Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3052
  Reference Plasmid   DSKIN0147-1_bin.9__k141_16319
  Reference Plasmid Size   17062
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070366 GMFJFFOA_00004 4240 3 Skin 0.60 protein_coding missense_variant MODERATE 277T>C Ser93Pro
M0070367 GMFJFFOA_00004 4298 3 Skin 0.60 protein_coding synonymous_variant LOW 219T>C Gly73Gly
M0070368 GMFJFFOA_00005 5098 3 Skin 0.60 protein_coding missense_variant MODERATE 398C>G Ala133Gly
M0070369 GMFJFFOA_00005 5103 3 Skin 0.60 protein_coding synonymous_variant LOW 393A>G Glu131Glu
M0070370 GMFJFFOA_00005 5380 3 Skin 0.60 protein_coding missense_variant MODERATE 116G>A Gly39Asp
M0070371 GMFJFFOA_00006 6179 3 Skin 0.60 protein_coding synonymous_variant LOW 180T>G Leu60Leu
M0070372 GMFJFFOA_00010 8599 3 Skin 0.60 protein_coding synonymous_variant LOW 630G>A Thr210Thr
M0070373 GMFJFFOA_00010 8643 4 Skin 0.80 protein_coding missense_variant MODERATE 674C>G Pro225Arg
M0070374 GMFJFFOA_00010 8650 4 Skin 0.80 protein_coding synonymous_variant LOW 681G>A Ala227Ala
M0070375 GMFJFFOA_00010 8668 4 Skin 0.80 protein_coding synonymous_variant LOW 699C>G Pro233Pro
M0070376 GMFJFFOA_00004 8933 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4417T>G None
M0070377 GMFJFFOA_00004 8952 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4436G>A None
M0070378 GMFJFFOA_00004 8956 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4440A>C None
M0070379 GMFJFFOA_00011 9212 3 Skin 0.60 protein_coding synonymous_variant LOW 219A>G Glu73Glu
M0070380 GMFJFFOA_00011 9227 3 Skin 0.60 protein_coding synonymous_variant LOW 234C>T Asp78Asp
M0070381 GMFJFFOA_00011 9233 3 Skin 0.60 protein_coding synonymous_variant LOW 240C>T Asp80Asp
M0070382 GMFJFFOA_00012 9819 3 Skin 0.60 protein_coding synonymous_variant LOW 276A>C Thr92Thr
M0070383 GMFJFFOA_00012 9852 3 Skin 0.60 protein_coding synonymous_variant LOW 309C>T Asn103Asn
M0070384 GMFJFFOA_00012 9853 3 Skin 0.60 protein_coding synonymous_variant LOW 310C>T Leu104Leu
M0070385 GMFJFFOA_00012 10191 3 Skin 0.60 protein_coding synonymous_variant LOW 648A>G Leu216Leu
M0070386 GMFJFFOA_00010 8482 3 Skin 0.60 protein_coding synonymous_variant LOW 513A>C Ile171Ile
M0070387 GMFJFFOA_00010 8488 3 Skin 0.60 protein_coding synonymous_variant LOW 519A>G Lys173Lys
M0070388 GMFJFFOA_00010 8503 3 Skin 0.60 protein_coding synonymous_variant LOW 534G>C Val178Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GMFJFFOA_00003 2.A.1.45.2 79.6 2.8e-201 1 427 0.9727 0.9682 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)