Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2993
  Reference Plasmid   DSKIN0031-1_bin.8__k141_5941
  Reference Plasmid Size   9597
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0069337 DHJGDEDB_00001 586 5 Skin 0.56 protein_coding synonymous_variant LOW 375T>C Gly125Gly
M0069338 DHJGDEDB_00001 955 4 Skin 0.44 protein_coding synonymous_variant LOW 744C>T Phe248Phe
M0069339 DHJGDEDB_00002 1133 6 Skin 0.67 protein_coding missense_variant MODERATE 11G>C Ser4Thr
M0069340 DHJGDEDB_00002 1134 5 Skin 0.56 protein_coding synonymous_variant LOW 12T>C Ser4Ser
M0069341 DHJGDEDB_00002 1139 3 Skin 0.33 protein_coding missense_variant MODERATE 17C>T Thr6Ile
M0069342 DHJGDEDB_00002 1199 3 Skin 0.33 protein_coding missense_variant MODERATE 77A>T Asp26Val
M0069343 DHJGDEDB_00003 1749 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -25T>C None
M0069344 DHJGDEDB_00003 1752 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -22G>C None
M0069345 DHJGDEDB_00001 817 5 Skin 0.56 protein_coding synonymous_variant LOW 606A>G Ala202Ala
M0069346 DHJGDEDB_00002 1533 4 Skin 0.44 protein_coding synonymous_variant LOW 411T>C Asp137Asp
M0069347 DHJGDEDB_00002 1726 6 Skin 0.67 protein_coding stop_lost&splice_region_variant HIGH 604T>A Ter202Lysext*?
M0069348 DHJGDEDB_00004 2273 3 Skin 0.33 protein_coding synonymous_variant LOW 336A>C Ile112Ile
M0069349 DHJGDEDB_00004 2459 6 Skin 0.67 protein_coding synonymous_variant LOW 522A>G Glu174Glu
M0069350 DHJGDEDB_00004 3403 5 Skin 0.56 protein_coding missense_variant MODERATE 1466T>C Leu489Pro
M0069351 DHJGDEDB_00005 4422 6 Skin 0.67 protein_coding missense_variant MODERATE 959T>C Val320Ala
M0069352 DHJGDEDB_00005 4437 6 Skin 0.67 protein_coding missense_variant MODERATE 974C>G Ala325Gly
M0069353 DHJGDEDB_00005 4632 4 Skin 0.44 protein_coding missense_variant MODERATE 1169T>C Val390Ala
M0069354 DHJGDEDB_00006 4806 3 Skin 0.33 protein_coding synonymous_variant LOW 75C>T Asp25Asp
M0069355 DHJGDEDB_00006 4810 3 Skin 0.33 protein_coding missense_variant MODERATE 79G>T Ala27Ser
M0069356 DHJGDEDB_00006 5178 3 Skin 0.33 protein_coding synonymous_variant LOW 447A>G Ala149Ala
M0069357 DHJGDEDB_00006 5181 3 Skin 0.33 protein_coding synonymous_variant LOW 450G>A Ala150Ala
M0069358 DHJGDEDB_00006 5199 3 Skin 0.33 protein_coding synonymous_variant LOW 468A>G Ser156Ser
M0069359 DHJGDEDB_00006 5217 3 Skin 0.33 protein_coding synonymous_variant LOW 486A>G Val162Val
M0069360 DHJGDEDB_00006 5439 6 Skin 0.67 protein_coding synonymous_variant LOW 708G>C Arg236Arg
M0069361 DHJGDEDB_00007 5692 3 Skin 0.33 protein_coding synonymous_variant LOW 222A>G Val74Val
M0069362 DHJGDEDB_00008 6329 3 Skin 0.33 protein_coding synonymous_variant LOW 51C>A Pro17Pro
M0069363 DHJGDEDB_00008 6347 4 Skin 0.44 protein_coding synonymous_variant LOW 69C>A Ala23Ala
M0069364 DHJGDEDB_00008 6549 7 Skin 0.78 protein_coding synonymous_variant LOW 271T>C Leu91Leu
M0069365 DHJGDEDB_00008 7064 4 Skin 0.44 protein_coding synonymous_variant LOW 786G>A Gln262Gln
M0069366 DHJGDEDB_00008 7082 5 Skin 0.56 protein_coding synonymous_variant LOW 804C>T Gly268Gly
M0069367 DHJGDEDB_00008 7085 4 Skin 0.44 protein_coding synonymous_variant LOW 807C>A Ala269Ala
M0069368 DHJGDEDB_00009 7253 4 Skin 0.44 protein_coding missense_variant MODERATE 71T>C Val24Ala
M0069369 DHJGDEDB_00009 7552 4 Skin 0.44 protein_coding missense_variant MODERATE 370T>A Phe124Ile
M0069370 DHJGDEDB_00010 8151 5 Skin 0.56 protein_coding missense_variant MODERATE 301G>A Ala101Thr
M0069371 DHJGDEDB_00010 8401 5 Skin 0.56 protein_coding missense_variant MODERATE 551G>A Arg184Gln
M0069372 DHJGDEDB_00010 8420 5 Skin 0.56 protein_coding synonymous_variant LOW 570T>C Ala190Ala
M0069373 DHJGDEDB_00004 3176 4 Skin 0.44 protein_coding synonymous_variant LOW 1239G>A Gln413Gln
M0069374 DHJGDEDB_00005 3918 4 Skin 0.44 protein_coding missense_variant MODERATE 455G>A Gly152Asp
M0069375 DHJGDEDB_00005 4300 3 Skin 0.33 protein_coding synonymous_variant LOW 837A>C Ala279Ala
M0069376 DHJGDEDB_00005 4313 3 Skin 0.33 protein_coding missense_variant MODERATE 850A>G Thr284Ala
M0069377 DHJGDEDB_00006 5037 4 Skin 0.44 protein_coding synonymous_variant LOW 306G>A Gln102Gln
M0069378 DHJGDEDB_00007 5495 6 Skin 0.67 protein_coding missense_variant MODERATE 25C>A Pro9Thr
M0069379 DHJGDEDB_00007 5514 6 Skin 0.67 protein_coding missense_variant MODERATE 44C>T Pro15Leu
M0069380 DHJGDEDB_00007 5614 3 Skin 0.33 protein_coding synonymous_variant LOW 144C>A Ala48Ala
M0069381 DHJGDEDB_00007 6121 4 Skin 0.44 protein_coding synonymous_variant LOW 651G>A Ser217Ser
M0069382 DHJGDEDB_00007 6145 4 Skin 0.44 protein_coding synonymous_variant LOW 675G>A Val225Val
M0069383 DHJGDEDB_00010 8120 3 Skin 0.33 protein_coding synonymous_variant LOW 270C>A Ala90Ala
M0069384 DHJGDEDB_00010 8879 3 Skin 0.33 protein_coding synonymous_variant LOW 1029G>A Ala343Ala
M0069385 DHJGDEDB_00004 2505 3 Skin 0.33 protein_coding missense_variant MODERATE 568G>A Asp190Asn
M0069386 DHJGDEDB_00007 5540 5 Skin 0.56 protein_coding missense_variant MODERATE 70G>T Ala24Ser
M0069387 DHJGDEDB_00010 8396 3 Skin 0.33 protein_coding synonymous_variant LOW 546G>A Ala182Ala
M0069388 DHJGDEDB_00010 8465 4 Skin 0.44 protein_coding synonymous_variant LOW 615G>A Glu205Glu
M0069389 DHJGDEDB_00010 8519 3 Skin 0.33 protein_coding synonymous_variant LOW 669C>G Ser223Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term