Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3040
  Reference Plasmid   DSKIN0049-1_bin.26__k141_40024
  Reference Plasmid Size   20381
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070185 FDKFKBOO_00011 12649 5 Skin 0.42 protein_coding missense_variant MODERATE 283G>T Ala95Ser
M0070186 FDKFKBOO_00012 13448 3 Skin 0.25 protein_coding missense_variant MODERATE 611A>C Lys204Thr
M0070187 FDKFKBOO_00012 13449 3 Skin 0.25 protein_coding missense_variant MODERATE 610A>G Lys204Glu
M0070188 FDKFKBOO_00012 13450 3 Skin 0.25 protein_coding synonymous_variant LOW 609C>T Arg203Arg
M0070189 FDKFKBOO_00012 13453 3 Skin 0.25 protein_coding synonymous_variant LOW 606G>C Gly202Gly
M0070190 FDKFKBOO_00012 13456 3 Skin 0.25 protein_coding synonymous_variant LOW 603A>G Glu201Glu
M0070191 FDKFKBOO_00012 13462 3 Skin 0.25 protein_coding synonymous_variant LOW 597C>G Ala199Ala
M0070192 FDKFKBOO_00012 13549 6 Skin 0.50 protein_coding synonymous_variant LOW 510G>C Leu170Leu
M0070193 FDKFKBOO_00012 13592 7 Skin 0.58 protein_coding missense_variant MODERATE 467A>G Asn156Ser
M0070194 FDKFKBOO_00012 13888 7 Skin 0.58 protein_coding synonymous_variant LOW 171G>C Thr57Thr
M0070195 FDKFKBOO_00013 14594 3 Skin 0.25 protein_coding synonymous_variant LOW 492T>G Ser164Ser
M0070196 FDKFKBOO_00013 14600 3 Skin 0.25 protein_coding synonymous_variant LOW 486G>A Glu162Glu
M0070197 FDKFKBOO_00013 14603 3 Skin 0.25 protein_coding synonymous_variant LOW 483A>C Gly161Gly
M0070198 FDKFKBOO_00013 14606 3 Skin 0.25 protein_coding synonymous_variant LOW 480C>G Pro160Pro
M0070199 FDKFKBOO_00013 14921 3 Skin 0.25 protein_coding synonymous_variant LOW 165T>A Ile55Ile
M0070200 FDKFKBOO_00013 15030 6 Skin 0.50 protein_coding missense_variant MODERATE 56T>C Val19Ala
M0070201 FDKFKBOO_00013 15032 6 Skin 0.50 protein_coding synonymous_variant LOW 54C>G Ala18Ala
M0070202 FDKFKBOO_00013 15033 6 Skin 0.50 protein_coding missense_variant MODERATE 53C>T Ala18Val
M0070203 FDKFKBOO_00013 15035 6 Skin 0.50 protein_coding synonymous_variant LOW 51T>G Val17Val
M0070204 FDKFKBOO_00013 15062 6 Skin 0.50 protein_coding synonymous_variant LOW 24C>A Thr8Thr
M0070205 FDKFKBOO_00013 15065 6 Skin 0.50 protein_coding missense_variant MODERATE 21C>G His7Gln
M0070206 FDKFKBOO_00014 15094 5 Skin 0.42 protein_coding synonymous_variant LOW 996A>G Arg332Arg
M0070207 FDKFKBOO_00014 15616 6 Skin 0.50 protein_coding synonymous_variant LOW 474G>C Val158Val
M0070208 FDKFKBOO_00014 15622 6 Skin 0.50 protein_coding synonymous_variant LOW 468C>T Pro156Pro
M0070209 FDKFKBOO_00014 15964 4 Skin 0.33 protein_coding synonymous_variant LOW 126G>A Gln42Gln
M0070210 FDKFKBOO_00015 16165 3 Skin 0.25 protein_coding missense_variant MODERATE 1733A>G His578Arg
M0070211 FDKFKBOO_00015 16197 3 Skin 0.25 protein_coding synonymous_variant LOW 1701A>G Gln567Gln
M0070212 FDKFKBOO_00015 16206 3 Skin 0.25 protein_coding synonymous_variant LOW 1692G>A Ala564Ala
M0070213 FDKFKBOO_00015 16212 3 Skin 0.25 protein_coding synonymous_variant LOW 1686G>A Gln562Gln
M0070214 FDKFKBOO_00015 16224 3 Skin 0.25 protein_coding synonymous_variant LOW 1674T>C Gly558Gly
M0070215 FDKFKBOO_00015 16398 8 Skin 0.67 protein_coding synonymous_variant LOW 1500A>C Leu500Leu
M0070216 FDKFKBOO_00011 11501 5 Skin 0.42 protein_coding synonymous_variant LOW 1431C>A Ala477Ala
M0070217 FDKFKBOO_00011 12341 3 Skin 0.25 protein_coding synonymous_variant LOW 591C>T Phe197Phe
M0070218 FDKFKBOO_00011 12476 3 Skin 0.25 protein_coding synonymous_variant LOW 456C>G Ala152Ala
M0070219 FDKFKBOO_00011 12726 4 Skin 0.33 protein_coding missense_variant MODERATE 206G>C Gly69Ala
