Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3038
  Reference Plasmid   DSKIN0049-1_bin.26__k141_27218
  Reference Plasmid Size   18890
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070087 HIDPHNOG_00003 2488 3 Skin 0.38 protein_coding synonymous_variant LOW 336T>C Tyr112Tyr
M0070088 HIDPHNOG_00003 2491 3 Skin 0.38 protein_coding synonymous_variant LOW 333G>C Val111Val
M0070089 HIDPHNOG_00004 2861 4 Skin 0.50 protein_coding missense_variant MODERATE 616G>T Ala206Ser
M0070090 HIDPHNOG_00004 2907 5 Skin 0.63 protein_coding missense_variant MODERATE 570C>A Asp190Glu
M0070091 HIDPHNOG_00004 2972 5 Skin 0.63 protein_coding synonymous_variant LOW 505C>T Leu169Leu
M0070092 HIDPHNOG_00004 3123 5 Skin 0.63 protein_coding synonymous_variant LOW 354A>G Glu118Glu
M0070093 HIDPHNOG_00004 3175 4 Skin 0.50 protein_coding missense_variant MODERATE 302C>T Ala101Val
M0070094 HIDPHNOG_00004 3287 3 Skin 0.38 protein_coding missense_variant MODERATE 190G>C Glu64Gln
M0070095 HIDPHNOG_00004 3293 3 Skin 0.38 protein_coding missense_variant MODERATE 184G>A Gly62Ser
M0070096 HIDPHNOG_00004 3301 5 Skin 0.63 protein_coding missense_variant MODERATE 176C>A Pro59His
M0070097 HIDPHNOG_00004 3333 3 Skin 0.38 protein_coding synonymous_variant LOW 144C>T Ala48Ala
M0070098 HIDPHNOG_00004 3342 3 Skin 0.38 protein_coding synonymous_variant LOW 135T>C Ile45Ile
M0070099 HIDPHNOG_00005 3588 3 Skin 0.38 protein_coding synonymous_variant LOW 1740A>G Gln580Gln
M0070100 HIDPHNOG_00005 3612 3 Skin 0.38 protein_coding synonymous_variant LOW 1716T>C His572His
M0070101 HIDPHNOG_00005 3627 3 Skin 0.38 protein_coding synonymous_variant LOW 1701A>G Lys567Lys
M0070102 HIDPHNOG_00005 4356 5 Skin 0.63 protein_coding synonymous_variant LOW 972T>C Asn324Asn
M0070103 HIDPHNOG_00005 4383 5 Skin 0.63 protein_coding synonymous_variant LOW 945T>C Tyr315Tyr
M0070104 HIDPHNOG_00005 4389 5 Skin 0.63 protein_coding synonymous_variant LOW 939C>T Arg313Arg
M0070105 HIDPHNOG_00005 4407 5 Skin 0.63 protein_coding synonymous_variant LOW 921G>T Leu307Leu
M0070106 HIDPHNOG_00005 4409 5 Skin 0.63 protein_coding missense_variant MODERATE 919C>A Leu307Met
M0070107 HIDPHNOG_00005 4420 5 Skin 0.63 protein_coding missense_variant MODERATE 908A>G Asn303Ser
M0070108 HIDPHNOG_00005 4431 4 Skin 0.50 protein_coding synonymous_variant LOW 897C>T His299His
M0070109 HIDPHNOG_00005 4565 5 Skin 0.63 protein_coding missense_variant MODERATE 763T>A Ser255Thr
M0070110 HIDPHNOG_00005 4568 5 Skin 0.63 protein_coding missense_variant MODERATE 760A>T Asn254Tyr
M0070111 HIDPHNOG_00005 4582 5 Skin 0.63 protein_coding missense_variant MODERATE 746T>G Leu249Arg
M0070112 HIDPHNOG_00005 4899 5 Skin 0.63 protein_coding synonymous_variant LOW 429G>A Ser143Ser
M0070113 HIDPHNOG_00005 5085 3 Skin 0.38 protein_coding missense_variant MODERATE 243C>A Asp81Glu
M0070114 HIDPHNOG_00005 5136 3 Skin 0.38 protein_coding synonymous_variant LOW 192G>T Pro64Pro
M0070115 HIDPHNOG_00007 6789 3 Skin 0.38 protein_coding synonymous_variant LOW 150G>T Val50Val
M0070116 HIDPHNOG_00004 3384 3 Skin 0.38 protein_coding synonymous_variant LOW 93C>T Cys31Cys
M0070117 HIDPHNOG_00004 3396 3 Skin 0.38 protein_coding synonymous_variant LOW 81G>C Ala27Ala
M0070118 HIDPHNOG_00004 3401 3 Skin 0.38 protein_coding missense_variant MODERATE 76C>G Gln26Glu
M0070119 HIDPHNOG_00004 3435 3 Skin 0.38 protein_coding synonymous_variant LOW 42G>A Lys14Lys
M0070120 HIDPHNOG_00002 5540 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -3985G>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
HIDPHNOG_00014 ARO:3005323 72.5 3.4e-131 26 269 0.9037 0.9104 penicillin beta-lactam OXA beta-lactamase antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term