Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3062
  Reference Plasmid   DSKIN0152-1_bin.4__k141_39832
  Reference Plasmid Size   23806
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070667 MOPHFBBM_00005 5482 5 Skin 0.45 protein_coding missense_variant MODERATE 683G>A Gly228Asp
M0070668 MOPHFBBM_00005 5496 5 Skin 0.45 protein_coding missense_variant MODERATE 697G>T Asp233Tyr
M0070669 MOPHFBBM_00006 6310 3 Skin 0.27 protein_coding synonymous_variant LOW 438T>C His146His
M0070670 MOPHFBBM_00006 6742 7 Skin 0.64 protein_coding synonymous_variant LOW 870A>C Val290Val
M0070671 MOPHFBBM_00002 6853 7 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -4193A>G None
M0070672 MOPHFBBM_00002 6857 7 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -4197C>G None
M0070673 MOPHFBBM_00007 6958 7 Skin 0.64 protein_coding synonymous_variant LOW 78C>G Pro26Pro
M0070674 MOPHFBBM_00007 7027 8 Skin 0.73 protein_coding synonymous_variant LOW 147C>G Thr49Thr
M0070675 MOPHFBBM_00007 7307 8 Skin 0.73 protein_coding missense_variant MODERATE 427C>A Leu143Ile
M0070676 MOPHFBBM_00007 7583 6 Skin 0.55 protein_coding missense_variant MODERATE 703G>A Val235Ile
M0070677 MOPHFBBM_00007 7627 7 Skin 0.64 protein_coding synonymous_variant LOW 747A>G Gln249Gln
M0070678 MOPHFBBM_00008 7930 3 Skin 0.27 protein_coding synonymous_variant LOW 66T>C Gly22Gly
M0070679 MOPHFBBM_00008 7933 3 Skin 0.27 protein_coding synonymous_variant LOW 69G>T Leu23Leu
M0070680 MOPHFBBM_00008 8245 6 Skin 0.55 protein_coding synonymous_variant LOW 381A>G Ala127Ala
M0070681 MOPHFBBM_00008 8386 7 Skin 0.64 protein_coding synonymous_variant LOW 522T>C Gly174Gly
M0070682 MOPHFBBM_00008 8409 7 Skin 0.64 protein_coding missense_variant MODERATE 545G>T Gly182Val
M0070683 MOPHFBBM_00008 8465 5 Skin 0.45 protein_coding missense_variant MODERATE 601A>G Met201Val
M0070684 MOPHFBBM_00008 8611 4 Skin 0.36 protein_coding synonymous_variant LOW 747T>C Gly249Gly
M0070685 MOPHFBBM_00008 8639 3 Skin 0.27 protein_coding synonymous_variant LOW 775T>C Leu259Leu
M0070686 MOPHFBBM_00008 8758 4 Skin 0.36 protein_coding synonymous_variant LOW 894A>G Ala298Ala
M0070687 MOPHFBBM_00009 9085 6 Skin 0.55 protein_coding missense_variant MODERATE 926A>C Asp309Ala
M0070688 MOPHFBBM_00009 9279 4 Skin 0.36 protein_coding synonymous_variant LOW 732T>C Asp244Asp
M0070689 MOPHFBBM_00009 9302 5 Skin 0.45 protein_coding missense_variant MODERATE 709C>A His237Asn
M0070690 MOPHFBBM_00009 9372 4 Skin 0.36 protein_coding missense_variant MODERATE 639A>G Ile213Met
M0070691 MOPHFBBM_00009 9373 6 Skin 0.55 protein_coding missense_variant MODERATE 638T>A Ile213Lys
M0070692 MOPHFBBM_00009 9384 4 Skin 0.36 protein_coding synonymous_variant LOW 627G>C Arg209Arg
M0070693 MOPHFBBM_00005 5351 4 Skin 0.36 protein_coding synonymous_variant LOW 552C>G Ser184Ser
M0070694 MOPHFBBM_00006 6073 6 Skin 0.55 protein_coding synonymous_variant LOW 201T>C Gly67Gly
M0070695 MOPHFBBM_00006 6076 3 Skin 0.27 protein_coding synonymous_variant LOW 204C>T Ala68Ala
M0070696 MOPHFBBM_00006 6785 6 Skin 0.55 protein_coding missense_variant MODERATE 913A>G Thr305Ala
M0070697 MOPHFBBM_00006 6796 6 Skin 0.55 protein_coding missense_variant MODERATE 924C>G Asp308Glu
M0070698 MOPHFBBM_00008 8518 5 Skin 0.45 protein_coding synonymous_variant LOW 654C>T Asp218Asp
M0070699 MOPHFBBM_00008 8845 6 Skin 0.55 protein_coding synonymous_variant LOW 981G>T Gly327Gly
M0070700 MOPHFBBM_00009 9669 4 Skin 0.36 protein_coding synonymous_variant LOW 342T>C Asp114Asp
M0070701 MOPHFBBM_00009 9696 4 Skin 0.36 protein_coding missense_variant MODERATE 315A>C Glu105Asp
M0070702 MOPHFBBM_00009 9699 4 Skin 0.36 protein_coding synonymous_variant LOW 312C>G Thr104Thr
M0070703 MOPHFBBM_00009 9705 4 Skin 0.36 protein_coding synonymous_variant LOW 306G>C Pro102Pro
M0070704 MOPHFBBM_00009 9708 4 Skin 0.36 protein_coding synonymous_variant LOW 303G>T Ala101Ala
M0070705 MOPHFBBM_00009 9711 4 Skin 0.36 protein_coding synonymous_variant LOW 300C>T Phe100Phe
M0070706 MOPHFBBM_00009 9720 4 Skin 0.36 protein_coding synonymous_variant LOW 291C>G Ser97Ser
M0070707 MOPHFBBM_00009 9723 4 Skin 0.36 protein_coding synonymous_variant LOW 288C>A Gly96Gly
M0070708 MOPHFBBM_00010 10156 3 Skin 0.27 protein_coding missense_variant MODERATE 733C>G Pro245Ala
M0070709 MOPHFBBM_00010 10193 3 Skin 0.27 protein_coding synonymous_variant LOW 696G>T Ala232Ala
M0070710 MOPHFBBM_00010 10502 4 Skin 0.36 protein_coding synonymous_variant LOW 387T>C Asn129Asn
M0070711 MOPHFBBM_00012 13881 3 Skin 0.27 protein_coding synonymous_variant LOW 1572G>T Ala524Ala
M0070712 MOPHFBBM_00014 16275 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -350G>T None
M0070713 MOPHFBBM_00015 16308 3 Skin 0.27 protein_coding missense_variant MODERATE 252T>G Phe84Leu
M0070714 MOPHFBBM_00007 7228 5 Skin 0.45 protein_coding synonymous_variant LOW 348G>T Thr116Thr
M0070715 MOPHFBBM_00007 7429 4 Skin 0.36 protein_coding synonymous_variant LOW 549T>C Asn183Asn
M0070716 MOPHFBBM_00007 7456 5 Skin 0.45 protein_coding synonymous_variant LOW 576G>A Ser192Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term