Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3059
  Reference Plasmid   DSKIN0152-1_bin.3__k141_26273
  Reference Plasmid Size   8104
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070631 DNNHPPPD_00002 2014 3 Skin 0.60 protein_coding missense_variant MODERATE 421A>G Ile141Val
M0070632 DNNHPPPD_00002 2067 3 Skin 0.60 protein_coding missense_variant MODERATE 474G>T Trp158Cys
M0070633 DNNHPPPD_00002 2091 3 Skin 0.60 protein_coding synonymous_variant LOW 498G>A Ala166Ala
M0070634 DNNHPPPD_00002 2097 3 Skin 0.60 protein_coding synonymous_variant LOW 504G>A Thr168Thr
M0070635 DNNHPPPD_00002 2125 3 Skin 0.60 protein_coding synonymous_variant LOW 532C>T Leu178Leu
M0070636 DNNHPPPD_00002 2143 3 Skin 0.60 protein_coding missense_variant MODERATE 550G>A Val184Ile
M0070637 DNNHPPPD_00003 2902 4 Skin 0.80 protein_coding synonymous_variant LOW 51C>G Gly17Gly
M0070638 DNNHPPPD_00003 2906 4 Skin 0.80 protein_coding missense_variant MODERATE 55C>T Pro19Ser
M0070639 DNNHPPPD_00003 2938 3 Skin 0.60 protein_coding synonymous_variant LOW 87C>T Asn29Asn
M0070640 DNNHPPPD_00003 2950 3 Skin 0.60 protein_coding synonymous_variant LOW 99T>C Gly33Gly
M0070641 DNNHPPPD_00006 5014 3 Skin 0.60 protein_coding missense_variant MODERATE 314T>C Val105Ala
M0070642 DNNHPPPD_00003 3277 3 Skin 0.60 protein_coding synonymous_variant LOW 426T>A Ala142Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
DNNHPPPD_00002 Chromium (Cr) 70.3 5.1e-150 3 395 0.9899 0.9825 experiment
DNNHPPPD_00004 Chromium (Cr), Methyl Viologen [class: Paraquat], Menadione [class: Naphthoquinone] 83.3 2e-75 1 150 0.9868 1.0000 experiment
DNNHPPPD_00003 Chromium (Cr) 99.7 9.3e-174 1 302 1.0000 1.0000 prediction
DNNHPPPD_00004 Chromium (Cr) 100 5.1e-88 1 152 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
DNNHPPPD_00002 2.A.51.1.1 70.3 1.9e-148 3 395 0.9874 0.9776 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.51 The Chromate Ion Transporter (CHR) Family