Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3057
  Reference Plasmid   DSKIN0147-1_bin.9__k141_8009
  Reference Plasmid Size   38060
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070519 CLDPGOLC_00013 15000 3 Skin 0.18 protein_coding synonymous_variant LOW 606G>A Gln202Gln
M0070520 CLDPGOLC_00013 15039 3 Skin 0.18 protein_coding synonymous_variant LOW 645A>G Gln215Gln
M0070521 CLDPGOLC_00013 15040 3 Skin 0.18 protein_coding synonymous_variant LOW 646T>C Leu216Leu
M0070522 CLDPGOLC_00013 15045 3 Skin 0.18 protein_coding synonymous_variant LOW 651C>T Ile217Ile
M0070523 CLDPGOLC_00013 15083 3 Skin 0.18 protein_coding missense_variant MODERATE 689G>A Gly230Asp
M0070524 CLDPGOLC_00013 15126 3 Skin 0.18 protein_coding missense_variant MODERATE 732C>G His244Gln
M0070525 CLDPGOLC_00013 15222 6 Skin 0.35 protein_coding synonymous_variant LOW 828C>G Val276Val
M0070526 CLDPGOLC_00014 15619 6 Skin 0.35 protein_coding synonymous_variant LOW 9T>C Tyr3Tyr
M0070527 CLDPGOLC_00015 16015 5 Skin 0.29 protein_coding synonymous_variant LOW 84C>T Ala28Ala
M0070528 CLDPGOLC_00015 16356 4 Skin 0.24 protein_coding missense_variant MODERATE 425G>A Ser142Asn
M0070529 CLDPGOLC_00015 16453 3 Skin 0.18 protein_coding synonymous_variant LOW 522A>G Ala174Ala
M0070530 CLDPGOLC_00015 16774 4 Skin 0.24 protein_coding synonymous_variant LOW 843A>C Ala281Ala
M0070531 CLDPGOLC_00015 16792 4 Skin 0.24 protein_coding synonymous_variant LOW 861T>C Asp287Asp
M0070532 CLDPGOLC_00015 16857 3 Skin 0.18 protein_coding missense_variant MODERATE 926G>A Arg309Lys
M0070533 CLDPGOLC_00016 17407 3 Skin 0.18 protein_coding missense_variant MODERATE 436A>C Ile146Leu
M0070534 CLDPGOLC_00016 17560 3 Skin 0.18 protein_coding missense_variant MODERATE 589G>A Asp197Asn
M0070535 CLDPGOLC_00017 17931 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -68A>C None
M0070536 CLDPGOLC_00017 17984 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -15C>T None
M0070537 CLDPGOLC_00017 17994 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -5G>A None
M0070538 CLDPGOLC_00017 18328 3 Skin 0.18 protein_coding synonymous_variant LOW 330A>G Arg110Arg
M0070539 CLDPGOLC_00017 18745 3 Skin 0.18 protein_coding synonymous_variant LOW 747G>C Gly249Gly
M0070540 CLDPGOLC_00028 30469 3 Skin 0.18 protein_coding synonymous_variant LOW 2622C>G Ala874Ala
M0070541 CLDPGOLC_00028 30635 3 Skin 0.18 protein_coding missense_variant MODERATE 2456C>G Ala819Gly
M0070542 CLDPGOLC_00028 30639 3 Skin 0.18 protein_coding missense_variant MODERATE 2452C>G Pro818Ala
M0070543 CLDPGOLC_00028 30640 3 Skin 0.18 protein_coding synonymous_variant LOW 2451A>G Ala817Ala
M0070544 CLDPGOLC_00028 30790 3 Skin 0.18 protein_coding synonymous_variant LOW 2301G>A Glu767Glu
M0070545 CLDPGOLC_00028 30793 3 Skin 0.18 protein_coding synonymous_variant LOW 2298G>C Ala766Ala
M0070546 CLDPGOLC_00028 30862 3 Skin 0.18 protein_coding synonymous_variant LOW 2229C>G Arg743Arg
M0070547 CLDPGOLC_00028 30886 3 Skin 0.18 protein_coding synonymous_variant LOW 2205C>T Pro735Pro
