Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C241
  Reference Plasmid   LC817946.1
  Reference Plasmid Size   5602
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0149469 KBHLNKJE_00001 59 8 Gut 0.10 protein_coding downstream_gene_variant MODIFIER *861A>G None
M0149470 KBHLNKJE_00001 73 9 Gut 0.11 protein_coding downstream_gene_variant MODIFIER *847T>C None
M0149471 KBHLNKJE_00001 116 10 Gut 0.13 protein_coding downstream_gene_variant MODIFIER *804C>T None
M0149472 KBHLNKJE_00001 146 12 Gut 0.15 protein_coding downstream_gene_variant MODIFIER *774A>G None
M0149473 KBHLNKJE_00001 197 9 Gut 0.11 protein_coding downstream_gene_variant MODIFIER *723A>G None
M0149474 KBHLNKJE_00001 319 10 Gut 0.13 protein_coding downstream_gene_variant MODIFIER *601A>G None
M0149475 KBHLNKJE_00001 373 9 Gut 0.11 protein_coding downstream_gene_variant MODIFIER *547G>T None
M0149476 KBHLNKJE_00001 404 9 Gut 0.11 protein_coding downstream_gene_variant MODIFIER *516A>G None
M0149477 KBHLNKJE_00005 5283 8 Gut 0.10 protein_coding synonymous_variant LOW 210G>A Val70Val
M0149478 KBHLNKJE_00005 5362 7 Gut 0.09 protein_coding missense_variant MODERATE 131A>G Asp44Gly
M0149479 KBHLNKJE_00001 498 10 Gut 0.13 protein_coding downstream_gene_variant MODIFIER *422T>C None
M0149480 KBHLNKJE_00003 3183 4 Gut 0.05 protein_coding synonymous_variant LOW 78G>A Glu26Glu
M0149481 KBHLNKJE_00004 3337 4 Gut 0.05 protein_coding synonymous_variant LOW 552G>A Lys184Lys
M0149482 KBHLNKJE_00004 3430 3 Gut 0.04 protein_coding synonymous_variant LOW 459A>G Glu153Glu
M0149483 KBHLNKJE_00004 3472 17 Gut 0.22 protein_coding missense_variant MODERATE 417T>A Phe139Leu
M0149484 KBHLNKJE_00004 3473 17 Gut 0.22 protein_coding missense_variant MODERATE 416T>G Phe139Cys
M0149485 KBHLNKJE_00004 3474 17 Gut 0.22 protein_coding missense_variant MODERATE 415T>A Phe139Ile
M0149486 KBHLNKJE_00004 3484 17 Gut 0.22 protein_coding synonymous_variant LOW 405T>C Tyr135Tyr
M0149487 KBHLNKJE_00001 4058 7 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -2584A>C None
M0149488 KBHLNKJE_00001 509 9 Gut 0.11 protein_coding downstream_gene_variant MODIFIER *411G>A None
M0149489 KBHLNKJE_00001 546 9 Gut 0.11 protein_coding downstream_gene_variant MODIFIER *374A>T None
M0149490 KBHLNKJE_00004 3315 12 Gut 0.15 protein_coding missense_variant MODERATE 574A>G Asn192Asp
M0149491 KBHLNKJE_00004 3493 7 Gut 0.09 protein_coding synonymous_variant LOW 396C>T Tyr132Tyr
M0149492 KBHLNKJE_00004 3544 17 Gut 0.22 protein_coding synonymous_variant LOW 345T>C Ile115Ile
M0149493 KBHLNKJE_00004 3565 4 Gut 0.05 protein_coding synonymous_variant LOW 324A>G Thr108Thr
M0149494 KBHLNKJE_00004 3613 6 Gut 0.08 protein_coding missense_variant MODERATE 276G>T Leu92Phe
M0149495 KBHLNKJE_00004 3730 4 Gut 0.05 protein_coding synonymous_variant LOW 159G>A Leu53Leu
M0149496 KBHLNKJE_00004 3757 4 Gut 0.05 protein_coding synonymous_variant LOW 132G>A Glu44Glu
M0149497 KBHLNKJE_00004 3766 7 Gut 0.09 protein_coding synonymous_variant LOW 123A>T Thr41Thr
M0149498 KBHLNKJE_00004 3780 15 Gut 0.19 protein_coding missense_variant MODERATE 109A>G Lys37Glu
M0149499 KBHLNKJE_00004 3793 7 Gut 0.09 protein_coding synonymous_variant LOW 96G>A Ala32Ala
M0149500 KBHLNKJE_00004 3853 7 Gut 0.09 protein_coding synonymous_variant LOW 36G>A Glu12Glu
M0149501 KBHLNKJE_00003 3036 3 Gut 0.04 protein_coding synonymous_variant LOW 225T>C Asn75Asn
M0149502 KBHLNKJE_00004 3568 3 Gut 0.04 protein_coding synonymous_variant LOW 321G>A Glu107Glu
M0149503 KBHLNKJE_00001 4055 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -2581C>T None
M0149504 KBHLNKJE_00004 3577 5 Gut 0.06 protein_coding synonymous_variant LOW 312G>A Glu104Glu
M0149505 KBHLNKJE_00004 3607 5 Gut 0.06 protein_coding synonymous_variant LOW 282T>C Tyr94Tyr
M0149506 KBHLNKJE_00004 3610 5 Gut 0.06 protein_coding synonymous_variant LOW 279T>G Gly93Gly
M0149507 KBHLNKJE_00002 2662 3 Gut 0.04 protein_coding missense_variant MODERATE 318A>C Lys106Asn
M0149508 KBHLNKJE_00002 2664 3 Gut 0.04 protein_coding missense_variant MODERATE 316A>G Lys106Glu
M0149509 KBHLNKJE_00001 581 7 Gut 0.09 protein_coding downstream_gene_variant MODIFIER *339T>C None
M0149510 KBHLNKJE_00001 584 7 Gut 0.09 protein_coding downstream_gene_variant MODIFIER *336G>A None
M0149511 KBHLNKJE_00001 588 11 Gut 0.14 protein_coding downstream_gene_variant MODIFIER *332G>A None
