Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2992
  Reference Plasmid   DSKIN0031-1_bin.8__k141_38602
  Reference Plasmid Size   11394
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0069322 MFEGCJEK_00003 2261 4 Skin 0.80 protein_coding synonymous_variant LOW 258T>C Asp86Asp
M0069323 MFEGCJEK_00003 2327 4 Skin 0.80 protein_coding synonymous_variant LOW 192G>A Gly64Gly
M0069324 MFEGCJEK_00004 2863 3 Skin 0.60 protein_coding synonymous_variant LOW 1102T>C Leu368Leu
M0069325 MFEGCJEK_00006 4942 3 Skin 0.60 protein_coding missense_variant MODERATE 874C>G Leu292Val
M0069326 MFEGCJEK_00006 5234 3 Skin 0.60 protein_coding synonymous_variant LOW 582A>C Pro194Pro
M0069327 MFEGCJEK_00006 5240 3 Skin 0.60 protein_coding synonymous_variant LOW 576C>T Gly192Gly
M0069328 MFEGCJEK_00006 5732 4 Skin 0.80 protein_coding synonymous_variant LOW 84C>G Thr28Thr
M0069329 MFEGCJEK_00003 2188 3 Skin 0.60 protein_coding synonymous_variant LOW 331T>C Leu111Leu
M0069330 MFEGCJEK_00003 2189 3 Skin 0.60 protein_coding synonymous_variant LOW 330A>G Glu110Glu
M0069331 MFEGCJEK_00003 2198 3 Skin 0.60 protein_coding synonymous_variant LOW 321C>T Gly107Gly
M0069332 MFEGCJEK_00003 2201 3 Skin 0.60 protein_coding synonymous_variant LOW 318C>G Thr106Thr
M0069333 MFEGCJEK_00003 2207 3 Skin 0.60 protein_coding synonymous_variant LOW 312T>C Ile104Ile
M0069334 MFEGCJEK_00003 2210 3 Skin 0.60 protein_coding synonymous_variant LOW 309A>G Glu103Glu
M0069335 MFEGCJEK_00003 2216 3 Skin 0.60 protein_coding synonymous_variant LOW 303C>G Pro101Pro
M0069336 MFEGCJEK_00003 2240 3 Skin 0.60 protein_coding synonymous_variant LOW 279T>C Arg93Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term