M0070220 FDKFKBOO_00008 12989 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4713C>T None
M0070221 FDKFKBOO_00008 12992 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4716T>G None
M0070222 FDKFKBOO_00008 12994 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4718G>T None
M0070223 FDKFKBOO_00012 13660 5 Skin 0.42 protein_coding synonymous_variant LOW 399A>C Ile133Ile
M0070224 FDKFKBOO_00013 14132 4 Skin 0.33 protein_coding synonymous_variant LOW 954G>C Gly318Gly
M0070225 FDKFKBOO_00013 14174 6 Skin 0.50 protein_coding synonymous_variant LOW 912A>G Val304Val
M0070226 FDKFKBOO_00011 11804 3 Skin 0.25 protein_coding synonymous_variant LOW 1128T>C Asp376Asp
M0070227 FDKFKBOO_00011 11855 3 Skin 0.25 protein_coding synonymous_variant LOW 1077T>C His359His
M0070228 FDKFKBOO_00011 12161 3 Skin 0.25 protein_coding synonymous_variant LOW 771G>C Thr257Thr
M0070229 FDKFKBOO_00011 12164 3 Skin 0.25 protein_coding synonymous_variant LOW 768C>G Val256Val
M0070230 FDKFKBOO_00011 12173 3 Skin 0.25 protein_coding synonymous_variant LOW 759C>T Ile253Ile
M0070231 FDKFKBOO_00011 12377 3 Skin 0.25 protein_coding synonymous_variant LOW 555A>G Thr185Thr
M0070232 FDKFKBOO_00015 16389 4 Skin 0.33 protein_coding synonymous_variant LOW 1509T>C Asp503Asp
M0070233 FDKFKBOO_00015 16394 4 Skin 0.33 protein_coding missense_variant MODERATE 1504G>A Val502Ile
M0070234 FDKFKBOO_00015 16400 4 Skin 0.33 protein_coding synonymous_variant LOW 1498C>T Leu500Leu
M0070235 FDKFKBOO_00015 16401 4 Skin 0.33 protein_coding synonymous_variant LOW 1497C>T Ile499Ile
M0070236 FDKFKBOO_00015 16755 4 Skin 0.33 protein_coding synonymous_variant LOW 1143A>G Lys381Lys
M0070237 FDKFKBOO_00015 16773 4 Skin 0.33 protein_coding synonymous_variant LOW 1125C>G Gly375Gly
M0070238 FDKFKBOO_00015 17195 4 Skin 0.33 protein_coding synonymous_variant LOW 703C>T Leu235Leu
M0070239 FDKFKBOO_00015 17199 4 Skin 0.33 protein_coding synonymous_variant LOW 699T>C Ile233Ile
M0070240 FDKFKBOO_00015 17205 4 Skin 0.33 protein_coding synonymous_variant LOW 693G>A Gln231Gln
M0070241 FDKFKBOO_00015 17235 4 Skin 0.33 protein_coding synonymous_variant LOW 663A>C Ala221Ala
M0070242 FDKFKBOO_00015 17375 4 Skin 0.33 protein_coding missense_variant MODERATE 523C>T His175Tyr
M0070243 FDKFKBOO_00006 4706 4 Skin 0.33 protein_coding synonymous_variant LOW 498G>T Pro166Pro
M0070244 FDKFKBOO_00009 8706 3 Skin 0.25 protein_coding synonymous_variant LOW 1200G>A Glu400Glu
M0070245 FDKFKBOO_00009 8709 3 Skin 0.25 protein_coding synonymous_variant LOW 1197T>C Arg399Arg
M0070246 FDKFKBOO_00009 8822 3 Skin 0.25 protein_coding synonymous_variant LOW 1084T>C Leu362Leu
M0070247 FDKFKBOO_00009 8892 4 Skin 0.33 protein_coding synonymous_variant LOW 1014T>C Leu338Leu
M0070248 FDKFKBOO_00009 8949 5 Skin 0.42 protein_coding synonymous_variant LOW 957C>A Ala319Ala
M0070249 FDKFKBOO_00009 8952 5 Skin 0.42 protein_coding synonymous_variant LOW 954C>G Val318Val
M0070250 FDKFKBOO_00011 11294 4 Skin 0.33 protein_coding synonymous_variant LOW 1638C>G Ala546Ala
M0070251 FDKFKBOO_00012 13909 4 Skin 0.33 protein_coding synonymous_variant LOW 150C>G Thr50Thr
M0070252 FDKFKBOO_00012 13919 4 Skin 0.33 protein_coding missense_variant MODERATE 140A>C Lys47Thr
M0070253 FDKFKBOO_00012 13960 4 Skin 0.33 protein_coding synonymous_variant LOW 99C>A Thr33Thr
M0070254 FDKFKBOO_00012 13962 4 Skin 0.33 protein_coding missense_variant MODERATE 97A>G Thr33Ala
M0070255 FDKFKBOO_00012 13965 4 Skin 0.33 protein_coding missense_variant MODERATE 94A>T Thr32Ser
M0070256 FDKFKBOO_00012 13966 4 Skin 0.33 protein_coding synonymous_variant LOW 93C>G Pro31Pro
