Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3070
  Reference Plasmid   DT2007044659-1_bin.2__k141_38370
  Reference Plasmid Size   3580
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0070797 IBKMEJNA_00002 1212 7 Skin 0.41 protein_coding upstream_gene_variant MODIFIER -150A>T None
M0070798 IBKMEJNA_00002 1544 5 Skin 0.29 protein_coding synonymous_variant LOW 183T>C Pro61Pro
M0070799 IBKMEJNA_00002 1559 13 Skin 0.76 protein_coding synonymous_variant LOW 198C>T Ser66Ser
M0070800 IBKMEJNA_00002 1601 12 Skin 0.71 protein_coding synonymous_variant LOW 240G>A Gln80Gln
M0070801 IBKMEJNA_00001 210 3 Skin 0.18 protein_coding synonymous_variant LOW 15G>A Thr5Thr
M0070802 IBKMEJNA_00001 420 5 Skin 0.29 protein_coding synonymous_variant LOW 225A>G Lys75Lys
M0070803 IBKMEJNA_00001 432 5 Skin 0.29 protein_coding synonymous_variant LOW 237T>G Ser79Ser
M0070804 IBKMEJNA_00001 765 11 Skin 0.65 protein_coding synonymous_variant LOW 570T>C Gly190Gly
M0070805 IBKMEJNA_00002 948 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -414T>G None
M0070806 IBKMEJNA_00002 1031 9 Skin 0.53 protein_coding upstream_gene_variant MODIFIER -331C>G None
M0070807 IBKMEJNA_00002 1074 7 Skin 0.41 protein_coding upstream_gene_variant MODIFIER -288T>C None
M0070808 IBKMEJNA_00002 1082 7 Skin 0.41 protein_coding upstream_gene_variant MODIFIER -280A>G None
M0070809 IBKMEJNA_00002 1127 7 Skin 0.41 protein_coding upstream_gene_variant MODIFIER -235G>C None
M0070810 IBKMEJNA_00002 1312 6 Skin 0.35 protein_coding upstream_gene_variant MODIFIER -50C>A None
M0070811 IBKMEJNA_00002 1683 11 Skin 0.65 protein_coding missense_variant MODERATE 322A>G Ile108Val
M0070812 IBKMEJNA_00002 1817 5 Skin 0.29 protein_coding synonymous_variant LOW 456T>C His152His
M0070813 IBKMEJNA_00001 2001 5 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *1080C>A None
M0070814 IBKMEJNA_00001 2012 6 Skin 0.35 protein_coding downstream_gene_variant MODIFIER *1091A>T None
M0070815 IBKMEJNA_00001 2014 5 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *1093A>T None
M0070816 IBKMEJNA_00001 2019 7 Skin 0.41 protein_coding downstream_gene_variant MODIFIER *1098T>G None
M0070817 IBKMEJNA_00001 2022 5 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *1101A>G None
M0070818 IBKMEJNA_00001 2040 5 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *1119A>G None
M0070819 IBKMEJNA_00003 2212 3 Skin 0.18 protein_coding missense_variant MODERATE 824G>A Gly275Asp
M0070820 IBKMEJNA_00003 2400 5 Skin 0.29 protein_coding synonymous_variant LOW 636G>A Arg212Arg
M0070821 IBKMEJNA_00001 354 4 Skin 0.24 protein_coding synonymous_variant LOW 159C>T Cys53Cys
M0070822 IBKMEJNA_00001 891 5 Skin 0.29 protein_coding synonymous_variant LOW 696G>T Leu232Leu
M0070823 IBKMEJNA_00002 1105 6 Skin 0.35 protein_coding upstream_gene_variant MODIFIER -257G>T None
M0070824 IBKMEJNA_00002 1136 6 Skin 0.35 protein_coding upstream_gene_variant MODIFIER -226T>C None
M0070825 IBKMEJNA_00002 1284 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -78C>A None
M0070826 IBKMEJNA_00003 2838 4 Skin 0.24 protein_coding synonymous_variant LOW 198T>C Ile66Ile
