Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3068
  Reference Plasmid   DT2007044644-1_bin.1__k141_63611
  Reference Plasmid Size   4495
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070758 GDCNJLAD_00001 894 3 Skin 1.00 protein_coding missense_variant MODERATE 784C>G Pro262Ala
M0070759 GDCNJLAD_00001 897 3 Skin 1.00 protein_coding missense_variant MODERATE 787C>G Pro263Ala
M0070760 GDCNJLAD_00001 900 3 Skin 1.00 protein_coding missense_variant MODERATE 790G>C Gly264Arg
M0070761 GDCNJLAD_00001 906 3 Skin 1.00 protein_coding missense_variant MODERATE 796C>G Leu266Val
M0070762 GDCNJLAD_00001 908 3 Skin 1.00 protein_coding synonymous_variant LOW 798G>C Leu266Leu
M0070763 GDCNJLAD_00001 917 3 Skin 1.00 protein_coding synonymous_variant LOW 807T>C Val269Val
M0070764 GDCNJLAD_00001 921 3 Skin 1.00 protein_coding missense_variant MODERATE 811A>G Thr271Ala
M0070765 GDCNJLAD_00001 927 3 Skin 1.00 protein_coding missense_variant MODERATE 817C>G Leu273Val
M0070766 GDCNJLAD_00001 928 3 Skin 1.00 protein_coding missense_variant MODERATE 818T>G Leu273Arg
M0070767 GDCNJLAD_00001 929 3 Skin 1.00 protein_coding synonymous_variant LOW 819T>C Leu273Leu
M0070768 GDCNJLAD_00001 932 3 Skin 1.00 protein_coding missense_variant MODERATE 822G>T Gln274His
M0070769 GDCNJLAD_00001 960 3 Skin 1.00 protein_coding missense_variant MODERATE 850G>C Gly284Arg
M0070770 GDCNJLAD_00001 1050 3 Skin 1.00 protein_coding missense_variant MODERATE 940C>T Leu314Phe
M0070771 GDCNJLAD_00001 1080 3 Skin 1.00 protein_coding missense_variant MODERATE 970A>G Asn324Asp
M0070772 GDCNJLAD_00001 1257 3 Skin 1.00 protein_coding missense_variant MODERATE 1147G>C Gly383Arg
M0070773 GDCNJLAD_00001 1269 3 Skin 1.00 protein_coding missense_variant MODERATE 1159C>G Gln387Glu
M0070774 GDCNJLAD_00001 1278 3 Skin 1.00 protein_coding missense_variant MODERATE 1168G>A Ala390Thr
M0070775 GDCNJLAD_00001 1284 3 Skin 1.00 protein_coding missense_variant MODERATE 1174A>G Lys392Glu
M0070776 GDCNJLAD_00001 1596 3 Skin 1.00 protein_coding missense_variant MODERATE 1486A>C Lys496Gln
M0070777 GDCNJLAD_00002 2076 3 Skin 1.00 protein_coding synonymous_variant LOW 264G>C Arg88Arg
M0070778 GDCNJLAD_00002 2091 3 Skin 1.00 protein_coding synonymous_variant LOW 279G>T Leu93Leu
M0070779 GDCNJLAD_00002 2106 3 Skin 1.00 protein_coding synonymous_variant LOW 294T>G Val98Val
M0070780 GDCNJLAD_00002 2109 3 Skin 1.00 protein_coding synonymous_variant LOW 297C>G Val99Val
M0070781 GDCNJLAD_00002 2121 3 Skin 1.00 protein_coding synonymous_variant LOW 309T>C Asp103Asp
M0070782 GDCNJLAD_00002 2124 3 Skin 1.00 protein_coding synonymous_variant LOW 312C>A Thr104Thr
M0070783 GDCNJLAD_00002 2142 3 Skin 1.00 protein_coding synonymous_variant LOW 330A>G Ser110Ser
M0070784 GDCNJLAD_00002 2172 3 Skin 1.00 protein_coding synonymous_variant LOW 360G>C Gly120Gly
M0070785 GDCNJLAD_00004 3408 3 Skin 1.00 protein_coding synonymous_variant LOW 258G>C Val86Val
M0070786 GDCNJLAD_00004 3411 3 Skin 1.00 protein_coding synonymous_variant LOW 261C>T Asp87Asp
M0070787 GDCNJLAD_00004 3420 3 Skin 1.00 protein_coding synonymous_variant LOW 270G>C Thr90Thr
M0070788 GDCNJLAD_00005 3635 3 Skin 1.00 protein_coding missense_variant MODERATE 845G>T Gly282Val
M0070789 GDCNJLAD_00005 3735 3 Skin 1.00 protein_coding missense_variant MODERATE 745G>A Ala249Thr
M0070790 GDCNJLAD_00005 3793 3 Skin 1.00 protein_coding synonymous_variant LOW 687C>T Asp229Asp
M0070791 GDCNJLAD_00005 3825 3 Skin 1.00 protein_coding missense_variant MODERATE 655G>T Ala219Ser
M0070792 GDCNJLAD_00005 3842 3 Skin 1.00 protein_coding missense_variant MODERATE 638G>C Arg213Pro
M0070793 GDCNJLAD_00005 3865 3 Skin 1.00 protein_coding synonymous_variant LOW 615T>C Asp205Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term