M0070257 FDKFKBOO_00012 13969 4 Skin 0.33 protein_coding synonymous_variant LOW 90A>C Thr30Thr
M0070258 FDKFKBOO_00012 13970 4 Skin 0.33 protein_coding missense_variant MODERATE 89C>A Thr30Lys
M0070259 FDKFKBOO_00005 4179 3 Skin 0.25 protein_coding synonymous_variant LOW 699C>T Ala233Ala
M0070260 FDKFKBOO_00006 4264 3 Skin 0.25 protein_coding missense_variant MODERATE 56G>A Gly19Asp
M0070261 FDKFKBOO_00008 8209 3 Skin 0.25 protein_coding missense_variant MODERATE 68A>G Gln23Arg
M0070262 FDKFKBOO_00015 17585 4 Skin 0.33 protein_coding missense_variant MODERATE 313C>A Pro105Thr
M0070263 FDKFKBOO_00016 18107 3 Skin 0.25 protein_coding synonymous_variant LOW 1599G>C Thr533Thr
M0070264 FDKFKBOO_00016 18279 4 Skin 0.33 protein_coding missense_variant MODERATE 1427G>T Gly476Val
M0070265 FDKFKBOO_00016 18451 3 Skin 0.25 protein_coding synonymous_variant LOW 1255T>C Leu419Leu
M0070266 FDKFKBOO_00016 18456 3 Skin 0.25 protein_coding missense_variant MODERATE 1250T>G Leu417Arg
M0070267 FDKFKBOO_00016 18466 3 Skin 0.25 protein_coding missense_variant MODERATE 1240A>G Ile414Val
M0070268 FDKFKBOO_00016 18499 3 Skin 0.25 protein_coding missense_variant MODERATE 1207T>C Cys403Arg
M0070269 FDKFKBOO_00016 19061 4 Skin 0.33 protein_coding synonymous_variant LOW 645T>C Gly215Gly
M0070270 FDKFKBOO_00016 19070 4 Skin 0.33 protein_coding synonymous_variant LOW 636T>C Phe212Phe
M0070271 FDKFKBOO_00016 19133 3 Skin 0.25 protein_coding synonymous_variant LOW 573C>T Ser191Ser
M0070272 FDKFKBOO_00016 19148 3 Skin 0.25 protein_coding synonymous_variant LOW 558C>T His186His
M0070273 FDKFKBOO_00016 19514 5 Skin 0.42 protein_coding synonymous_variant LOW 192A>C Ala64Ala
M0070274 FDKFKBOO_00016 19556 5 Skin 0.42 protein_coding synonymous_variant LOW 150T>C His50His
M0070275 FDKFKBOO_00016 19562 5 Skin 0.42 protein_coding synonymous_variant LOW 144C>T Ile48Ile
M0070276 FDKFKBOO_00016 19568 5 Skin 0.42 protein_coding synonymous_variant LOW 138C>G Ala46Ala
M0070277 FDKFKBOO_00016 19681 4 Skin 0.33 protein_coding missense_variant MODERATE 25C>G Pro9Ala
M0070278 FDKFKBOO_00016 19691 4 Skin 0.33 protein_coding missense_variant MODERATE 15T>G Asp5Glu
M0070279 FDKFKBOO_00016 19696 4 Skin 0.33 protein_coding missense_variant MODERATE 10A>C Thr4Pro
M0070280 FDKFKBOO_00016 19697 4 Skin 0.33 protein_coding synonymous_variant LOW 9C>A Ser3Ser
M0070281 FDKFKBOO_00013 19709 4 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4624T>A None
M0070282 FDKFKBOO_00013 19711 4 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4626A>G None
M0070283 FDKFKBOO_00013 19816 5 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -4731G>T None
M0070284 FDKFKBOO_00017 20018 3 Skin 0.25 protein_coding synonymous_variant LOW 291G>A Thr97Thr
M0070285 FDKFKBOO_00009 9675 3 Skin 0.25 protein_coding synonymous_variant LOW 231C>T Ile77Ile
M0070286 FDKFKBOO_00011 11231 3 Skin 0.25 protein_coding synonymous_variant LOW 1701T>C Phe567Phe
M0070287 FDKFKBOO_00011 11234 3 Skin 0.25 protein_coding synonymous_variant LOW 1698T>C Ser566Ser
M0070288 FDKFKBOO_00016 19352 3 Skin 0.25 protein_coding synonymous_variant LOW 354T>C Phe118Phe
M0070289 FDKFKBOO_00016 19370 3 Skin 0.25 protein_coding synonymous_variant LOW 336C>T Arg112Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
FDKFKBOO_00014 VFG037414 Acinetobactin 70.6 7.9e-117 23 321 0.8952 0.9708 Nutritional/Metabolic factor ferric siderophore ABC transporter, permease protein BauD experiment
FDKFKBOO_00014 VFG044227 Pseudomonine 74.8 1e-123 15 334 0.9581 1.0159 Nutritional/Metabolic factor iron chelate uptake ABC transporter family permease subunit prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term