Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3061
  Reference Plasmid   DSKIN0152-1_bin.4__k141_33387
  Reference Plasmid Size   5465
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070647 NIGFPLHG_00005 2299 5 Skin 0.63 protein_coding missense_variant MODERATE 1487C>A Pro496His
M0070648 NIGFPLHG_00005 2351 3 Skin 0.38 protein_coding synonymous_variant LOW 1435T>C Leu479Leu
M0070649 NIGFPLHG_00005 2604 4 Skin 0.50 protein_coding synonymous_variant LOW 1182C>T Asp394Asp
M0070650 NIGFPLHG_00005 3258 3 Skin 0.38 protein_coding synonymous_variant LOW 528A>G Glu176Glu
M0070651 NIGFPLHG_00005 3363 3 Skin 0.38 protein_coding synonymous_variant LOW 423G>T Ala141Ala
M0070652 NIGFPLHG_00005 3597 3 Skin 0.38 protein_coding synonymous_variant LOW 189C>T Gly63Gly
M0070653 NIGFPLHG_00005 4325 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -540G>A None
M0070654 NIGFPLHG_00008 4972 3 Skin 0.38 protein_coding synonymous_variant LOW 444T>G Gly148Gly
M0070655 NIGFPLHG_00008 5011 3 Skin 0.38 protein_coding synonymous_variant LOW 405T>G Leu135Leu
M0070656 NIGFPLHG_00008 5038 3 Skin 0.38 protein_coding synonymous_variant LOW 378C>T Ala126Ala
M0070657 NIGFPLHG_00008 5133 5 Skin 0.63 protein_coding synonymous_variant LOW 283T>C Leu95Leu
M0070658 NIGFPLHG_00008 5136 3 Skin 0.38 protein_coding missense_variant MODERATE 280G>C Glu94Gln
M0070659 NIGFPLHG_00005 3447 3 Skin 0.38 protein_coding synonymous_variant LOW 339T>G Ser113Ser
M0070660 NIGFPLHG_00005 3465 3 Skin 0.38 protein_coding synonymous_variant LOW 321T>C Pro107Pro
M0070661 NIGFPLHG_00005 3481 3 Skin 0.38 protein_coding missense_variant MODERATE 305T>C Met102Thr
M0070662 NIGFPLHG_00005 3504 3 Skin 0.38 protein_coding missense_variant MODERATE 282C>A Ser94Arg
M0070663 NIGFPLHG_00005 3525 3 Skin 0.38 protein_coding synonymous_variant LOW 261A>C Ala87Ala
M0070664 NIGFPLHG_00005 3660 4 Skin 0.50 protein_coding synonymous_variant LOW 126A>C Arg42Arg
M0070665 NIGFPLHG_00005 3663 4 Skin 0.50 protein_coding synonymous_variant LOW 123G>A Gly41Gly
M0070666 NIGFPLHG_00006 3878 3 Skin 0.38 protein_coding synonymous_variant LOW 288T>A Arg96Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term