Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3022
  Reference Plasmid   DSKIN0041-1_bin.40__k141_115641
  Reference Plasmid Size   44286
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0069802 PIKNKECJ_00001 37 6 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -171G>A None
M0069803 PIKNKECJ_00001 42 6 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -166C>T None
M0069804 PIKNKECJ_00001 526 4 Skin 0.29 protein_coding missense_variant MODERATE 319C>T Leu107Phe
M0069805 PIKNKECJ_00001 556 4 Skin 0.29 protein_coding missense_variant MODERATE 349C>T His117Tyr
M0069806 PIKNKECJ_00001 988 6 Skin 0.43 protein_coding missense_variant MODERATE 781G>C Gly261Arg
M0069807 PIKNKECJ_00001 1467 4 Skin 0.29 protein_coding synonymous_variant LOW 1260C>T Gly420Gly
M0069808 PIKNKECJ_00001 1483 4 Skin 0.29 protein_coding missense_variant MODERATE 1276C>G Arg426Gly
M0069809 PIKNKECJ_00001 1518 4 Skin 0.29 protein_coding missense_variant MODERATE 1311G>C Gln437His
M0069810 PIKNKECJ_00001 1581 4 Skin 0.29 protein_coding stop_lost&splice_region_variant HIGH 1374A>G Ter458Trpext*?
M0069811 PIKNKECJ_00002 1597 4 Skin 0.29 protein_coding synonymous_variant LOW 453G>T Ala151Ala
M0069812 PIKNKECJ_00002 1979 6 Skin 0.43 protein_coding missense_variant MODERATE 71G>C Gly24Ala
M0069813 PIKNKECJ_00003 2714 3 Skin 0.21 protein_coding synonymous_variant LOW 1209G>A Thr403Thr
M0069814 PIKNKECJ_00003 2909 5 Skin 0.36 protein_coding synonymous_variant LOW 1014C>T Ser338Ser
M0069815 PIKNKECJ_00003 2950 5 Skin 0.36 protein_coding missense_variant MODERATE 973C>A Pro325Thr
M0069816 PIKNKECJ_00005 4289 6 Skin 0.43 protein_coding synonymous_variant LOW 306A>C Ile102Ile
M0069817 PIKNKECJ_00006 5535 6 Skin 0.43 protein_coding synonymous_variant LOW 738A>C Gly246Gly
M0069818 PIKNKECJ_00006 5850 6 Skin 0.43 protein_coding synonymous_variant LOW 1053A>G Val351Val
M0069819 PIKNKECJ_00006 6111 5 Skin 0.36 protein_coding synonymous_variant LOW 1314A>G Val438Val
M0069820 PIKNKECJ_00006 6183 6 Skin 0.43 protein_coding synonymous_variant LOW 1386G>A Gln462Gln
M0069821 PIKNKECJ_00006 6246 6 Skin 0.43 protein_coding synonymous_variant LOW 1449T>C Tyr483Tyr
M0069822 PIKNKECJ_00003 7485 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -3563T>C None
M0069823 PIKNKECJ_00003 7513 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -3591C>A None
M0069824 PIKNKECJ_00001 1093 4 Skin 0.29 protein_coding missense_variant MODERATE 886T>A Cys296Ser
M0069825 PIKNKECJ_00005 4444 3 Skin 0.21 protein_coding missense_variant MODERATE 151C>A Leu51Ile
M0069826 PIKNKECJ_00005 4502 4 Skin 0.29 protein_coding synonymous_variant LOW 93G>C Val31Val
M0069827 PIKNKECJ_00005 4517 4 Skin 0.29 protein_coding synonymous_variant LOW 78C>G Gly26Gly
M0069828 PIKNKECJ_00005 4520 4 Skin 0.29 protein_coding synonymous_variant LOW 75G>A Ala25Ala
M0069829 PIKNKECJ_00002 4665 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2616G>A None
M0069830 PIKNKECJ_00006 5975 3 Skin 0.21 protein_coding missense_variant MODERATE 1178G>A Ser393Asn
M0069831 PIKNKECJ_00006 6191 4 Skin 0.29 protein_coding missense_variant MODERATE 1394C>T Pro465Leu
M0069832 PIKNKECJ_00006 6606 4 Skin 0.29 protein_coding synonymous_variant LOW 1809A>C Ala603Ala
M0069833 PIKNKECJ_00006 6639 4 Skin 0.29 protein_coding synonymous_variant LOW 1842C>A Arg614Arg
M0069834 PIKNKECJ_00006 6654 4 Skin 0.29 protein_coding synonymous_variant LOW 1857T>C Ala619Ala
M0069835 PIKNKECJ_00006 6657 4 Skin 0.29 protein_coding synonymous_variant LOW 1860T>G Gly620Gly
M0069836 PIKNKECJ_00001 1478 3 Skin 0.21 protein_coding missense_variant MODERATE 1271G>A Gly424Asp
M0069837 PIKNKECJ_00006 6042 3 Skin 0.21 protein_coding synonymous_variant LOW 1245A>G Ala415Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term