M0070548 CLDPGOLC_00028 30901 3 Skin 0.18 protein_coding synonymous_variant LOW 2190G>C Pro730Pro
M0070549 CLDPGOLC_00028 31006 3 Skin 0.18 protein_coding synonymous_variant LOW 2085T>C Ser695Ser
M0070550 CLDPGOLC_00028 31589 3 Skin 0.18 protein_coding missense_variant MODERATE 1502G>T Arg501Leu
M0070551 CLDPGOLC_00028 32779 3 Skin 0.18 protein_coding synonymous_variant LOW 312G>C Gly104Gly
M0070552 CLDPGOLC_00001 310 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -114C>A None
M0070553 CLDPGOLC_00001 414 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -10T>C None
M0070554 CLDPGOLC_00001 930 6 Skin 0.35 protein_coding synonymous_variant LOW 507T>C Asp169Asp
M0070555 CLDPGOLC_00001 969 6 Skin 0.35 protein_coding synonymous_variant LOW 546A>G Glu182Glu
M0070556 CLDPGOLC_00001 1010 6 Skin 0.35 protein_coding missense_variant MODERATE 587C>G Ala196Gly
M0070557 CLDPGOLC_00001 1020 6 Skin 0.35 protein_coding synonymous_variant LOW 597A>G Ser199Ser
M0070558 CLDPGOLC_00001 1021 6 Skin 0.35 protein_coding missense_variant MODERATE 598T>G Leu200Val
M0070559 CLDPGOLC_00001 1041 6 Skin 0.35 protein_coding synonymous_variant LOW 618T>G Val206Val
M0070560 CLDPGOLC_00001 1209 5 Skin 0.29 protein_coding missense_variant MODERATE 786G>C Gln262His
M0070561 CLDPGOLC_00001 1260 6 Skin 0.35 protein_coding synonymous_variant LOW 837C>G Arg279Arg
M0070562 CLDPGOLC_00002 1884 6 Skin 0.35 protein_coding synonymous_variant LOW 213G>C Gly71Gly
M0070563 CLDPGOLC_00002 2169 6 Skin 0.35 protein_coding synonymous_variant LOW 498T>C Arg166Arg
M0070564 CLDPGOLC_00002 2275 5 Skin 0.29 protein_coding synonymous_variant LOW 604T>C Leu202Leu
M0070565 CLDPGOLC_00002 2517 4 Skin 0.24 protein_coding synonymous_variant LOW 846A>G Glu282Glu
M0070566 CLDPGOLC_00002 2562 5 Skin 0.29 protein_coding synonymous_variant LOW 891C>A Pro297Pro
M0070567 CLDPGOLC_00002 2820 3 Skin 0.18 protein_coding synonymous_variant LOW 1149A>G Thr383Thr
M0070568 CLDPGOLC_00002 3801 3 Skin 0.18 protein_coding synonymous_variant LOW 2130A>G Ala710Ala
M0070569 CLDPGOLC_00003 3850 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -91A>C None
M0070570 CLDPGOLC_00003 4537 3 Skin 0.18 protein_coding synonymous_variant LOW 597G>C Thr199Thr
M0070571 CLDPGOLC_00005 5857 3 Skin 0.18 protein_coding synonymous_variant LOW 258G>C Ala86Ala
M0070572 CLDPGOLC_00005 6833 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -719C>T None
M0070573 CLDPGOLC_00001 1088 5 Skin 0.29 protein_coding stop_gained HIGH 665G>A Trp222*
M0070574 CLDPGOLC_00001 1089 5 Skin 0.29 protein_coding missense_variant MODERATE 666G>C Trp222Cys
M0070575 CLDPGOLC_00001 1097 5 Skin 0.29 protein_coding missense_variant MODERATE 674A>C Asn225Thr
M0070576 CLDPGOLC_00002 2214 4 Skin 0.24 protein_coding synonymous_variant LOW 543T>C Gly181Gly
M0070577 CLDPGOLC_00002 2379 3 Skin 0.18 protein_coding synonymous_variant LOW 708T>C Asn236Asn
M0070578 CLDPGOLC_00002 2757 4 Skin 0.24 protein_coding synonymous_variant LOW 1086C>G Thr362Thr
