Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C234
  Reference Plasmid   HG796820.1
  Reference Plasmid Size   2261
  Reference Plasmid GC Content   0.45
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0149357 ELIGGLCO_00001 52 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -123A>G None
M0149358 ELIGGLCO_00001 111 6 Gut 0.86 protein_coding upstream_gene_variant MODIFIER -64A>C None
M0149359 ELIGGLCO_00001 154 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -21C>T None
M0149360 ELIGGLCO_00001 166 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -9G>A None
M0149361 ELIGGLCO_00001 169 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -6A>G None
M0149362 ELIGGLCO_00001 174 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -1C>A None
M0149363 ELIGGLCO_00001 220 7 Gut 1.00 protein_coding missense_variant MODERATE 46T>G Ser16Ala
M0149364 ELIGGLCO_00001 249 7 Gut 1.00 protein_coding synonymous_variant LOW 75C>T Asn25Asn
M0149365 ELIGGLCO_00001 291 7 Gut 1.00 protein_coding synonymous_variant LOW 117T>C Gly39Gly
M0149366 ELIGGLCO_00001 300 6 Gut 0.86 protein_coding synonymous_variant LOW 126A>C Thr42Thr
M0149367 ELIGGLCO_00001 318 7 Gut 1.00 protein_coding synonymous_variant LOW 144C>T His48His
M0149368 ELIGGLCO_00001 336 7 Gut 1.00 protein_coding synonymous_variant LOW 162C>T Thr54Thr
M0149369 ELIGGLCO_00001 351 7 Gut 1.00 protein_coding synonymous_variant LOW 177A>G Glu59Glu
M0149370 ELIGGLCO_00001 363 7 Gut 1.00 protein_coding synonymous_variant LOW 189T>C Leu63Leu
M0149371 ELIGGLCO_00001 441 7 Gut 1.00 protein_coding synonymous_variant LOW 267T>C Thr89Thr
M0149372 ELIGGLCO_00001 465 7 Gut 1.00 protein_coding synonymous_variant LOW 291C>T Val97Val
M0149373 ELIGGLCO_00001 513 7 Gut 1.00 protein_coding synonymous_variant LOW 339T>G Arg113Arg
M0149374 ELIGGLCO_00001 537 7 Gut 1.00 protein_coding synonymous_variant LOW 363T>G Arg121Arg
M0149375 ELIGGLCO_00001 561 7 Gut 1.00 protein_coding synonymous_variant LOW 387T>C Tyr129Tyr
M0149376 ELIGGLCO_00001 570 7 Gut 1.00 protein_coding synonymous_variant LOW 396C>T Ile132Ile
M0149377 ELIGGLCO_00001 657 7 Gut 1.00 protein_coding synonymous_variant LOW 483T>G Ala161Ala
M0149378 ELIGGLCO_00001 690 7 Gut 1.00 protein_coding synonymous_variant LOW 516T>G Val172Val
M0149379 ELIGGLCO_00001 726 7 Gut 1.00 protein_coding synonymous_variant LOW 552T>C Gly184Gly
M0149380 ELIGGLCO_00001 741 7 Gut 1.00 protein_coding synonymous_variant LOW 567C>T Ala189Ala
M0149381 ELIGGLCO_00001 763 7 Gut 1.00 protein_coding missense_variant MODERATE 589G>T Ala197Ser
M0149382 ELIGGLCO_00001 798 7 Gut 1.00 protein_coding synonymous_variant LOW 624T>C Tyr208Tyr
M0149383 ELIGGLCO_00001 855 7 Gut 1.00 protein_coding synonymous_variant LOW 681G>A Lys227Lys
M0149384 ELIGGLCO_00001 918 7 Gut 1.00 protein_coding synonymous_variant LOW 744T>C Ser248Ser
M0149385 ELIGGLCO_00001 933 7 Gut 1.00 protein_coding synonymous_variant LOW 759A>G Lys253Lys
M0149386 ELIGGLCO_00001 936 7 Gut 1.00 protein_coding synonymous_variant LOW 762G>T Pro254Pro
M0149387 ELIGGLCO_00001 957 7 Gut 1.00 protein_coding synonymous_variant LOW 783T>C Tyr261Tyr
M0149388 ELIGGLCO_00001 962 7 Gut 1.00 protein_coding missense_variant MODERATE 788G>A Arg263Lys
M0149389 ELIGGLCO_00001 986 7 Gut 1.00 protein_coding missense_variant MODERATE 812C>G Ala271Gly
M0149390 ELIGGLCO_00002 1084 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -93G>A None
M0149391 ELIGGLCO_00002 1096 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -81T>G None
M0149392 ELIGGLCO_00002 1106 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -71T>A None
M0149393 ELIGGLCO_00002 1107 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -70T>A None
M0149394 ELIGGLCO_00002 1108 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -69T>A None
