Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C227
  Reference Plasmid   HG796770.1
  Reference Plasmid Size   8882
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0149107 OFBDFIBP_00007 3945 9 Gut 0.47 protein_coding missense_variant MODERATE 223C>T Pro75Ser
M0149108 OFBDFIBP_00004 1945 4 Gut 0.21 protein_coding missense_variant MODERATE 152T>C Leu51Ser
M0149109 OFBDFIBP_00004 1948 4 Gut 0.21 protein_coding stop_gained HIGH 155G>A Trp52*
M0149110 OFBDFIBP_00005 2137 4 Gut 0.21 protein_coding synonymous_variant LOW 873T>A Val291Val
M0149111 OFBDFIBP_00005 2163 6 Gut 0.32 protein_coding missense_variant MODERATE 847C>A Gln283Lys
M0149112 OFBDFIBP_00005 2170 4 Gut 0.21 protein_coding synonymous_variant LOW 840G>T Ala280Ala
M0149113 OFBDFIBP_00005 2302 4 Gut 0.21 protein_coding synonymous_variant LOW 708A>G Glu236Glu
M0149114 OFBDFIBP_00005 2341 4 Gut 0.21 protein_coding synonymous_variant LOW 669A>G Leu223Leu
M0149115 OFBDFIBP_00005 2560 5 Gut 0.26 protein_coding missense_variant MODERATE 450T>G Asp150Glu
M0149116 OFBDFIBP_00005 2684 4 Gut 0.21 protein_coding missense_variant MODERATE 326T>A Leu109Gln
M0149117 OFBDFIBP_00005 2086 3 Gut 0.16 protein_coding synonymous_variant LOW 924C>T Tyr308Tyr
M0149118 OFBDFIBP_00005 2135 3 Gut 0.16 protein_coding missense_variant MODERATE 875C>T Ser292Leu
M0149119 OFBDFIBP_00005 2293 3 Gut 0.16 protein_coding synonymous_variant LOW 717T>A Thr239Thr
M0149120 OFBDFIBP_00005 2356 3 Gut 0.16 protein_coding synonymous_variant LOW 654A>G Glu218Glu
M0149121 OFBDFIBP_00005 2475 3 Gut 0.16 protein_coding missense_variant MODERATE 535G>A Val179Ile
M0149122 OFBDFIBP_00005 2776 3 Gut 0.16 protein_coding synonymous_variant LOW 234C>A Gly78Gly
M0149123 OFBDFIBP_00005 2812 3 Gut 0.16 protein_coding synonymous_variant LOW 198C>T Asp66Asp
M0149124 OFBDFIBP_00005 2845 3 Gut 0.16 protein_coding synonymous_variant LOW 165G>A Arg55Arg
M0149125 OFBDFIBP_00006 3302 3 Gut 0.16 protein_coding synonymous_variant LOW 123C>T Asn41Asn
M0149126 OFBDFIBP_00006 3384 3 Gut 0.16 protein_coding missense_variant MODERATE 41A>G Gln14Arg
M0149127 OFBDFIBP_00003 3626 4 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -2322T>C None
M0149128 OFBDFIBP_00001 496 3 Gut 0.16 protein_coding synonymous_variant LOW 105C>T Phe35Phe
M0149129 OFBDFIBP_00001 544 4 Gut 0.21 protein_coding synonymous_variant LOW 153G>A Glu51Glu
M0149130 OFBDFIBP_00001 562 3 Gut 0.16 protein_coding synonymous_variant LOW 171G>A Glu57Glu
M0149131 OFBDFIBP_00001 598 3 Gut 0.16 protein_coding synonymous_variant LOW 207T>C Asp69Asp
M0149132 OFBDFIBP_00002 738 3 Gut 0.16 protein_coding synonymous_variant LOW 102A>G Leu34Leu
M0149133 OFBDFIBP_00002 819 3 Gut 0.16 protein_coding synonymous_variant LOW 183C>A Val61Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term