M0070827 IBKMEJNA_00003 2855 4 Skin 0.24 protein_coding synonymous_variant LOW 181T>C Leu61Leu
M0070828 IBKMEJNA_00003 3118 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -83G>A None
M0070829 IBKMEJNA_00002 1283 8 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -79C>T None
M0070830 IBKMEJNA_00001 333 4 Skin 0.24 protein_coding synonymous_variant LOW 138G>A Glu46Glu
M0070831 IBKMEJNA_00001 405 4 Skin 0.24 protein_coding synonymous_variant LOW 210G>A Thr70Thr
M0070832 IBKMEJNA_00001 408 4 Skin 0.24 protein_coding synonymous_variant LOW 213A>G Lys71Lys
M0070833 IBKMEJNA_00001 429 4 Skin 0.24 protein_coding synonymous_variant LOW 234T>G Thr78Thr
M0070834 IBKMEJNA_00001 678 5 Skin 0.29 protein_coding synonymous_variant LOW 483C>T Gly161Gly
M0070835 IBKMEJNA_00001 849 5 Skin 0.29 protein_coding synonymous_variant LOW 654G>A Lys218Lys
M0070836 IBKMEJNA_00001 855 5 Skin 0.29 protein_coding synonymous_variant LOW 660C>T Ile220Ile
M0070837 IBKMEJNA_00001 864 5 Skin 0.29 protein_coding synonymous_variant LOW 669A>C Thr223Thr
M0070838 IBKMEJNA_00002 1244 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -118A>G None
M0070839 IBKMEJNA_00002 1246 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -116T>C None
M0070840 IBKMEJNA_00002 1257 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -105A>T None
M0070841 IBKMEJNA_00002 1266 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -96G>A None
M0070842 IBKMEJNA_00002 1287 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -75T>C None
M0070843 IBKMEJNA_00002 1296 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -66C>T None
M0070844 IBKMEJNA_00002 1314 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -48T>A None
M0070845 IBKMEJNA_00002 1315 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -47A>G None
M0070846 IBKMEJNA_00002 1391 5 Skin 0.29 protein_coding synonymous_variant LOW 30A>T Thr10Thr
M0070847 IBKMEJNA_00002 1463 5 Skin 0.29 protein_coding synonymous_variant LOW 102C>T His34His
M0070848 IBKMEJNA_00002 1499 5 Skin 0.29 protein_coding synonymous_variant LOW 138T>A Ser46Ser
M0070849 IBKMEJNA_00002 1514 5 Skin 0.29 protein_coding synonymous_variant LOW 153T>A Ala51Ala
M0070850 IBKMEJNA_00002 1518 5 Skin 0.29 protein_coding missense_variant MODERATE 157G>A Glu53Lys
M0070851 IBKMEJNA_00002 1555 5 Skin 0.29 protein_coding missense_variant MODERATE 194A>C Asn65Thr
M0070852 IBKMEJNA_00002 1635 4 Skin 0.24 protein_coding missense_variant MODERATE 274G>A Val92Ile
M0070853 IBKMEJNA_00002 1652 4 Skin 0.24 protein_coding synonymous_variant LOW 291T>C Ile97Ile
M0070854 IBKMEJNA_00002 1745 4 Skin 0.24 protein_coding missense_variant MODERATE 384T>A Asn128Lys
M0070855 IBKMEJNA_00002 1777 5 Skin 0.29 protein_coding missense_variant MODERATE 416A>G Asn139Ser
M0070856 IBKMEJNA_00001 831 3 Skin 0.18 protein_coding synonymous_variant LOW 636G>T Gly212Gly
M0070857 IBKMEJNA_00002 929 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -433T>C None
M0070858 IBKMEJNA_00002 1811 3 Skin 0.18 protein_coding synonymous_variant LOW 450C>G Val150Val
M0070859 IBKMEJNA_00002 1853 4 Skin 0.24 protein_coding missense_variant MODERATE 492T>A His164Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term