M0149512 KBHLNKJE_00001 4217 5 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2743T>C None
M0149513 KBHLNKJE_00001 4219 5 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2745C>T None
M0149514 KBHLNKJE_00001 4271 4 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -2797T>C None
M0149515 KBHLNKJE_00001 4295 4 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -2821C>T None
M0149516 KBHLNKJE_00001 4319 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -2845G>A None
M0149517 KBHLNKJE_00001 4332 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -2858C>A None
M0149518 KBHLNKJE_00001 4375 5 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2901A>T None
M0149519 KBHLNKJE_00001 4409 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -2935G>A None
M0149520 KBHLNKJE_00001 4470 6 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -2996T>C None
M0149521 KBHLNKJE_00004 3298 5 Gut 0.06 protein_coding synonymous_variant LOW 591C>A Leu197Leu
M0149522 KBHLNKJE_00004 3347 4 Gut 0.05 protein_coding missense_variant MODERATE 542C>A Ala181Glu
M0149523 KBHLNKJE_00004 3679 6 Gut 0.08 protein_coding synonymous_variant LOW 210G>A Gln70Gln
M0149524 KBHLNKJE_00004 3709 5 Gut 0.06 protein_coding synonymous_variant LOW 180T>C Asn60Asn
M0149525 KBHLNKJE_00004 3727 5 Gut 0.06 protein_coding synonymous_variant LOW 162G>T Val54Val
M0149526 KBHLNKJE_00002 2126 4 Gut 0.05 protein_coding missense_variant MODERATE 854A>C Asp285Ala
M0149527 KBHLNKJE_00002 2128 3 Gut 0.04 protein_coding synonymous_variant LOW 852G>A Thr284Thr
M0149528 KBHLNKJE_00002 2274 6 Gut 0.08 protein_coding missense_variant MODERATE 706A>G Lys236Glu
M0149529 KBHLNKJE_00002 2302 3 Gut 0.04 protein_coding synonymous_variant LOW 678A>G Lys226Lys
M0149530 KBHLNKJE_00002 2353 4 Gut 0.05 protein_coding synonymous_variant LOW 627T>C Ile209Ile
M0149531 KBHLNKJE_00002 2360 3 Gut 0.04 protein_coding missense_variant MODERATE 620G>C Ser207Thr
M0149532 KBHLNKJE_00002 2712 6 Gut 0.08 protein_coding missense_variant MODERATE 268T>C Ser90Pro
M0149533 KBHLNKJE_00003 3231 4 Gut 0.05 protein_coding synonymous_variant LOW 30T>C Val10Val
M0149534 KBHLNKJE_00001 3950 8 Gut 0.10 protein_coding upstream_gene_variant MODIFIER -2476G>T None
M0149535 KBHLNKJE_00004 3867 6 Gut 0.08 protein_coding missense_variant MODERATE 22C>A Gln8Lys
M0149536 KBHLNKJE_00004 3874 6 Gut 0.08 protein_coding synonymous_variant LOW 15G>A Glu5Glu
M0149537 KBHLNKJE_00001 3906 6 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -2432A>T None
M0149538 KBHLNKJE_00001 3927 6 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -2453A>T None
M0149539 KBHLNKJE_00001 3930 6 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -2456T>A None
M0149540 KBHLNKJE_00001 3948 6 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -2474G>A None
M0149541 KBHLNKJE_00001 3951 6 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -2477T>G None
M0149542 KBHLNKJE_00001 4052 5 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2578T>A None
M0149543 KBHLNKJE_00002 2529 4 Gut 0.05 protein_coding missense_variant MODERATE 451T>C Ser151Pro
M0149544 KBHLNKJE_00002 2593 3 Gut 0.04 protein_coding synonymous_variant LOW 387C>T Ser129Ser
M0149545 KBHLNKJE_00005 5063 4 Gut 0.05 protein_coding synonymous_variant LOW 430T>C Leu144Leu
M0149546 KBHLNKJE_00001 4741 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -3267T>C None
M0149547 KBHLNKJE_00005 5076 3 Gut 0.04 protein_coding synonymous_variant LOW 417T>C Asp139Asp
M0149548 KBHLNKJE_00005 5079 3 Gut 0.04 protein_coding synonymous_variant LOW 414A>G Glu138Glu
M0149549 KBHLNKJE_00005 5082 3 Gut 0.04 protein_coding synonymous_variant LOW 411G>A Arg137Arg
M0149550 KBHLNKJE_00005 5085 3 Gut 0.04 protein_coding synonymous_variant LOW 408A>C Thr136Thr
M0149551 KBHLNKJE_00001 1246 3 Gut 0.04 protein_coding missense_variant MODERATE 229A>G Ile77Val
M0149552 KBHLNKJE_00001 1507 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -33C>T None
M0149553 KBHLNKJE_00001 1569 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -95T>C None
M0149554 KBHLNKJE_00001 1710 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -236C>T None
M0149555 KBHLNKJE_00002 2815 4 Gut 0.05 protein_coding synonymous_variant LOW 165C>A Thr55Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term