M0149395 ELIGGLCO_00002 1109 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -68T>A None
M0149396 ELIGGLCO_00002 1146 7 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -31T>C None
M0149397 ELIGGLCO_00002 1161 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -16C>T None
M0149398 ELIGGLCO_00002 1182 6 Gut 0.86 protein_coding synonymous_variant LOW 6T>G Leu2Leu
M0149399 ELIGGLCO_00002 1233 7 Gut 1.00 protein_coding synonymous_variant LOW 57C>T Asp19Asp
M0149400 ELIGGLCO_00002 1314 7 Gut 1.00 protein_coding synonymous_variant LOW 138G>A Glu46Glu
M0149401 ELIGGLCO_00002 1317 7 Gut 1.00 protein_coding synonymous_variant LOW 141G>A Lys47Lys
M0149402 ELIGGLCO_00002 1323 7 Gut 1.00 protein_coding synonymous_variant LOW 147A>T Gly49Gly
M0149403 ELIGGLCO_00002 1334 7 Gut 1.00 protein_coding missense_variant MODERATE 158T>C Leu53Ser
M0149404 ELIGGLCO_00002 1335 7 Gut 1.00 protein_coding missense_variant MODERATE 159G>C Leu53Phe
M0149405 ELIGGLCO_00002 1338 7 Gut 1.00 protein_coding synonymous_variant LOW 162T>C Gly54Gly
M0149406 ELIGGLCO_00002 1344 7 Gut 1.00 protein_coding synonymous_variant LOW 168C>T Ser56Ser
M0149407 ELIGGLCO_00002 1353 6 Gut 0.86 protein_coding synonymous_variant LOW 177T>C Gly59Gly
M0149408 ELIGGLCO_00002 1364 7 Gut 1.00 protein_coding missense_variant MODERATE 188A>G Gln63Arg
M0149409 ELIGGLCO_00002 1407 7 Gut 1.00 protein_coding synonymous_variant LOW 231C>A Ser77Ser
M0149410 ELIGGLCO_00002 1408 7 Gut 1.00 protein_coding synonymous_variant LOW 232C>T Leu78Leu
M0149411 ELIGGLCO_00002 1423 7 Gut 1.00 protein_coding synonymous_variant LOW 247A>C Arg83Arg
M0149412 ELIGGLCO_00002 1443 7 Gut 1.00 protein_coding synonymous_variant LOW 267A>T Ile89Ile
M0149413 ELIGGLCO_00002 1470 7 Gut 1.00 protein_coding synonymous_variant LOW 294G>A Gln98Gln
M0149414 ELIGGLCO_00002 1473 7 Gut 1.00 protein_coding synonymous_variant LOW 297T>C Leu99Leu
M0149415 ELIGGLCO_00002 1506 7 Gut 1.00 protein_coding synonymous_variant LOW 330A>G Leu110Leu
M0149416 ELIGGLCO_00002 1561 7 Gut 1.00 protein_coding synonymous_variant LOW 385T>C Leu129Leu
M0149417 ELIGGLCO_00001 1594 7 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *511A>C None
M0149418 ELIGGLCO_00001 1654 6 Gut 0.86 protein_coding downstream_gene_variant MODIFIER *571G>C None
M0149419 ELIGGLCO_00001 1692 5 Gut 0.71 protein_coding downstream_gene_variant MODIFIER *609A>G None
M0149420 ELIGGLCO_00001 1788 7 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *705C>T None
M0149421 ELIGGLCO_00001 1820 7 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *737G>T None
M0149422 ELIGGLCO_00001 1836 7 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *753G>A None
M0149423 ELIGGLCO_00001 1863 7 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *780G>A None
M0149424 ELIGGLCO_00001 1866 7 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *783A>G None
M0149425 ELIGGLCO_00001 1876 7 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *793C>T None
M0149426 ELIGGLCO_00001 1889 7 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *806T>G None
M0149427 ELIGGLCO_00001 864 6 Gut 0.86 protein_coding synonymous_variant LOW 690T>C Ile230Ile
M0149428 ELIGGLCO_00002 1345 6 Gut 0.86 protein_coding missense_variant MODERATE 169T>C Ser57Pro
M0149429 ELIGGLCO_00001 1983 6 Gut 0.86 protein_coding downstream_gene_variant MODIFIER *900C>T None
M0149430 ELIGGLCO_00001 2049 6 Gut 0.86 protein_coding downstream_gene_variant MODIFIER *966C>T None
M0149431 ELIGGLCO_00001 2064 6 Gut 0.86 protein_coding downstream_gene_variant MODIFIER *981C>T None
M0149432 ELIGGLCO_00002 1260 4 Gut 0.57 protein_coding synonymous_variant LOW 84C>T Pro28Pro
M0149433 ELIGGLCO_00001 426 3 Gut 0.43 protein_coding synonymous_variant LOW 252G>A Leu84Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term