSKIN0021-1_bin.6__k141_20168
  Reference Plasmid Size   10911
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0068781 AADJNCJI_00001 865 4 Skin 0.80 protein_coding synonymous_variant LOW 147T>G Val49Val
M0068782 AADJNCJI_00002 1299 4 Skin 0.80 protein_coding missense_variant MODERATE 955C>G Leu319Val
M0068783 AADJNCJI_00002 2017 4 Skin 0.80 protein_coding synonymous_variant LOW 237C>T Tyr79Tyr
M0068784 AADJNCJI_00002 2020 4 Skin 0.80 protein_coding synonymous_variant LOW 234A>C Arg78Arg
M0068785 AADJNCJI_00002 2044 4 Skin 0.80 protein_coding synonymous_variant LOW 210T>C Gly70Gly
M0068786 AADJNCJI_00002 2074 3 Skin 0.60 protein_coding synonymous_variant LOW 180A>C Ile60Ile
M0068787 AADJNCJI_00002 2107 4 Skin 0.80 protein_coding missense_variant MODERATE 147C>A Asp49Glu
M0068788 AADJNCJI_00002 2119 4 Skin 0.80 protein_coding synonymous_variant LOW 135G>C Gly45Gly
M0068789 AADJNCJI_00002 2137 4 Skin 0.80 protein_coding synonymous_variant LOW 117C>T Arg39Arg
M0068790 AADJNCJI_00002 2144 4 Skin 0.80 protein_coding missense_variant MODERATE 110C>A Pro37His
M0068791 AADJNCJI_00003 2850 4 Skin 0.80 protein_coding missense_variant MODERATE 1556C>A Ala519Asp
M0068792 AADJNCJI_00003 2852 4 Skin 0.80 protein_coding synonymous_variant LOW 1554C>T Gly518Gly
M0068793 AADJNCJI_00003 2873 4 Skin 0.80 protein_coding synonymous_variant LOW 1533T>C His511His
M0068794 AADJNCJI_00003 3680 4 Skin 0.80 protein_coding synonymous_variant LOW 726C>G Ala242Ala
M0068795 AADJNCJI_00003 3692 4 Skin 0.80 protein_coding synonymous_variant LOW 714G>C Val238Val
M0068796 AADJNCJI_00003 3693 4 Skin 0.80 protein_coding missense_variant MODERATE 713T>G Val238Gly
M0068797 AADJNCJI_00003 3719 4 Skin 0.80 protein_coding synonymous_variant LOW 687G>C Ala229Ala
M0068798 AADJNCJI_00004 4624 4 Skin 0.80 protein_coding synonymous_variant LOW 24A>G Glu8Glu
M0068799 AADJNCJI_00004 4634 4 Skin 0.80 protein_coding missense_variant MODERATE 34A>G Asn12Asp
M0068800 AADJNCJI_00004 4687 4 Skin 0.80 protein_coding synonymous_variant LOW 87G>C Pro29Pro
M0068801 AADJNCJI_00004 4991 3 Skin 0.60 protein_coding missense_variant MODERATE 391C>A Leu131Met
M0068802 AADJNCJI_00005 6814 3 Skin 0.60 protein_coding synonymous_variant LOW 699C>T Phe233Phe
M0068803 AADJNCJI_00005 6817 4 Skin 0.80 protein_coding synonymous_variant LOW 702A>C Ala234Ala
M0068804 AADJNCJI_00005 7204 4 Skin 0.80 protein_coding synonymous_variant LOW 1089G>C Ser363Ser
M0068805 AADJNCJI_00005 7303 4 Skin 0.80 protein_coding synonymous_variant LOW 1188C>T Asn396Asn
M0068806 AADJNCJI_00005 7339 4 Skin 0.80 protein_coding synonymous_variant LOW 1224C>T Ala408Ala
M0068807 AADJNCJI_00003 7631 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -3226G>T None
M0068808 AADJNCJI_00003 7636 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -3231T>C None
M0068809 AADJNCJI_00006 8225 3 Skin 0.60 protein_coding synonymous_variant LOW 465A>C Ala155Ala
M0068810 AADJNCJI_00003 8256 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -3851C>G None
M0068811 AADJNCJI_00007 8569 4 Skin 0.80 protein_coding synonymous_variant LOW 228G>A Gln76Gln
M0068812 AADJNCJI_00007 8572 4 Skin 0.80 protein_coding synonymous_variant LOW 231C>G Gly77Gly
M0068813 AADJNCJI_00007 8864 4 Skin 0.80 protein_coding missense_variant MODERATE 523G>C Gly175Arg
M0068814 AADJNCJI_00008 9227 3 Skin 0.60 protein_coding missense_variant MODERATE 275G>C Cys92Ser
M0068815 AADJNCJI_00008 9231 3 Skin 0.60 protein_coding synonymous_variant LOW 279A>G Gly93Gly
M0068816 AADJNCJI_00009 10120 3 Skin 0.60 protein_coding missense_variant MODERATE 425G>A Gly142Glu
M0068817 AADJNCJI_00001 769 3 Skin 0.60 protein_coding synonymous_variant LOW 243A>G Glu81Glu
M0068818 AADJNCJI_00001 782 3 Skin 0.60 protein_coding missense_variant MODERATE 230C>T Ala77Val
M0068819 AADJNCJI_00001 788 3 Skin 0.60 protein_coding missense_variant MODERATE 224C>T Pro75Leu
M0068820 AADJNCJI_00001 798 3 Skin 0.60 protein_coding missense_variant MODERATE 214C>G Pro72Ala
M0068821 AADJNCJI_00001 806 3 Skin 0.60 protein_coding missense_variant MODERATE 206A>T Gln69Leu
M0068822 AADJNCJI_00001 820 3 Skin 0.60 protein_coding synonymous_variant LOW 192C>T Phe64Phe
M0068823 AADJNCJI_00003 3512 3 Skin 0.60 protein_coding synonymous_variant LOW 894G>A Val298Val
M0068824 AADJNCJI_00003 3521 3 Skin 0.60 protein_coding synonymous_variant LOW 885C>T His295His
M0068825 AADJNCJI_00003 3708 3 Skin 0.60 protein_coding missense_variant MODERATE 698A>T Asp233Val
M0068826 AADJNCJI_00003 3716 3 Skin 0.60 protein_coding missense_variant MODERATE 690G>C Arg230Ser
M0068827 AADJNCJI_00003 3728 3 Skin 0.60 protein_coding synonymous_variant LOW 678C>T Asp226Asp
M0068828 AADJNCJI_00004 5878 3 Skin 0.60 protein_coding synonymous_variant LOW 1278T>C His426His
M0068829 AADJNCJI_00004 5890 3 Skin 0.60 protein_coding synonymous_variant LOW 1290C>T Asp430Asp
M0068830 AADJNCJI_00001 5919 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4908C>T None
M0068831 AADJNCJI_00005 6301 3 Skin 0.60 protein_coding synonymous_variant LOW 186T>G Arg62Arg
M0068832 AADJNCJI_00003 7688 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -3283A>G None
M0068833 AADJNCJI_00003 7724 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -3319C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term