M0070579 CLDPGOLC_00012 12302 3 Skin 0.18 protein_coding synonymous_variant LOW 474G>A Val158Val
M0070580 CLDPGOLC_00012 12344 3 Skin 0.18 protein_coding synonymous_variant LOW 516C>G Val172Val
M0070581 CLDPGOLC_00012 12456 3 Skin 0.18 protein_coding synonymous_variant LOW 628C>T Leu210Leu
M0070582 CLDPGOLC_00012 12932 3 Skin 0.18 protein_coding synonymous_variant LOW 1104T>C Ala368Ala
M0070583 CLDPGOLC_00012 13082 3 Skin 0.18 protein_coding synonymous_variant LOW 1254T>G Ser418Ser
M0070584 CLDPGOLC_00012 13448 3 Skin 0.18 protein_coding synonymous_variant LOW 1620C>T Asp540Asp
M0070585 CLDPGOLC_00012 13938 3 Skin 0.18 protein_coding missense_variant MODERATE 2110T>G Ser704Ala
M0070586 CLDPGOLC_00012 13940 3 Skin 0.18 protein_coding synonymous_variant LOW 2112A>C Ser704Ser
M0070587 CLDPGOLC_00012 13949 3 Skin 0.18 protein_coding synonymous_variant LOW 2121A>G Val707Val
M0070588 CLDPGOLC_00001 198 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -226C>T None
M0070589 CLDPGOLC_00002 1628 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -44T>C None
M0070590 CLDPGOLC_00002 1653 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -19C>G None
M0070591 CLDPGOLC_00012 13784 3 Skin 0.18 protein_coding synonymous_variant LOW 1956G>A Glu652Glu
M0070592 CLDPGOLC_00012 13793 3 Skin 0.18 protein_coding synonymous_variant LOW 1965C>A Gly655Gly
M0070593 CLDPGOLC_00012 13802 3 Skin 0.18 protein_coding synonymous_variant LOW 1974A>G Ser658Ser
M0070594 CLDPGOLC_00012 13803 3 Skin 0.18 protein_coding missense_variant MODERATE 1975T>C Ser659Pro
M0070595 CLDPGOLC_00013 14234 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -161A>C None
M0070596 CLDPGOLC_00013 14238 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -157C>G None
M0070597 CLDPGOLC_00013 14259 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -136C>A None
M0070598 CLDPGOLC_00013 14260 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -135G>T None
M0070599 CLDPGOLC_00013 14289 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -106C>T None
M0070600 CLDPGOLC_00013 14305 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -90G>A None
M0070601 CLDPGOLC_00013 14378 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -17A>G None
M0070602 CLDPGOLC_00013 14384 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -11A>C None
M0070603 CLDPGOLC_00013 14385 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -10C>A None
M0070604 CLDPGOLC_00013 14409 3 Skin 0.18 protein_coding synonymous_variant LOW 15C>T Phe5Phe
M0070605 CLDPGOLC_00013 14931 3 Skin 0.18 protein_coding synonymous_variant LOW 537C>T Asp179Asp
M0070606 CLDPGOLC_00013 14955 3 Skin 0.18 protein_coding synonymous_variant LOW 561G>A Ala187Ala
M0070607 CLDPGOLC_00013 15498 3 Skin 0.18 protein_coding synonymous_variant LOW 1104A>G Gln368Gln
M0070608 CLDPGOLC_00017 18664 3 Skin 0.18 protein_coding synonymous_variant LOW 666C>G Ser222Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term