Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3004
  Reference Plasmid   DSKIN0033-1_bin.10__k141_9959
  Reference Plasmid Size   14896
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0069663 KOCKFEBA_00002 2041 3 Skin 0.60 protein_coding synonymous_variant LOW 978T>C Ala326Ala
M0069664 KOCKFEBA_00002 2050 3 Skin 0.60 protein_coding synonymous_variant LOW 987T>C Gly329Gly
M0069665 KOCKFEBA_00002 2056 3 Skin 0.60 protein_coding synonymous_variant LOW 993T>C Arg331Arg
M0069666 KOCKFEBA_00002 2075 3 Skin 0.60 protein_coding missense_variant MODERATE 1012G>T Ala338Ser
M0069667 KOCKFEBA_00002 2113 3 Skin 0.60 protein_coding synonymous_variant LOW 1050G>A Ser350Ser
M0069668 KOCKFEBA_00003 3469 4 Skin 0.80 protein_coding missense_variant MODERATE 53T>C Val18Ala
M0069669 KOCKFEBA_00003 3473 4 Skin 0.80 protein_coding synonymous_variant LOW 57G>T Leu19Leu
M0069670 KOCKFEBA_00003 3483 4 Skin 0.80 protein_coding missense_variant MODERATE 67G>A Ala23Thr
M0069671 KOCKFEBA_00003 3491 4 Skin 0.80 protein_coding synonymous_variant LOW 75G>A Ala25Ala
M0069672 KOCKFEBA_00003 3497 4 Skin 0.80 protein_coding synonymous_variant LOW 81A>C Ala27Ala
M0069673 KOCKFEBA_00003 3578 3 Skin 0.60 protein_coding synonymous_variant LOW 162G>A Ala54Ala
M0069674 KOCKFEBA_00003 3584 3 Skin 0.60 protein_coding synonymous_variant LOW 168T>C Ser56Ser
M0069675 KOCKFEBA_00003 3836 4 Skin 0.80 protein_coding synonymous_variant LOW 420T>C Arg140Arg
M0069676 KOCKFEBA_00003 3842 4 Skin 0.80 protein_coding synonymous_variant LOW 426T>C Asn142Asn
M0069677 KOCKFEBA_00004 5568 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -95A>C None
M0069678 KOCKFEBA_00004 6034 3 Skin 0.60 protein_coding synonymous_variant LOW 372A>G Leu124Leu
M0069679 KOCKFEBA_00004 6433 4 Skin 0.80 protein_coding synonymous_variant LOW 771G>C Val257Val
M0069680 KOCKFEBA_00005 7796 3 Skin 0.60 protein_coding synonymous_variant LOW 1209A>C Ala403Ala
M0069681 KOCKFEBA_00006 8980 3 Skin 0.60 protein_coding synonymous_variant LOW 930T>C Ile310Ile
M0069682 KOCKFEBA_00006 9136 3 Skin 0.60 protein_coding synonymous_variant LOW 774A>G Glu258Glu
M0069683 KOCKFEBA_00006 9202 3 Skin 0.60 protein_coding missense_variant MODERATE 708G>T Glu236Asp
M0069684 KOCKFEBA_00006 9244 3 Skin 0.60 protein_coding synonymous_variant LOW 666C>T Ala222Ala
M0069685 KOCKFEBA_00006 9544 3 Skin 0.60 protein_coding synonymous_variant LOW 366C>G Val122Val
M0069686 KOCKFEBA_00006 9562 3 Skin 0.60 protein_coding synonymous_variant LOW 348G>C Gly116Gly
M0069687 KOCKFEBA_00006 9565 3 Skin 0.60 protein_coding synonymous_variant LOW 345C>T Ile115Ile
M0069688 KOCKFEBA_00006 9588 3 Skin 0.60 protein_coding missense_variant MODERATE 322T>C Cys108Arg
M0069689 KOCKFEBA_00005 6777 3 Skin 0.60 protein_coding synonymous_variant LOW 190C>T Leu64Leu
M0069690 KOCKFEBA_00005 6794 3 Skin 0.60 protein_coding synonymous_variant LOW 207C>G Ala69Ala
M0069691 KOCKFEBA_00005 6872 3 Skin 0.60 protein_coding synonymous_variant LOW 285C>T Asp95Asp
M0069692 KOCKFEBA_00005 7271 3 Skin 0.60 protein_coding synonymous_variant LOW 684C>G Val228Val
M0069693 KOCKFEBA_00005 7592 3 Skin 0.60 protein_coding synonymous_variant LOW 1005A>G Gln335Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
KOCKFEBA_00009 2.A.14.1.1 74.2 2.9e-235 4 558 0.9911 0.9964 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.14 The Lactate Permease (LctP) Family