Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C266
  Reference Plasmid   LR962812.1
  Reference Plasmid Size   60951
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0150533 ILOADOEM_00020 19880 3 Gut 0.60 protein_coding synonymous_variant LOW 492T>C Ala164Ala
M0150534 ILOADOEM_00020 20009 4 Gut 0.80 protein_coding synonymous_variant LOW 621C>A Gly207Gly
M0150535 ILOADOEM_00020 20214 3 Gut 0.60 protein_coding synonymous_variant LOW 826T>C Leu276Leu
M0150536 ILOADOEM_00020 20573 3 Gut 0.60 protein_coding synonymous_variant LOW 1185T>A Thr395Thr
M0150537 ILOADOEM_00020 21098 3 Gut 0.60 protein_coding synonymous_variant LOW 1710T>C Asp570Asp
M0150538 ILOADOEM_00021 21844 3 Gut 0.60 protein_coding synonymous_variant LOW 54T>A Val18Val
M0150539 ILOADOEM_00021 21910 3 Gut 0.60 protein_coding synonymous_variant LOW 120G>A Ala40Ala
M0150540 ILOADOEM_00021 21982 3 Gut 0.60 protein_coding synonymous_variant LOW 192T>C Leu64Leu
M0150541 ILOADOEM_00021 22090 3 Gut 0.60 protein_coding synonymous_variant LOW 300G>A Arg100Arg
M0150542 ILOADOEM_00021 22106 3 Gut 0.60 protein_coding missense_variant MODERATE 316C>G Gln106Glu
M0150543 ILOADOEM_00021 22111 3 Gut 0.60 protein_coding synonymous_variant LOW 321A>G Thr107Thr
M0150544 ILOADOEM_00021 22293 3 Gut 0.60 protein_coding missense_variant MODERATE 503G>A Ser168Asn
M0150545 ILOADOEM_00021 22394 3 Gut 0.60 protein_coding missense_variant MODERATE 604G>T Val202Leu
M0150546 ILOADOEM_00014 17090 3 Gut 0.60 protein_coding synonymous_variant LOW 762T>C Leu254Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
ILOADOEM_00011 VFG002164 AS 96.6 0 1 1305 1.0 1 Adherence aggregation substance PrgB/Asc10 experiment
ILOADOEM_00011 VFG002164 AS 96.6 0 1 1305 1.0 1 Adherence aggregation substance PrgB/Asc10 prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
ILOADOEM_00048 BAG12399.1|GH24 100 0 1 595 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
ILOADOEM_00029 3.A.7.19.1 99.3 0 1 609 1.0000 1.0856 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
ILOADOEM_00030 3.A.7.19.1 99.2 0 1 719 1.0000 1.2816 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
ILOADOEM_00033 3.A.7.19.1 97.3 1.20000000000606e-313 1 561 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
ILOADOEM_00035 3.A.7.19.1 93 1.2e-244 3 447 0.9955 0.7932 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family